Ursolic acid triggers apoptosis and Bcl-2 downregulation in MCF-7 breast cancer cells.
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Natural Products for Chemoprevention of Breast Cancer"Ziziphus jujuba": A red fruit with promising anticancer activitiesThe therapeutic potential of RORγ modulators in the treatment of human diseaseSterol metabolism controls T(H)17 differentiation by generating endogenous RORγ agonistsIdentification of Tetraazacyclic Compounds as Novel Potent Inhibitors Antagonizing RORγt Activity and Suppressing Th17 Cell DifferentiationUrsolic acid-mediated changes in glycolytic pathway promote cytotoxic autophagy and apoptosis in phenotypically different breast cancer cells.Anticancer activity of 2α, 3α, 19β, 23β-Tetrahydroxyurs-12-en-28-oic acid (THA), a novel triterpenoid isolated from Sinojackia sarcocarpaUrsolic acid inhibits the initiation, progression of prostate cancer and prolongs the survival of TRAMP mice by modulating pro-inflammatory pathwaysUrsolic acid, a pentacyclin triterpene, potentiates TRAIL-induced apoptosis through p53-independent up-regulation of death receptors: evidence for the role of reactive oxygen species and JNKTriterpenoids as potential agents for the chemoprevention and therapy of breast cancer.Antiproliferative activity of Vallaris glabra Kuntze (Apocynaceae)Targeting orphan nuclear receptors for treatment of metabolic diseases and autoimmunityTargeting apoptosis pathway with natural terpenoids: implications for treatment of breast and prostate cancer.Dietary compounds as potent inhibitors of the signal transducers and activators of transcription (STAT) 3 regulatory network.Identification of SR2211: a potent synthetic RORγ-selective modulator.Ursolic acid induces apoptosis in human leukaemia cells and exhibits anti-leukaemic activity in nude mice through the PKB pathwayA phase I pharmacokinetic study of ursolic acid nanoliposomes in healthy volunteers and patients with advanced solid tumors.Ursolic acid inhibits growth and metastasis of human colorectal cancer in an orthotopic nude mouse model by targeting multiple cell signaling pathways: chemosensitization with capecitabineUrsolic acid inhibits the growth of human pancreatic cancer and enhances the antitumor potential of gemcitabine in an orthotopic mouse model through suppression of the inflammatory microenvironmentEffects of combined phytochemicals on skin tumorigenesis in SENCAR mice.Development and characterisation of ursolic acid nanocrystals without stabiliser having improved dissolution rate and in vitro anticancer activity.Ursolic acid sensitizes radioresistant NSCLC cells expressing HIF-1α through reducing endogenous GSH and inhibiting HIF-1α.Ursolic acid derivative FZU-03,010 inhibits STAT3 and induces cell cycle arrest and apoptosis in renal and breast cancer cells.Ursolic Acid Induces Apoptosis of Prostate Cancer Cells via the PI3K/Akt/mTOR Pathway.Ursolic acid, a potential anticancer compound for breast cancer therapy.Experimental and Clinical Pharmacology of Ziziphus jujuba Mills.Preparation, physicochemical characterization, and cell viability evaluation of long-circulating and pH-sensitive liposomes containing ursolic acid.Antineoplastic agents. 595. Structural modifications of betulin and the X-ray crystal structure of an unusual betulin amine dimer.Oldenlandia diffusa extracts exert antiproliferative and apoptotic effects on human breast cancer cells through ERα/Sp1-mediated p53 activation.Induction of apoptotic cell death by ursolic acid through mitochondrial death pathway and extrinsic death receptor pathway in MDA-MB-231 cells.Ursolic acid inhibits multiple cell survival pathways leading to suppression of growth of prostate cancer xenograft in nude mice.Predictive simulation approach for designing cancer therapeutic regimens with novel biological mechanisms.Organotypic culture of breast tumor explants as a multicellular system for the screening of natural compounds with antineoplastic potential.Ursolic acid promotes cancer cell death by inducing Atg5-dependent autophagy.Degradation of Bcl-2 by XIAP and ARTS Promotes Apoptosis.Synergism of ursolic acid and cisplatin promotes apoptosis and enhances growth inhibition of cervical cancer cells via suppressing NF-κB p65.Juglanin ameliorates UVB‑induced skin carcinogenesis via anti‑inflammatory and proapoptotic effects in vivo and in vitro.Structure-Based Classification and Anti-Cancer Effects of Plant Metabolites
P2860
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P2860
Ursolic acid triggers apoptosis and Bcl-2 downregulation in MCF-7 breast cancer cells.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh
2009年學術文章
@zh-hant
name
Ursolic acid triggers apoptosis and Bcl-2 downregulation in MCF-7 breast cancer cells.
@en
Ursolic acid triggers apoptosis and Bcl-2 downregulation in MCF-7 breast cancer cells.
@nl
type
label
Ursolic acid triggers apoptosis and Bcl-2 downregulation in MCF-7 breast cancer cells.
@en
Ursolic acid triggers apoptosis and Bcl-2 downregulation in MCF-7 breast cancer cells.
@nl
prefLabel
Ursolic acid triggers apoptosis and Bcl-2 downregulation in MCF-7 breast cancer cells.
@en
Ursolic acid triggers apoptosis and Bcl-2 downregulation in MCF-7 breast cancer cells.
@nl
P2093
P2860
P1433
P1476
Ursolic acid triggers apoptosis and Bcl-2 downregulation in MCF-7 breast cancer cells.
@en
P2093
M Spiliotaki
N Aligiannis
P Moutsatsou
T G Sourlingas
Z Papoutsi
P2860
P304
P356
10.1080/07357900802672712
P577
2009-08-01T00:00:00Z