Cyclophilins contribute to Stat3 signaling and survival of multiple myeloma cells. - Wikidata - wikimedia - TriplyDB

Cyclophilins contribute to Stat3 signaling and survival of multiple myeloma cells.

Cyclophilins contribute to Stat3 signaling and survival of multiple myeloma cells.

http://www.wikidata.org/entity/Q39841617

about

From Drosophila to humans: reflections on the roles of the prolyl isomerases and chaperones, cyclophilins, in cell function and disease Stat1 activation attenuates IL-6 induced Stat3 activity but does not alter apoptosis sensitivity in multiple myeloma.Knockdown of CypA inhibits interleukin-8 (IL-8) and IL-8-mediated proliferation and tumor growth of glioblastoma cells through down-regulated NF-κB.Cyclophilin A (CypA) interacts with NF-κB subunit, p65/RelA, and contributes to NF-κB activation signaling.Targeting the cyclophilin domain of Ran-binding protein 2 (Ranbp2) with novel small molecules to control the proteostasis of STAT3, hnRNPA2B1 and M-opsin.Cyclophilin A (CypA) Plays Dual Roles in Regulation of Bone Anabolism and Resorption Cyclophilin A as a New Therapeutic Target for Hepatitis C Virus-induced Hepatocellular Carcinoma Low-salt diet and cyclosporine nephrotoxicity: changes in kidney cell metabolism.HAb18G/CD147 promotes pSTAT3-mediated pancreatic cancer development via CD44s.Increased expression of extracellular matrix metalloproteinase inducer (CD147) in multiple myeloma: role in regulation of myeloma cell proliferation Interaction of cyclophilin A with a novel binding protein, SR-25, and characterization of their expression pattern in Chinese hepatocellular carcinoma patients Differential loss of prolyl isomerase or chaperone activity of Ran-binding protein 2 (Ranbp2) unveils distinct physiological roles of its cyclophilin domain in proteostasis.Cyclophilin B supports Myc and mutant p53-dependent survival of glioblastoma multiforme cells.An overview of cyclophilins in human cancers.Cyclophilin A as a downstream effector of PI3K/Akt signalling pathway in multiple myeloma cells.Novel role for cyclophilin A in regulation of chondrogenic commitment and endochondral ossification.Secreted cyclophilin A mediates G1/S phase transition of cholangiocarcinoma cells via CD147/ERK1/2 pathway.Cyclophilin A Aggravates Collagen-Induced Arthritis via Promoting Classically Activated Macrophages.Proline isomerisation as a novel regulatory mechanism for p38MAPK activation and functions.Role of cyclophilin B in tumorigenesis and cisplatin resistance in hepatocellular carcinoma in humans.

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Cyclophilins contribute to Stat3 signaling and survival of multiple myeloma cells.

http://www.wikidata.org/entity/Q39841617

description

2009 nî lūn-bûn

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2009年の論文

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2009年学术文章

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2009年学术文章

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2009年学术文章

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2009年学术文章

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2009年学术文章

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2009年學術文章

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2009年學術文章

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2009年學術文章

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name

Cyclophilins contribute to Stat3 signaling and survival of multiple myeloma cells.

@en

Cyclophilins contribute to Stat3 signaling and survival of multiple myeloma cells.

@nl

type

label

Cyclophilins contribute to Stat3 signaling and survival of multiple myeloma cells.

@en

Cyclophilins contribute to Stat3 signaling and survival of multiple myeloma cells.

@nl

prefLabel

Cyclophilins contribute to Stat3 signaling and survival of multiple myeloma cells.

@en

Cyclophilins contribute to Stat3 signaling and survival of multiple myeloma cells.

@nl

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Cyclophilins contribute to Stat3 signaling and survival of multiple myeloma cells.

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A K Kretzschmar

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A Sinz

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C Blumert

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C Schiene-Fischer

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C V Clevenger

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F Horn

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G Fischer

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H Cvijic

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P2860

Cyclophilin B is a functional regulator of hepatitis C virus RNA polymerase

Point mutations in v-Myb disrupt a cyclophilin-catalyzed negative regulatory mechanism

BCL3 is induced by IL-6 via Stat3 binding to intronic enhancer HS4 and represses its own transcription

Regulation of the tyrosine kinase Itk by the peptidyl-prolyl isomerase cyclophilin A

The cyclophilins

A system for stable expression of short interfering RNAs in mammalian cells

Cyclophilin A and Ess1 interact with and regulate silencing by the Sin3-Rpd3 histone deacetylase.

Posttranslational regulation of IRF-4 activity by the immunophilin FKBP52

The prolyl isomerase Pin1 reveals a mechanism to control p53 functions after genotoxic insults

Differential activation of acute phase response factor/Stat3 and Stat1 via the cytoplasmic domain of the interleukin 6 signal transducer gp130. II. Src homology SH2 domains define the specificity of stat factor activation

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2784-2795

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10.1038/ONC.2009.142

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31

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19503092

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