High efficacy of panobinostat towards human gastrointestinal stromal tumors in a xenograft mouse model.
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Emerging Agents for the Treatment of Advanced, Imatinib-Resistant Gastrointestinal Stromal Tumors: Current Status and Future DirectionsA potent combination of the novel PI3K Inhibitor, GDC-0941, with imatinib in gastrointestinal stromal tumor xenografts: long-lasting responses after treatment withdrawal.Phase I study of panobinostat and imatinib in patients with treatment-refractory metastatic gastrointestinal stromal tumorsA phase I, pharmacokinetic, and pharmacodynamic study of panobinostat, an HDAC inhibitor, combined with erlotinib in patients with advanced aerodigestive tract tumorsCharacterization and assessment of the sensitivity and resistance of a newly established human gastrointestinal stromal tumour xenograft model to treatment with tyrosine kinase inhibitors.Pazopanib, a Receptor Tyrosine Kinase Inhibitor, Suppresses Tumor Growth through Angiogenesis in Dedifferentiated Liposarcoma Xenograft ModelsTherapeutic Efficacy Assessment of CK6, a Monoclonal KIT Antibody, in a Panel of Gastrointestinal Stromal Tumor Xenograft Models.Beyond standard therapy: drugs under investigation for the treatment of gastrointestinal stromal tumor.Targeting triple-negative breast cancer cells with the histone deacetylase inhibitor panobinostat.Sustained Low-Dose Treatment with the Histone Deacetylase Inhibitor LBH589 Induces Terminal Differentiation of Osteosarcoma CellsProfile of panobinostat and its potential for treatment in solid tumors: an update.Inhibiting histone deacetylases suppresses glucose metabolism and hepatocellular carcinoma growth by restoring FBP1 expression.Implications of mutational analysis for the management of patients with gastrointestinal stromal tumors and the application of targeted therapies.Molecular basis for primary and secondary tyrosine kinase inhibitor resistance in gastrointestinal stromal tumorHistone acetyltransferases and deacetylases: molecular and clinical implications to gastrointestinal carcinogenesis.Epigenetics in gastrointestinal stromal tumors: clinical implications and potential therapeutic perspectives.Panobinostat: first global approval.Effective Concentration of a Multikinase Inhibitor within Bone Marrow Correlates with In Vitro Cell Killing in Therapy-Resistant Chronic Myeloid Leukemia.The HSP90 inhibitor, AT13387, is effective against imatinib-sensitive and -resistant gastrointestinal stromal tumor models.Novel Insights into the Treatment of Imatinib-Resistant Gastrointestinal Stromal Tumors.Emerging drugs for the treatment of gastrointestinal stromal tumour.New targets and therapies for gastrointestinal stromal tumors.Promoting role of cholecystokinin 2 receptor (CCK2R) in gastrointestinal stromal tumour pathogenesis.
P2860
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P2860
High efficacy of panobinostat towards human gastrointestinal stromal tumors in a xenograft mouse model.
description
2009 nî lūn-bûn
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2009年の論文
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2009年学术文章
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2009年学术文章
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2009年学术文章
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2009年学术文章
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2009年學術文章
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name
High efficacy of panobinostat ...... rs in a xenograft mouse model.
@en
High efficacy of panobinostat ...... rs in a xenograft mouse model.
@nl
type
label
High efficacy of panobinostat ...... rs in a xenograft mouse model.
@en
High efficacy of panobinostat ...... rs in a xenograft mouse model.
@nl
prefLabel
High efficacy of panobinostat ...... rs in a xenograft mouse model.
@en
High efficacy of panobinostat ...... rs in a xenograft mouse model.
@nl
P2093
P50
P1476
High efficacy of panobinostat ...... rs in a xenograft mouse model.
@en
P2093
Cristiana Stefan
Kathleen Machiels
Peter Atadja
Steffen Fieuws
P304
P356
10.1158/1078-0432.CCR-08-2588
P407
P577
2009-06-09T00:00:00Z