Conjugation of 2-(1'-hexyloxyethyl)-2-devinylpyropheophorbide-a (HPPH) to carbohydrates changes its subcellular distribution and enhances photodynamic activity in vivo
about
Current applications of graphene oxide in nanomedicineChiral porphyrazine near-IR optical imaging agent exhibiting preferential tumor accumulation.Synthesis and in vitro evaluation of BBB permeability, tumor cell uptake, and cytotoxicity of a series of carboranylporphyrin conjugatesSynthesis and biological evaluation of a library of glycoporphyrin compounds.Substrate affinity of photosensitizers derived from chlorophyll-a: the ABCG2 transporter affects the phototoxic response of side population stem cell-like cancer cells to photodynamic therapy.Syntheses and cellular investigations of 17(3)-, 15(2)-, and 13(1)-amino acid derivatives of chlorin e(6).Promotion of Proapoptotic Signals by Lysosomal Photodamage.Imaging a photodynamic therapy photosensitizer in vivo with a time-gated fluorescence tomography system.Syntheses and cellular investigations of di-aspartate and aspartate-lysine chlorin e(6) conjugates.Advance in photosensitizers and light delivery for photodynamic therapyEfficacy of 2-(1-hexyloxyethyl)-2-devinyl pyropheophorbide-a in photodynamic therapy of human esophageal squamous cancer cellsPhotosensitizer loaded nano-graphene for multimodality imaging guided tumor photodynamic therapy.Peptide-based molecular beacons for cancer imaging and therapy.Human ABCG2: structure, function, and its role in multidrug resistance.Apoptosis and associated phenomena as a determinants of the efficacy of photodynamic therapy.Glycosyl-modified diporphyrins for in vitro and in vivo fluorescence imaging.Graphene-based nanomaterials: biological and medical applications and toxicity.In vitro cellular uptake and dimerization of signal transducer and activator of transcription-3 (STAT3) identify the photosensitizing and imaging-potential of isomeric photosensitizers derived from chlorophyll-a and bacteriochlorophyll-a.Cell-type selective phototoxicity achieved with chlorophyll-a derived photosensitizers in a co-culture system of primary human tumor and normal lung cells.Design features for optimization of tetrapyrrole macrocycles as antimicrobial and anticancer photosensitizers.Mechanistics and photo-energetics of macrocycles and photodynamic therapy: An overview of aspects to consider for research.Tumor targeting in photodynamic therapy. From glycoconjugated photosensitizers to glycodendrimeric one. Concept, design and properties.Conjugation of cRGD peptide to chlorophyll a based photosensitizer (HPPH) alters its pharmacokinetics with enhanced tumor-imaging and photosensitizing (PDT) efficacy.Synthesis of Tumor-avid Photosensitizer-Gd(III)DTPA conjugates: impact of the number of gadolinium units in T1/T2 relaxivity, intracellular localization, and photosensitizing efficacy.Interleukin-1α is the major alarmin of lung epithelial cells released during photodynamic therapy to induce inflammatory mediators in fibroblasts.Novel porphyrazine derivatives show promise for photodynamic therapy despite restrictions in hydrophilicity.Regioselective synthesis and photophysical and electrochemical studies of 20-substituted cyanine dye-purpurinimide conjugates: incorporation of Ni(II) into the conjugate enhances its tumor-uptake and fluorescence-imaging ability.
P2860
Q26783225-3BFEF927-D5D3-448A-8790-8A803610A3ABQ33667439-E57A2814-1B4B-425F-85F5-07D58A931BD3Q34061191-D2FF8584-8EBD-48F8-AD28-5B59D8847AF9Q34423462-ACCBDDCC-4F61-4BEE-9738-B048741DDAA3Q34472249-790BCBDE-C864-4534-9D81-18D3A3406654Q35523817-822DF100-7FC2-423A-B513-7E4E0999FB87Q35811913-210383F3-C85E-456A-AFA9-CE333570CFC6Q36051999-1E584C0D-6DCF-4907-B387-99EED1C8958DQ36431003-3158908C-E8DB-4DC0-9218-54350A42B898Q36609660-0B7C96BB-78CE-453A-9941-49A630C7B631Q37229356-389B03C0-DEF1-4B6B-B56B-F06C65A26C27Q37558853-E32E22CF-FBE4-49D7-8633-663E7451D4F4Q37695129-2567B5E5-1518-4739-843A-CAC4449531BBQ38003156-10A66144-A33B-40E8-B705-6B745DE643D7Q38307797-88C040E0-6BFE-4FC3-9822-FCFED8963D4DQ38315765-4B127C9F-71F7-4895-B8EA-80CA7505D0E7Q38561249-B9BB638E-3442-4011-A3E1-E6BDBC93E4E4Q38646915-730A0E65-F752-482B-BCDA-175AC5157879Q38810508-8227FC1C-62A0-45E4-A9FC-7054A55E6CE3Q39138260-A57039F6-4941-4B26-8521-E647D1969C65Q39138277-ACECA624-B827-4142-9FD3-336CA67B8755Q39351779-871F04FE-1C6E-4839-A638-165630896CD4Q39518754-49BEF5F4-8306-459B-AC13-1A0D513D419BQ39715385-D50AFD68-884F-442C-8BC5-1515444EDB98Q41319934-8F1A001F-F55B-421B-8D1C-ACCAD06B94CBQ46143068-DF16A791-8673-488C-8955-9CA862B3ABF1Q53336163-0993248D-3725-410F-B38B-AA07809C6FBF
P2860
Conjugation of 2-(1'-hexyloxyethyl)-2-devinylpyropheophorbide-a (HPPH) to carbohydrates changes its subcellular distribution and enhances photodynamic activity in vivo
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh
2009年學術文章
@zh-hant
name
Conjugation of 2-
@nl
Conjugation of 2-(1'-hexyloxye ...... photodynamic activity in vivo
@en
type
label
Conjugation of 2-
@nl
Conjugation of 2-(1'-hexyloxye ...... photodynamic activity in vivo
@en
prefLabel
Conjugation of 2-
@nl
Conjugation of 2-(1'-hexyloxye ...... photodynamic activity in vivo
@en
P2093
P2860
P356
P1476
Conjugation of 2-(1'-hexyloxye ...... photodynamic activity in vivo
@en
P2093
Barbara W Henderson
Carrie Batt
David A Bellnier
Erin Tracy
Heinz Baumann
Janet Morgan
Jennifer Jackson
Joseph R Missert
Ravindra K Pandey
Xiang Zheng
P2860
P304
P356
10.1021/JM9001617
P407
P577
2009-07-01T00:00:00Z