Distinct molecular requirements for activation or stabilization of soluble guanylyl cyclase upon haem oxidation-induced degradation.
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Pharmacology and Clinical Drug Candidates in Redox MedicineHeme-dependent and independent soluble guanylate cyclase activators and vasodilation.Fluorescence dequenching makes haem-free soluble guanylate cyclase detectable in living cellsThe amino-terminus of nitric oxide sensitive guanylyl cyclase α₁ does not affect dimerization but influences subcellular localizationChronic Activation of Heme Free Guanylate Cyclase Leads to Renal Protection in Dahl Salt-Sensitive Rats.Stimulation of soluble guanylyl cyclase protects against obesity by recruiting brown adipose tissueThe fibrate gemfibrozil is a NO- and haem-independent activator of soluble guanylyl cyclase: in vitro studies.Nitric oxide and heat shock protein 90 activate soluble guanylate cyclase by driving rapid change in its subunit interactions and heme content.Heme oxygenase-1 deficiency leads to alteration of soluble guanylate cyclase redox regulation.Soluble guanylate cyclase as an emerging therapeutic target in cardiopulmonary disease.Soluble guanylate cyclase: a new therapeutic target for pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension.Oxidation and loss of heme in soluble guanylyl cyclase from Manduca sexta.NOX1, 2, 4, 5: counting out oxidative stress.Soluble guanylate cyclase modulators blunt hyperoxia effects on calcium responses of developing human airway smooth muscle.Soluble guanylyl cyclase requires heat shock protein 90 for heme insertion during maturation of the NO-active enzyme.The soluble guanylyl cyclase activator bay 58-2667 selectively limits cardiomyocyte hypertrophy.Cardiovascular and pharmacological implications of haem-deficient NO-unresponsive soluble guanylate cyclase knock-in mice.Riociguat for the treatment of pulmonary hypertension.Regulation of sGC via hsp90, Cellular Heme, sGC Agonists, and NO: New Pathways and Clinical Perspectives.Hydrogen sulfide, an enhancer of vascular nitric oxide signaling: mechanisms and implications.Activation of haem-oxidized soluble guanylyl cyclase with BAY 60-2770 in human platelets lead to overstimulation of the cyclic GMP signaling pathway.Regulation of soluble guanylyl cyclase redox state by hydrogen sulfide.Platelet hyperaggregability in high-fat fed rats: a role for intraplatelet reactive-oxygen species production.Stimulators and activators of soluble guanylate cyclase for urogenital disorders.Influence of cinaciguat on gastrointestinal motility in apo-sGC mice.Cyclic GMP protects endothelial progenitors from oxidative stress.
P2860
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P2860
Distinct molecular requirements for activation or stabilization of soluble guanylyl cyclase upon haem oxidation-induced degradation.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
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2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
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2009年學術文章
@zh-hant
name
Distinct molecular requirement ...... oxidation-induced degradation.
@en
Distinct molecular requirement ...... oxidation-induced degradation.
@nl
type
label
Distinct molecular requirement ...... oxidation-induced degradation.
@en
Distinct molecular requirement ...... oxidation-induced degradation.
@nl
prefLabel
Distinct molecular requirement ...... oxidation-induced degradation.
@en
Distinct molecular requirement ...... oxidation-induced degradation.
@nl
P2093
P2860
P1476
Distinct molecular requirement ...... oxidation-induced degradation.
@en
P2093
H H H W Schmidt
J P Stasch
L S Hoffmann
P M Schmidt
S Schaefer
P2860
P304
P356
10.1111/J.1476-5381.2009.00263.X
P407
P577
2009-05-18T00:00:00Z