Thiazole antibiotics target FoxM1 and induce apoptosis in human cancer cells. - Wikidata - wikimedia - TriplyDB

Thiazole antibiotics target FoxM1 and induce apoptosis in human cancer cells.

Thiazole antibiotics target FoxM1 and induce apoptosis in human cancer cells.

http://www.wikidata.org/entity/Q39851883

about

Thiopeptide antibiotics: retrospective and recent advances Thiostrepton and derivatives exhibit antimalarial and gametocytocidal activity by dually targeting parasite proteasome and apicoplast FOXM1 in sarcoma: role in cell cycle, pluripotency genes and stem cell pathways RETRACTED: Gene-gene interaction network analysis of ovarian cancer using TCGA data ThioFinder: a web-based tool for the identification of thiopeptide gene clusters in DNA sequences FOXM1 is an oncogenic mediator in Ewing Sarcoma Peroxiredoxin 3 is a redox-dependent target of thiostrepton in malignant mesothelioma cells Deletion of Forkhead Box M1 transcription factor from respiratory epithelial cells inhibits pulmonary tumorigenesis.FoxM1 is a general target for proteasome inhibitors.MiR-370 sensitizes chronic myeloid leukemia K562 cells to homoharringtonine by targeting Forkhead box M1 Identification of neuron selective androgen receptor inhibitors.Forkhead box M1 transcription factor: a novel target for cancer therapy.Thiazole antibiotic thiostrepton synergize with bortezomib to induce apoptosis in cancer cells.Phosphorylation of the HIV-1 capsid by MELK triggers uncoating to promote viral cDNA synthesis.Forkhead box L1 is frequently downregulated in gallbladder cancer and inhibits cell growth through apoptosis induction by mitochondrial dysfunction.New potential anti-cancer agents synergize with bortezomib and ABT-737 against prostate cancer.FoxM1 mediates resistance to herceptin and paclitaxel.Aberrant activation of ERK/FOXM1 signaling cascade triggers the cell migration/invasion in ovarian cancer cells.Production of a new thiopeptide antibiotic, TP-1161, by a marine Nocardiopsis species.Suppression of FOXM1 sensitizes human cancer cells to cell death induced by DNA-damage.Binding induced RNA conformational changes control substrate recognition and catalysis by the thiostrepton resistance methyltransferase (Tsr).FoxM1 is a novel target of a natural agent in pancreatic cancer.Down-regulation of FoxM1 by thiostrepton or small interfering RNA inhibits proliferation, transformation ability and angiogenesis, and induces apoptosis of nasopharyngeal carcinoma cells.Negative regulation of the oncogenic transcription factor FoxM1 by thiazolidinediones and mithramycin.Overexpression of FOXM1 is associated with metastases of nasopharyngeal carcinoma Genome-wide expression analysis of Middle Eastern colorectal cancer reveals FOXM1 as a novel target for cancer therapy Structural basis and dynamics of multidrug recognition in a minimal bacterial multidrug resistance system.Azithromycin synergistically enhances anti-proliferative activity of vincristine in cervical and gastric cancer cells.ROS inhibitor N-acetyl-L-cysteine antagonizes the activity of proteasome inhibitors Sorafenib inhibits proliferation and invasion of human hepatocellular carcinoma cells via up-regulation of p53 and suppressing FoxM1.Heterologous expression of the thiopeptide antibiotic GE2270 from Planobispora rosea ATCC 53733 in Streptomyces coelicolor requires deletion of ribosomal genes from the expression construct.Identification of the thiazolyl peptide GE37468 gene cluster from Streptomyces ATCC 55365 and heterologous expression in Streptomyces lividans.Identification of FOXM1 as a therapeutic target in B-cell lineage acute lymphoblastic leukaemia.Quinoline-based clioquinol and nitroxoline exhibit anticancer activity inducing FoxM1 inhibition in cholangiocarcinoma cells.Micelle-encapsulated thiostrepton as an effective nanomedicine for inhibiting tumor growth and for suppressing FOXM1 in human xenografts.A FOXM1 Dependent Mesenchymal-Epithelial Transition in Retinal Pigment Epithelium Cells.The suppression of FOXM1 and its targets in breast cancer xenograft tumors by siRNA Thiostrepton is an inducer of oxidative and proteotoxic stress that impairs viability of human melanoma cells but not primary melanocytes Nucleophosmin interacts with FOXM1 and modulates the level and localization of FOXM1 in human cancer cells.Investigation of FOXM1 as a Potential New Target for Melanoma.

