Functional rescue of beta-adrenoceptor dimerization and trafficking by pharmacological chaperones.
about
Cys-27 variant of human δ-opioid receptor modulates maturation and cell surface delivery of Phe-27 variant via heteromerizationPharmacological chaperoning: a primer on mechanism and pharmacologyCrystal structure of oligomeric β1-adrenergic G protein–coupled receptors in ligand-free basal stateAccurate protein structure annotation through competitive diffusion of enzymatic functions over a network of local evolutionary similaritiesSeparation of recombination and SOS response in Escherichia coli RecA suggests LexA interaction sitesAssessing the effect of dynamics on the closed-loop protein-folding hypothesisEvolution-guided discovery and recoding of allosteric pathway specificity determinants in psychoactive bioamine receptors.Mutational analysis of threonine 402 adjacent to the GXXXG dimerization motif in transmembrane segment 1 of ABCG2.Evolution: a guide to perturb protein function and networksGABA acts as a ligand chaperone in the early secretory pathway to promote cell surface expression of GABAA receptorsSequence and structure continuity of evolutionary importance improves protein functional site discovery and annotation.Determinants of endogenous ligand specificity divergence among metabotropic glutamate receptorsStructurally distinct ligands rescue biogenesis defects of the KATP channel complex via a converging mechanism.Neuronal gamma-aminobutyric acid (GABA) type A receptors undergo cognate ligand chaperoning in the endoplasmic reticulum by endogenous GABA.The rhodopsin-transducin complex houses two distinct rhodopsin moleculesThe prevalence, maintenance, and relevance of G protein-coupled receptor oligomerizationEvolutionary trace for prediction and redesign of protein functional sites.Sensitive and high resolution localization and tracking of membrane proteins in live cells with BRET.GPCR: G protein complexes--the fundamental signaling assembly.Structure and function of G protein-coupled receptor oligomers: implications for drug discovery.Pharmacological folding chaperones act as allosteric ligands of Frizzled4.Homodimerization as a molecular switch between low and high efficiency PrP C cell surface delivery and neuroprotective activity.Pathomechanistic characterization of two exonic L1CAM variants located in trans in an obligate carrier of X-linked hydrocephalus.Ligand regulation of the quaternary organization of cell surface M3 muscarinic acetylcholine receptors analyzed by fluorescence resonance energy transfer (FRET) imaging and homogeneous time-resolved FRETCognate Ligand Chaperoning: a Novel Mechanism for the Post-translational Regulation of Neurotransmitter Receptor Biogenesis.Pharmacological Chaperones: Beyond Conformational Disorders.Pharmacoperones for Misfolded Gonadotropin Receptors.Rab7 palmitoylation is required for efficient endosome-to-TGN trafficking.Adverse Effects on β-Adrenergic Receptor Coupling: Ischemic Postconditioning Failed to Preserve Long-Term Cardiac Function.A novel small molecule chaperone of rod opsin and its potential therapy for retinal degeneration.CrossTalk proposal: Weighing the evidence for Class A GPCR dimers, the evidence favours dimersCarvedilol Prevents Redox Inactivation of Cardiomyocyte Β-Adrenergic Receptors
P2860
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P2860
Functional rescue of beta-adrenoceptor dimerization and trafficking by pharmacological chaperones.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh
2009年學術文章
@zh-hant
name
Functional rescue of beta-adre ...... by pharmacological chaperones.
@en
Functional rescue of beta-adre ...... by pharmacological chaperones.
@nl
type
label
Functional rescue of beta-adre ...... by pharmacological chaperones.
@en
Functional rescue of beta-adre ...... by pharmacological chaperones.
@nl
prefLabel
Functional rescue of beta-adre ...... by pharmacological chaperones.
@en
Functional rescue of beta-adre ...... by pharmacological chaperones.
@nl
P2860
P50
P1433
P1476
Functional rescue of beta-adre ...... by pharmacological chaperones.
@en
P2093
P2860
P304
P356
10.1111/J.1600-0854.2009.00932.X
P577
2009-06-09T00:00:00Z