Integrated use of minimal residual disease classification and IKZF1 alteration status accurately predicts 79% of relapses in pediatric acute lymphoblastic leukemia.
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New and emerging prognostic and predictive genetic biomarkers in B-cell precursor acute lymphoblastic leukemiaMinimal residual disease diagnostics in acute lymphoblastic leukemia: need for sensitive, fast, and standardized technologiesGenomic profiling of B-progenitor acute lymphoblastic leukemiaRedefining ALL classification: toward detecting high-risk ALL and implementing precision medicinePrognostic value of genetic alterations in children with first bone marrow relapse of childhood B-cell precursor acute lymphoblastic leukemia.Use of single nucleotide polymorphism array technology to improve the identification of chromosomal lesions in leukemiaTumor suppressors BTG1 and IKZF1 cooperate during mouse leukemia development and increase relapse risk in B-cell precursor acute lymphoblastic leukemia patients.Development-associated immunophenotypes reveal the heterogeneous and individualized early responses of adult B-acute lymphoblastic leukemia.The origin and nature of tightly clustered BTG1 deletions in precursor B-cell acute lymphoblastic leukemia support a model of multiclonal evolution.A set of miRNAs that involve in the pathways of drug resistance and leukemic stem-cell differentiation is associated with the risk of relapse and glucocorticoid response in childhood ALLIKAROS deletions dictate a unique gene expression signature in patients with adult B-cell acute lymphoblastic leukemiaBET inhibition as a single or combined therapeutic approach in primary paediatric B-precursor acute lymphoblastic leukaemia.Ikaros deficiency in host hematopoietic cells separates GVL from GVHD after experimental allogeneic hematopoietic cell transplantationLoss of Ikaros DNA-binding function confers integrin-dependent survival on pre-B cells and progression to acute lymphoblastic leukemiaIkaros6 is associated with BCR-ABL1 and myeloid-associated antigens but indicates poor prognosis independently in Chinese adult B-cell acute lymphoblastic leukemia.Minimal Residual Disease in AML: Why Has It Lagged Behind Pediatric ALL?CD200/BTLA deletions in pediatric precursor B-cell acute lymphoblastic leukemia treated according to the EORTC-CLG 58951 protocol.Alternative Splice Variants Modulates Dominant-Negative Function of Helios in T-Cell Leukemia.Function of Ikaros as a tumor suppressor in B cell acute lymphoblastic leukemiaAdvances in the Biology of Acute Lymphoblastic Leukemia-From Genomics to the ClinicIKZF1 deletion is an independent predictor of outcome in pediatric acute lymphoblastic leukemia treated according to the ALL-BFM 2000 protocol.Breakpoint-specific multiplex polymerase chain reaction allows the detection of IKZF1 intragenic deletions and minimal residual disease monitoring in B-cell precursor acute lymphoblastic leukemia.Genes commonly deleted in childhood B-cell precursor acute lymphoblastic leukemia: association with cytogenetics and clinical features.IKZF1 deletion is associated with a poor outcome in pediatric B-cell precursor acute lymphoblastic leukemia in Japan.What is the relevance of Ikaros gene deletions as a prognostic marker in pediatric Philadelphia-negative B-cell precursor acute lymphoblastic leukemia?Independent prognostic value of BCR-ABL1-like signature and IKZF1 deletion, but not high CRLF2 expression, in children with B-cell precursor ALL.Cytogenetic and molecular predictors of outcome in acute lymphocytic leukemia: recent developments.Ikaros and leukaemia.Genomics in acute lymphoblastic leukaemia: insights and treatment implications.Machine learning applications for prediction of relapse in childhood acute lymphoblastic leukemia.Conserved IKAROS-regulated genes associated with B-progenitor acute lymphoblastic leukemia outcome.Minimal Residual Disease in Acute Lymphoblastic Leukemia: How to Recognize and Treat It.Molecular profiling of gene copy number abnormalities in key regulatory genes in high-risk B-lineage acute lymphoblastic leukemia: frequency and their association with clinicopathological findings in Indian patients.Effect of IKZF1 deletions on signal transduction pathways in Philadelphia chromosome negative pediatric B-cell precursor acute lymphoblastic leukemia (BCP-ALL).Newly diagnosed acute lymphoblastic leukemia in China (II): prognosis related to genetic abnormalities in a series of 1091 cases.Absence of biallelic TCRγ deletion predicts induction failure and poorer outcomes in childhood T-cell acute lymphoblastic leukemia.IKZF1 deletions predict a poor prognosis in children with B-cell progenitor acute lymphoblastic leukemia: a multicenter analysis in Taiwan.Transcriptome Analysis of Minimal Residual Disease in Subtypes of Pediatric B Cell Acute Lymphoblastic Leukemia.Prognostic value of rare IKZF1 deletion in childhood B-cell precursor acute lymphoblastic leukemia: an international collaborative study.IKZF1 deletion is an independent prognostic marker in childhood B-cell precursor acute lymphoblastic leukemia, and distinguishes patients benefiting from pulses during maintenance therapy: results of the EORTC Children's Leukemia Group study 58951.
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Integrated use of minimal residual disease classification and IKZF1 alteration status accurately predicts 79% of relapses in pediatric acute lymphoblastic leukemia.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
2010年學術文章
@zh
2010年學術文章
@zh-hant
name
Integrated use of minimal resi ...... acute lymphoblastic leukemia.
@en
Integrated use of minimal resi ...... acute lymphoblastic leukemia.
@nl
type
label
Integrated use of minimal resi ...... acute lymphoblastic leukemia.
@en
Integrated use of minimal resi ...... acute lymphoblastic leukemia.
@nl
prefLabel
Integrated use of minimal resi ...... acute lymphoblastic leukemia.
@en
Integrated use of minimal resi ...... acute lymphoblastic leukemia.
@nl
P2093
P2860
P356
P1433
P1476
Integrated use of minimal resi ...... acute lymphoblastic leukemia.
@en
P2093
A Geurts van Kessel
A J Veerman
E Waanders
J J M van Dongen
P M Hoogerbrugge
R P Kuiper
S V van Reijmersdal
V H J van der Velden
P2860
P2888
P304
P356
10.1038/LEU.2010.275
P577
2010-11-19T00:00:00Z
P5875
P6179
1003812786