Zinc binding in pestivirus N(pro) is required for interferon regulatory factor 3 interaction and degradation.
about
Immune Responses Against Classical Swine Fever Virus: Between Ignorance and LunacyCrystal Structures of the Viral Protease Npro Imply Distinct Roles for the Catalytic Water in CatalysisThe Structure of Classical Swine Fever Virus Npro: A Novel Cysteine Autoprotease and Zinc-Binding Protein Involved in Subversion of Type I Interferon InductionHost factors that interact with the pestivirus N-terminal protease, Npro, are components of the ribonucleoprotein complexClassical swine fever virus N(pro) limits type I interferon induction in plasmacytoid dendritic cells by interacting with interferon regulatory factor 7.Viral hijacking of the host ubiquitin system to evade interferon responses.The pestivirus N terminal protease N(pro) redistributes to mitochondria and peroxisomes suggesting new sites for regulation of IRF3 by N(pro.).Rotavirus antagonism of the innate immune responseAnalysis of a pair of END+ and END- viruses derived from the same bovine viral diarrhea virus stock reveals the amino acid determinants in Npro responsible for inhibition of type I interferon production.Viral tricks to grid-lock the type I interferon system.Live Cell Reporter Systems for Positive-Sense Single Strand RNA Viruses.Npro of classical swine fever virus contributes to pathogenicity in pigs by preventing type I interferon induction at local replication sites.IRF3 inhibition by rotavirus NSP1 is host cell and virus strain dependent but independent of NSP1 proteasomal degradation.RNA-virus proteases counteracting host innate immunity.Pestivirus Npro Directly Interacts with Interferon Regulatory Factor 3 Monomer and Dimer.
P2860
Q26776096-8FE58C0D-FAEB-4990-AF95-E604A64F8670Q27677976-E155195F-D947-4AC8-80EA-271CC681C325Q27680413-30C81DC8-5723-4C0A-8685-EF2EB2F1ABD0Q28114880-14ECD95E-4EAD-4832-A374-EA8DC6C89C24Q33934870-ABC1955F-3FAA-4558-8100-BBE757CF92A0Q34130663-120540A9-E5DB-4C1B-9BCB-ADE7A3DD8AA7Q35097600-F81988DD-E752-4D9B-A697-D2351C4F779CQ35260141-129C178F-7CF4-475B-B48D-5C2833DE57ABQ35774566-35206ECA-0CEE-414D-BEE4-2E45AC89635AQ37764230-D29F0F72-685D-44FC-97DB-E55D984B961FQ38686227-41ED43E5-2518-4244-A389-C6299B77775AQ39003275-93B00F40-E0E8-4CD1-9D62-D49408AF9FA0Q39816481-6CF4D45C-1984-4B27-BBB4-8888BDE0BE95Q40066626-667C6101-B0C8-47A2-9B09-C5ED7DE004E7Q40100158-B8242087-94C4-4863-A258-EA0B05B8C2D6
P2860
Zinc binding in pestivirus N(pro) is required for interferon regulatory factor 3 interaction and degradation.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh
2009年學術文章
@zh-hant
name
Zinc binding in pestivirus N
@nl
Zinc binding in pestivirus N(p ...... 3 interaction and degradation.
@en
type
label
Zinc binding in pestivirus N
@nl
Zinc binding in pestivirus N(p ...... 3 interaction and degradation.
@en
prefLabel
Zinc binding in pestivirus N
@nl
Zinc binding in pestivirus N(p ...... 3 interaction and degradation.
@en
P2093
P1476
Zinc binding in pestivirus N(p ...... 3 interaction and degradation
@en
P2093
Ana R Fiebach
Jon-Duri Tratschin
Keerthi Gottipati
Kyung H Choi
Purvi Patel
V M Sadagopa Ramanujam
P304
P356
10.1016/J.JMB.2009.06.040
P407
P577
2009-06-21T00:00:00Z