Synthesis and biological activity of alpha-galactosyl ceramide KRN7000 and galactosyl (alpha1-->2) galactosyl ceramide.
about
CD169(+) macrophages present lipid antigens to mediate early activation of iNKT cells in lymph nodes.The stimulating adventure of KRN 7000.Asymmetric synthesis of D-ribo-phytosphingosine from 1-tetradecyne and (4-methoxyphenoxy)acetaldehyde.Lysosomal trafficking, antigen presentation, and microbial killing are controlled by the Arf-like GTPase Arl8bInnate and cytokine-driven signals, rather than microbial antigens, dominate in natural killer T cell activation during microbial infectionInvariant natural killer T cells recognize lipid self antigen induced by microbial danger signalsRegulation of the actin cytoskeleton by Rho kinase controls antigen presentation by CD1d.Saposins modulate human invariant Natural Killer T cells self-reactivity and facilitate lipid exchange with CD1d molecules during antigen presentation.New CD1d agonists: synthesis and biological activity of 6″-triazole-substituted α-galactosyl ceramides.Towards multivalent CD1d ligands: synthesis and biological activity of homodimeric α-galactosyl ceramide analogues.Synthesis and biological activity of alpha-L-fucosyl ceramides, analogues of the potent agonist, alpha-D-galactosyl ceramide KRN7000.Synthesis of C6''-modified α-C-GalCer analogues as mouse and human iNKT cell agonists.
P2860
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P2860
Synthesis and biological activity of alpha-galactosyl ceramide KRN7000 and galactosyl (alpha1-->2) galactosyl ceramide.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh
2009年學術文章
@zh-hant
name
Synthesis and biological activ ...... pha1-->2) galactosyl ceramide.
@en
Synthesis and biological activity of alpha-galactosyl ceramide KRN7000 and galactosyl
@nl
type
label
Synthesis and biological activ ...... pha1-->2) galactosyl ceramide.
@en
Synthesis and biological activity of alpha-galactosyl ceramide KRN7000 and galactosyl
@nl
prefLabel
Synthesis and biological activ ...... pha1-->2) galactosyl ceramide.
@en
Synthesis and biological activity of alpha-galactosyl ceramide KRN7000 and galactosyl
@nl
P2093
P2860
P50
P1476
Synthesis and biological activ ...... pha1-->2) galactosyl ceramide.
@en
P2093
Manfred Brigl
Michael B Brenner
Salil Garg
P2860
P304
P356
10.1016/J.BMCL.2009.05.095
P407
P577
2009-05-27T00:00:00Z