P2860

Q26852567-F30A8C67-E646-4EBF-8F7D-07083CAF71FC Q27973422-ED6A751B-295E-490D-8085-9A23B99C3189 Q28076296-8277E874-7D8F-4F47-8E05-4B7B40EE97DE Q28386402-89160B76-F12D-4DAA-A562-703326A1A3AD Q28483962-4DBECB05-B9FD-458B-9A56-A61384018C17 Q28485291-EF1ADD69-2976-46AE-AC4E-BFBB81262C93 Q28728015-0AB0428D-CF19-460C-A2C5-7378304818D4 Q33492769-EAD60987-DE12-4C2E-98B4-C6B88D2CFEB1 Q33492774-38B6BE05-BD23-4F2A-A581-B361D7B90674 Q33587320-77B9B26D-76F3-45E9-9FBA-D7FD899B9BBE Q33711488-31222F4B-B83A-4307-B646-3C18D01076A0 Q33729250-6DD22EF9-0D0F-4F94-BE1D-75BD3EEEAF7C Q33834181-CAC2A951-77E5-456D-A2C4-535FF6B441F3 Q33880794-2C56FA50-B4F7-4219-8414-D8CBB5FAC5C9 Q33882630-907DD826-12CD-4350-82A5-6879D146E031 Q33920494-5F7FACEC-3556-4FC6-A596-60BCB196527A Q33946664-8D27A213-060E-4907-9E3B-33AA9E8FF47D Q34000057-CA23CDF4-B50E-4C9D-8E2F-8BA83AE93FFF Q34121673-BACB39CA-E556-4DF5-ADD3-F709853C8B3F Q34185710-8AD275A2-FD09-4B80-83BC-B8E0A4B52999 Q34249082-F7F542D4-9D1C-41BE-A442-D3C9FD9AA386 Q34286063-EC994F05-89C2-4923-8B30-A2B00CA18F00 Q34371119-D95C8A61-3B89-4AAC-BF1C-0897AB3C88A7 Q34420463-0A76EC67-4597-4C60-A553-49C07E832221 Q34589178-0F8E334D-22B3-4036-86CE-46B09230A4CA Q34760700-CAB10F25-255B-42EC-9E35-D4179297A1B9 Q34793047-8D60B746-6718-40F0-95E0-5CDAA33A483D Q35038110-19AEB30F-3221-403C-89AC-5BFB4642E664 Q35065984-E6E82413-42B1-4CE4-BCAB-EE34A68F69E8 Q35080145-D831905C-0401-4FA0-B8EA-9E8D7C5EC3B2 Q35111952-9B266DDC-00A1-4047-A591-E225443212B1 Q35164679-D32B61D2-7831-4B12-95EA-6BD0134B9F4F Q35197045-9192F38D-752B-46FD-BF68-105F056D383C Q35410253-170F9837-F427-4308-9010-6D5E7A406259 Q35613017-A6F8CC44-D300-4272-9C45-03413634FFCC Q35677149-9BE227EE-8B53-4B6C-9568-0CECBF6E1DB2 Q35764362-1007C93B-3D60-499A-B0F6-E30D93065306 Q35823218-BFE88E48-4C7F-4884-988B-5AAC06096AA0 Q35842155-E3410E9C-C781-424A-9924-0214644E1AD4 Q35861978-7D503F1D-6F2B-465F-85BF-99AEF3B46502

P2860

Thiazole antibiotics target FoxM1 and induce apoptosis in human cancer cells.

http://www.wikidata.org/entity/Q39851883

description

2009 nî lūn-bûn

@nan

2009年の論文

@ja

2009年学术文章

@wuu

2009年学术文章

@zh-cn

2009年学术文章

@zh-hans

2009年学术文章

@zh-my

2009年学术文章

@zh-sg

2009年學術文章

@yue

2009年學術文章

@zh

2009年學術文章

@zh-hant

name

Thiazole antibiotics target FoxM1 and induce apoptosis in human cancer cells.

@en

Thiazole antibiotics target FoxM1 and induce apoptosis in human cancer cells.

@nl

type

label

Thiazole antibiotics target FoxM1 and induce apoptosis in human cancer cells.

@en

Thiazole antibiotics target FoxM1 and induce apoptosis in human cancer cells.

@nl

prefLabel

Thiazole antibiotics target FoxM1 and induce apoptosis in human cancer cells.

