Selection and growth regulation of genetically modified cells with hapten-specific antibody/receptor tyrosine kinase chimera.
about
A novel platform for antibody library selection in mammalian cells based on a growth signalobody.Domain structure of growth signalobodies critically affects the outcome of antibody library selection.Growth signalobody selects functional intrabodies in the mammalian cytoplasm.S-Fms signalobody enhances myeloid cell growth and migration.Antigen-responsive regulation of Cell motility and migration via the signalobodies based on c-Fms and c-Mpl.Quantitative control of intracellular signaling activity through chimeric receptors incorporating multiple identical tyrosine motifs.Construction of unnatural heterodimeric receptors based on IL-2 and IL-6 receptor subunits.Activation of target signal transducers utilizing chimeric receptors with signaling-molecule binding motifs.Construction of antibody/insulin receptor chimera for growth induction of mammalian cellsCell-Surface Expression Levels Are Important for Fine-Tuning the Performance of Receptor Tyrosine Kinase-Based Signalobodies.Cell fate conversion by conditionally switching the signal-transducing domain of signalobodies.Receptor clustering and activation by multivalent interaction through recognition peptides presented on exosomes.Signal transduction using an artificial receptor system that undergoes dimerization upon addition of a bivalent leucine-zipper ligand.
P2860
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P2860
Selection and growth regulation of genetically modified cells with hapten-specific antibody/receptor tyrosine kinase chimera.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh
2009年學術文章
@zh-hant
name
Selection and growth regulatio ...... eptor tyrosine kinase chimera.
@en
Selection and growth regulatio ...... eptor tyrosine kinase chimera.
@nl
type
label
Selection and growth regulatio ...... eptor tyrosine kinase chimera.
@en
Selection and growth regulatio ...... eptor tyrosine kinase chimera.
@nl
prefLabel
Selection and growth regulatio ...... eptor tyrosine kinase chimera.
@en
Selection and growth regulatio ...... eptor tyrosine kinase chimera.
@nl
P50
P356
P1476
Selection and growth regulatio ...... ceptor tyrosine kinase chimera
@en
P2093
Kento Tanaka
P2860
P304
P356
10.1002/BTPR.185
P577
2009-07-01T00:00:00Z