Evidence for the generation of active oxygen by isoniazid treatment of extracts of Mycobacterium tuberculosis H37Ra.
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Isonicotinic Acid Hydrazide Conversion to Isonicotinyl-NAD by Catalase-peroxidasesIn vitro activity of a novel antimycobacterial compound, N-octanesulfonylacetamide, and its effects on lipid and mycolic acid synthesisOxidative stress response and its role in sensitivity to isoniazid in mycobacteria: characterization and inducibility of ahpC by peroxides in Mycobacterium smegmatis and lack of expression in M. aurum and M. tuberculosisAn in vitro model for sequential study of shiftdown of Mycobacterium tuberculosis through two stages of nonreplicating persistenceOverexpression, purification, and characterization of the catalase-peroxidase KatG from Mycobacterium tuberculosisCrystal structure of Mycobacterium tuberculosis catalase-peroxidaseMechanisms of action of isoniazidMycobacterial Cultures Contain Cell Size and Density Specific Sub-populations of Cells with Significant Differential Susceptibility to Antibiotics, Oxidative and Nitrite StressEnzyme-catalyzed mechanism of isoniazid activation in class I and class III peroxidases.Interactions of OxyR with the promoter region of the oxyR and ahpC genes from Mycobacterium leprae and Mycobacterium tuberculosis.Molecular basis for the exquisite sensitivity of Mycobacterium tuberculosis to isoniazidDetection of a novel catalase in extracts of Mycobacterium avium and Mycobacterium intracellulareRole of superoxide in catalase-peroxidase-mediated isoniazid action against mycobacteria.Oxidative stress increases susceptibility of Mycobacterium tuberculosis to isoniazid.Antimicrobial agent resistance in mycobacteria: molecular genetic insights.Characterization of the katG gene encoding a catalase-peroxidase required for the isoniazid susceptibility of Mycobacterium tuberculosis.Molecular and physiological effects of mycobacterial oxyR inactivation.Use of site-directed mutagenesis to probe the structure, function and isoniazid activation of the catalase/peroxidase, KatG, from Mycobacterium tuberculosis.Isoniazid induces its own resistance in nonreplicating Mycobacterium tuberculosis.Purification and characterization of the Mycobacterium smegmatis catalase-peroxidase involved in isoniazid activation.Synthesis, characterisation and antitubercular activities of a series of pyruvate-containing aroylhydrazones and their Cu-complexes.Probing the function of Mycobacterium tuberculosis catalase-peroxidase by site-directed mutagenesis.Mutation of katG in a clinical isolate of Mycobacterium tuberculosis: effects on catalase-peroxidase for isoniazid activation.The extreme sensitivity of Mycobacterium tuberculosis to the front-line antituberculosis drug isoniazid.Missense mutations in the catalase-peroxidase gene, katG, are associated with isoniazid resistance in Mycobacterium tuberculosis.Update of Antitubercular Prodrugs from a Molecular Perspective: Mechanisms of Action, Bioactivation Pathways, and Associated Resistance.Effect of inhA and katG on isoniazid resistance and virulence of Mycobacterium bovis.Biocompatible citric acid-coated iron oxide nanoparticles to enhance the activity of first-line anti-TB drugs inMycobacterium smegmatis
P2860
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P2860
Evidence for the generation of active oxygen by isoniazid treatment of extracts of Mycobacterium tuberculosis H37Ra.
description
1985 nî lūn-bûn
@nan
1985年の論文
@ja
1985年学术文章
@wuu
1985年学术文章
@zh-cn
1985年学术文章
@zh-hans
1985年学术文章
@zh-my
1985年学术文章
@zh-sg
1985年學術文章
@yue
1985年學術文章
@zh
1985年學術文章
@zh-hant
name
Evidence for the generation of ...... obacterium tuberculosis H37Ra.
@en
Evidence for the generation of ...... obacterium tuberculosis H37Ra.
@nl
type
label
Evidence for the generation of ...... obacterium tuberculosis H37Ra.
@en
Evidence for the generation of ...... obacterium tuberculosis H37Ra.
@nl
prefLabel
Evidence for the generation of ...... obacterium tuberculosis H37Ra.
@en
Evidence for the generation of ...... obacterium tuberculosis H37Ra.
@nl
P2093
P2860
P356
P1476
Evidence for the generation of ...... obacterium tuberculosis H37Ra.
@en
P2093
Bowman BU Jr
Ottolenghi AC
P2860
P304
P356
10.1128/AAC.27.3.404
P407
P577
1985-03-01T00:00:00Z