@en

Thiazole antibiotics target FoxM1 and induce apoptosis in human cancer cells.

@nl

P1433

Q39851883-4D3BFCA5-A19C-48A4-A877-4FC31D8DE93C

P1476

Q39851883-838186A6-801C-428D-87E7-E08A051A4613

P2093

Q39851883-091D9D5B-B126-418E-BE9F-C615738B434F

Q39851883-27AECB7D-1776-47D2-AD27-2D7FDF730C16

Q39851883-4B28FF06-B222-48FA-B512-ADBDEA0B9E44

P2860

Q39851883-02F5A247-778A-4DE9-AFD8-A0EB41EF93EA

Q39851883-08D2FFDA-6E5F-4FAC-AB3B-0AD705D4B5A7

Q39851883-0B15592F-A616-4293-9692-0BFDE8D4267D

Q39851883-0DB5738F-CF77-4F14-96F7-E5B15B1607D8

Q39851883-1701C62F-9BA3-4310-A9E0-851080688AE6

Q39851883-180C1129-54EB-4B4F-BB76-4B8717284CB8

Q39851883-1EA62ACB-4E42-49D9-9775-03608CAF5BF7

Q39851883-20BAE991-4B1D-4664-889C-4802C680CB8C

Q39851883-272BC176-6B48-4B7B-B9A6-9E9F891B2240

Q39851883-2AA0B328-6F2F-4A40-9807-5B36B79ED862

P304

Q39851883-BD7CDEA4-95D4-4F0A-92D2-683B02112F8E

P31

Q39851883-0345BD4A-433B-449E-A987-4DF3FA20BAED

P356

Q39851883-C3D3AB7E-CE29-41EF-8C3D-F93FC432D240

P407

Q39851883-C4A06C38-C625-4350-9784-F62C93C204BC

P433

Q39851883-F6E5ECB5-5303-41AF-A78B-67E68FC95071

P478

Q39851883-36F7D22C-8A3E-4FB0-B971-3BBCCDFCB696

P577

Q39851883-8EA92F2D-33A6-4755-81C4-3E0CF1584873

P5875

Q39851883-F2C49E6C-2718-437E-A803-4DAE8984CDEF

P698

Q39851883-CC7B763C-D457-42EA-91E5-9030E81FD0CA

P921

Q39851883-305F2AB9-946D-45EF-A024-12D53914B77C

Q39851883-93412B9E-91F6-4B98-9D63-AAEEB6ECF52E

P932

Q39851883-F8F3A7F4-22CF-45DA-B514-9ECEB720D826

P356

JOURNAL.PONE.0005592

P1433

P1476

Thiazole antibiotics target FoxM1 and induce apoptosis in human cancer cells.

@en

P2093

Andrei L Gartel

http://www.w3.org/2001/XMLSchema#string

Marianna Halasi

http://www.w3.org/2001/XMLSchema#string

Uppoor G Bhat

http://www.w3.org/2001/XMLSchema#string

P2860

Hepatocyte nuclear factor 3/fork head homolog 11 is expressed in proliferating epithelial and mesenchymal cells of embryonic and adult tissues

Increased levels of the FoxM1 transcription factor accelerate development and progression of prostate carcinomas in both TRAMP and LADY transgenic mice

Foxm1b transcription factor is essential for development of hepatocellular carcinomas and is negatively regulated by the p19ARF tumor suppressor

Structural basis for contrasting activities of ribosome binding thiazole antibiotics

FOXM1 is a downstream target of Gli1 in basal cell carcinomas

Down-regulation of Forkhead Box M1 transcription factor leads to the inhibition of invasion and angiogenesis of pancreatic cancer cells

The emerging roles of forkhead box (Fox) proteins in cancer

Loss of the forkhead transcription factor FoxM1 causes centrosome amplification and mitotic catastrophe

FOXM1, a typical proliferation-associated transcription factor

The Forkhead Box m1 transcription factor stimulates the proliferation of tumor cells during development of lung cancer

P304

e5592

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1371/JOURNAL.PONE.0005592

http://www.w3.org/2001/XMLSchema#string

P407

P433

5

http://www.w3.org/2001/XMLSchema#string

P478

4

http://www.w3.org/2001/XMLSchema#string

P577

2009-05-18T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

24425524

http://www.w3.org/2001/XMLSchema#string

P698

19440351

http://www.w3.org/2001/XMLSchema#string

P921

apoptotic process

P932

2680058

http://www.w3.org/2001/XMLSchema#string