Targeting adrenomedullin receptors with systemic delivery of neutralizing antibodies inhibits tumor angiogenesis and suppresses growth of human tumor xenografts in mice.
about
Comparative expression study of the endo-G protein coupled receptor (GPCR) repertoire in human glioblastoma cancer stem-like cells, U87-MG cells and non malignant cells of neural origin unveils new potential therapeutic targetsTumor-expressed adrenomedullin accelerates breast cancer bone metastasis.Adrenomedullin as a therapeutic target in angiogenesis.In vitro gene regulatory networks predict in vivo function of liverAn angiogenic role for adrenomedullin in choroidal neovascularization.Adrenomedullin Function in Vascular Endothelial Cells: Insights from Genetic Mouse Models.Macrophages in tumor microenvironments and the progression of tumors.Expression of adrenomedullin in human colorectal tumors and its role in cell growth and invasion in vitro and in xenograft growth in vivo.Prevention of Bone Loss in a Model of Postmenopausal Osteoporosis through Adrenomedullin Inhibition.Oncogenic epithelial cell-derived exosomes containing Rac1 and PAK2 induce angiogenesis in recipient endothelial cells.The G-protein-coupled receptor CLR is upregulated in an autocrine loop with adrenomedullin in clear cell renal cell carcinoma and associated with poor prognosis.Adrenomedullin is a therapeutic target in colorectal cancer.Adrenomedullin and adrenotensin regulate collagen synthesis and proliferation in pulmonary arterial smooth muscle cellsAdrenomedullin promotes the growth of pancreatic ductal adenocarcinoma through recruitment of myelomonocytic cells.Stromal fibroblasts present in breast carcinomas promote tumor growth and angiogenesis through adrenomedullin secretionAdrenomedullin and tumour microenvironment.Elevated expression of adrenomedullin is correlated with prognosis and disease severity in osteosarcoma.Adrenomedullin blockade induces regression of tumor neovessels through interference with vascular endothelial-cadherin signalling.The Role of the Calcitonin Peptide Family in Prostate Cancer and Bone Metastasis.Adrenomedullin as a growth and cell fate regulatory factor for adult neural stem cells.Small molecules related to adrenomedullin reduce tumor burden in a mouse model of colitis-associated colon cancer.Role of different inflammatory and tumor biomarkers in the development of ulcerative colitis-associated carcinogenesis.Overexpression of adrenomedullin protects mesenchymal stem cells against hypoxia and serum deprivation‑induced apoptosis via the Akt/GSK3β and Bcl‑2 signaling pathways.
P2860
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P2860
Targeting adrenomedullin receptors with systemic delivery of neutralizing antibodies inhibits tumor angiogenesis and suppresses growth of human tumor xenografts in mice.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh
2009年學術文章
@zh-hant
name
Targeting adrenomedullin recep ...... uman tumor xenografts in mice.
@en
Targeting adrenomedullin recep ...... uman tumor xenografts in mice.
@nl
type
label
Targeting adrenomedullin recep ...... uman tumor xenografts in mice.
@en
Targeting adrenomedullin recep ...... uman tumor xenografts in mice.
@nl
prefLabel
Targeting adrenomedullin recep ...... uman tumor xenografts in mice.
@en
Targeting adrenomedullin recep ...... uman tumor xenografts in mice.
@nl
P2093
P50
P356
P1433
P1476
Targeting adrenomedullin recep ...... uman tumor xenografts in mice.
@en
P2093
Caroline Berenguer
Christine Delfino
Christophe Dussert
François Grisoli
Itidal Kaafarani
Kamel Mabrouk
Olivier Chinot
Philippe Metellus
Pierre-Marie Martin
Samantha Fernandez-Sauze
P304
P356
10.1096/FJ.08-127852
P407
P577
2009-06-22T00:00:00Z