The TLR1/2 agonist PAM(3)CSK(4) instructs commitment of human hematopoietic stem cells to a myeloid cell fate. - Wikidata - wikimedia - TriplyDB

The TLR1/2 agonist PAM(3)CSK(4) instructs commitment of human hematopoietic stem cells to a myeloid cell fate.

The TLR1/2 agonist PAM(3)CSK(4) instructs commitment of human hematopoietic stem cells to a myeloid cell fate.

http://www.wikidata.org/entity/Q39819090

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Deregulation of innate immune and inflammatory signaling in myelodysplastic syndromes TLRs control hematopoiesis during infection Modulation of bleomycin-induced lung fibrosis by pegylated hyaluronidase and dopamine receptor antagonist in mice The Role of Toll-Like Receptors in Hematopoietic Malignancies Impact of Viral Infections on Hematopoiesis: From Beneficial to Detrimental Effects on Bone Marrow Output Candida albicans induces selective development of macrophages and monocyte derived dendritic cells by a TLR2 dependent signalling Toll-like receptor alterations in myelodysplastic syndrome Hematopoiesis in steady-state versus stress: self-renewal, lineage fate choice, and the conversion of danger signals into cytokine signals in hematopoietic stem cells Endothelial cells translate pathogen signals into G-CSF-driven emergency granulopoiesis.A novel inflammatory pathway mediating rapid hepcidin-independent hypoferremia.TLR2-deficiency of cKit+ bone marrow cells is associated with augmented potency to stimulate angiogenic processes.Overexpression of miR-125a in myelodysplastic syndrome CD34+ cells modulates NF-κB activation and enhances erythroid differentiation arrest Cutting Edge: Hematopoietic Stem Cell Expansion and Common Lymphoid Progenitor Depletion Require Hematopoietic-Derived, Cell-Autonomous TLR4 in a Model of Chronic Endotoxin.Regulation of stress-induced hematopoiesis Lineage switching in acute leukemias: a consequence of stem cell plasticity?Transcriptome Analysis of Long Noncoding RNAs in Toll-Like Receptor 3-Activated Mesenchymal Stem Cells.Hematopoietic stem and multipotent progenitor cells produce IL-17, IL-21 and other cytokines in response to TLR signals associated with late apoptotic products and augment memory Th17 and Tc17 cells in the bone marrow of normal and lupus mice The function of hematopoietic stem cells is altered by both genetic and inflammatory factors in lupus mice.Identification of early myeloid progenitors as immunosuppressive cells.TLR stimulation of bone marrow lymphoid precursors from childhood acute leukemia modifies their differentiation potentials.Induction of myelodysplasia by myeloid-derived suppressor cells.Hematopoiesis sculpted by pathogens: Toll-like receptors and inflammatory mediators directly activate stem cells.Regulation of hematopoietic stem cell activity by inflammation.The Transcription Factor ARID3a Is Important for In Vitro Differentiation of Human Hematopoietic Progenitors.Toll-like receptor signaling in hematopoietic homeostasis and the pathogenesis of hematologic diseases.Direct Toll-like receptor-mediated stimulation of hematopoietic stem and progenitor cells occurs in vivo and promotes differentiation toward macrophages.Systemic TLR2 agonist exposure regulates hematopoietic stem cells via cell-autonomous and cell-non-autonomous mechanisms.α-Toxin Regulates Local Granulocyte Expansion from Hematopoietic Stem and Progenitor Cells in Staphylococcus aureus-Infected Wounds.Lentiviral vectors escape innate sensing but trigger p53 in human hematopoietic stem and progenitor cells.Cutting Edge: Direct Sensing of TLR7 Ligands and Type I IFN by the Common Myeloid Progenitor Promotes mTOR/PI3K-Dependent Emergency Myelopoiesis.Chronic Inflammation in Immune Aging: Role of Pattern Recognition Receptor Crosstalk with the Telomere Complex?Hematopoietic stem and progenitor cells as effectors in innate immunity Membrane-bound IL-15 stimulation on peripheral blood natural kiler progenitors leads to the generation of an adherent subset co-expressing dendritic cells and natural kiler functional markers.Imiquimod inhibits growth and induces differentiation of myeloid leukemia cell lines.Bone marrow lympho-myeloid malfunction in obesity requires precursor cell-autonomous TLR4.LPS-stimulated human bone marrow stroma cells support myeloid cell development and progenitor cell maintenance.Toll-like receptor 3 regulates cord blood-derived endothelial cell function in vitro and in vivo.Toll-like receptor-mediated eosinophil-basophil differentiation: autocrine signalling by granulocyte-macrophage colony-stimulating factor in cord blood haematopoietic progenitors.Understanding the Cellular Origin of the Mononuclear Phagocyte System Sheds Light on the Myeloid Postulate of Immune Paralysis in Sepsis.Systemic Candidiasis and TLR2 Agonist Exposure Impact the Antifungal Response of Hematopoietic Stem and Progenitor Cells

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The TLR1/2 agonist PAM(3)CSK(4) instructs commitment of human hematopoietic stem cells to a myeloid cell fate.

http://www.wikidata.org/entity/Q39819090

description

2009 nî lūn-bûn

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2009年の論文

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2009年学术文章

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2009年学术文章

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name

The TLR1/2 agonist PAM

@nl

The TLR1/2 agonist PAM(3)CSK(4 ...... cells to a myeloid cell fate.

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type

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The TLR1/2 agonist PAM

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The TLR1/2 agonist PAM(3)CSK(4 ...... cells to a myeloid cell fate.

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prefLabel

The TLR1/2 agonist PAM

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The TLR1/2 agonist PAM(3)CSK(4 ...... cells to a myeloid cell fate.

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P2860

Commitment to the B-lymphoid lineage depends on the transcription factor Pax5

Erythroid differentiation in chimaeric mice blocked by a targeted mutation in the gene for transcription factor GATA-1

Contingent gene regulatory networks and B cell fate specification

Stepwise reprogramming of B cells into macrophages.

Neutrophil kinetics in acute infection

Prospective isolation of human clonogenic common myeloid progenitors.

Isolation and characterization of human myeloid progenitor populations--TpoR as discriminator between common myeloid and megakaryocyte/erythroid progenitors.

Long-term culture system for selective growth of human B-cell progenitors.

Hematopoietic cytokines, transcription factors and lineage commitment.

Toll-like receptors on hematopoietic progenitor cells stimulate innate immune system replenishment

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10.1038/LEU.2009.155

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