Developmental control of CaV1.2 L-type calcium channel splicing by Fox proteins.
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RNA protein interaction in neuronsThe splicing regulator Rbfox2 is required for both cerebellar development and mature motor functionRbfox1 downregulation and altered calpain 3 splicing by FRG1 in a mouse model of Facioscapulohumeral muscular dystrophy (FSHD)NeuN/Rbfox3 nuclear and cytoplasmic isoforms differentially regulate alternative splicing and nonsense-mediated decay of Rbfox2RNA splicing regulated by RBFOX1 is essential for cardiac function in zebrafish.Role of the cytoplasmic isoform of RBFOX1/A2BP1 in establishing the architecture of the developing cerebral cortex.Autoregulation of Fox protein expression to produce dominant negative splicing factorsCalcium Channel CaVα₁ Splice Isoforms - Tissue Specificity and Drug Action.Experimental and Computational Considerations in the Study of RNA-Binding Protein-RNA InteractionsRegulation of the mutually exclusive exons 8a and 8 in the CaV1.2 calcium channel transcript by polypyrimidine tract-binding protein.Fox-1 family of RNA-binding proteins.The splicing regulator Rbfox1 (A2BP1) controls neuronal excitation in the mammalian brain.Alternative splicing generates a novel truncated Cav1.2 channel in neonatal rat heart.RBFOX2 promotes protein 4.1R exon 16 selection via U1 snRNP recruitment.Mechanisms of activation and repression by the alternative splicing factors RBFOX1/2.Alternative splicing converts STIM2 from an activator to an inhibitor of store-operated calcium channelsRbfox proteins regulate alternative splicing of neuronal sodium channel SCN8ACACNA1C (Cav1.2) in the pathophysiology of psychiatric diseaseExpression of Calcium Channel Subunit Variants in Small Mesenteric Arteries of WKY and SHRAlternative splicing: functional diversity among voltage-gated calcium channels and behavioral consequences.Aberrant Splicing Promotes Proteasomal Degradation of L-type CaV1.2 Calcium Channels by Competitive Binding for CaVβ Subunits in Cardiac Hypertrophy.Linker flexibility of IVS3-S4 loops modulates voltage-dependent activation of L-type Ca2+ channels.HITS-CLIP and integrative modeling define the Rbfox splicing-regulatory network linked to brain development and autism.Multilayered regulation of cardiac ion channels.Control of neuronal voltage-gated calcium ion channels from RNA to protein.L-type CaV1.2 calcium channels: from in vitro findings to in vivo function.Muscle weakness in myotonic dystrophy associated with misregulated splicing and altered gating of Ca(V)1.1 calcium channel.The determinants of alternative RNA splicing in human cells.Transcriptional regulation of voltage-gated Ca2+ channels.An inducible change in Fox-1/A2BP1 splicing modulates the alternative splicing of downstream neuronal target exons.Rbfox Proteins Regulate Splicing as Part of a Large Multiprotein Complex LASR.Novel Rbfox2 isoforms associated with alternative exon usage in rat cortex and suprachiasmatic nucleus.Developmental expression mapping of a gene implicated in multiple neurodevelopmental disorders, A2bp1 (Fox1).Quaking and PTB control overlapping splicing regulatory networks during muscle cell differentiation.Exclusion of alternative exon 33 of CaV1.2 calcium channels in heart is proarrhythmogenic.Splicing Activation by Rbfox Requires Self-Aggregation through Its Tyrosine-Rich Domain.Alternative Splicing of L-type CaV1.2 Calcium Channels: Implications in Cardiovascular Diseases.Neuron-specific alternative splicing of transcriptional machineries: Implications for neurodevelopmental disorders.Characterization of CaV1.2 exon 33 heterozygous knockout mice and negative correlation between Rbfox1 and CaV1.2 exon 33 expressions in human heart failure.
P2860
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P2860
Developmental control of CaV1.2 L-type calcium channel splicing by Fox proteins.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh
2009年學術文章
@zh-hant
name
Developmental control of CaV1.2 L-type calcium channel splicing by Fox proteins.
@en
Developmental control of CaV1.2 L-type calcium channel splicing by Fox proteins.
@nl
type
label
Developmental control of CaV1.2 L-type calcium channel splicing by Fox proteins.
@en
Developmental control of CaV1.2 L-type calcium channel splicing by Fox proteins.
@nl
prefLabel
Developmental control of CaV1.2 L-type calcium channel splicing by Fox proteins.
@en
Developmental control of CaV1.2 L-type calcium channel splicing by Fox proteins.
@nl
P2093
P2860
P356
P1476
Developmental control of CaV1.2 L-type calcium channel splicing by Fox proteins.
@en
P2093
Douglas L Black
Julia Nikolic
Sika Zheng
Zhen Zhi Tang
P2860
P304
P356
10.1128/MCB.00608-09
P407
P577
2009-06-29T00:00:00Z