The natural marine anhydrophytosphingosine, Jaspine B, induces apoptosis in melanoma cells by interfering with ceramide metabolism.
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Ceramide as a Target of Marine Triterpene Glycosides for Treatment of Human Myeloid LeukemiaSynthesis and biological evaluation of carbocyclic analogues of pachastrissamine.Recently confirmed apoptosis-inducing lead compounds isolated from marine sponge of potential relevance in cancer treatment.Antitumor effect of a polypeptide fraction from Arca subcrenata in vitro and in vivoThe Cytotoxicity of Dacarbazine Potentiated by Sea Cucumber Saponin in Resistant B16F10 Melanoma Cells through Apoptosis Induction.Finding chemo: the search for marine-based pharmaceutical drugs active against cancer.Jaspine B induces nonapoptotic cell death in gastric cancer cells independently of its inhibition of ceramide synthase.Antitumour effects of tetrazanbigen against human hepatocellular carcinoma QGY-7701 through inducing lipid accumulation in vitro and in vivo.A novel jaspine B-ceramide hybrid modulates sphingolipid metabolism.Therapeutic Strategies and Pharmacological Tools Influencing S1P Signaling and Metabolism.Pachastrissamine from Pachastrissa sp. inhibits melanoma cell growth by dual inhibition of Cdk2 and ERK-mediated FOXO3 downregulation.Syntheses of sulfur and selenium analogues of pachastrissamine via double displacements of cyclic sulfate.Design and synthesis of pyrrolidine-containing sphingomimetics.Pharmacokinetics of Jaspine B and Enhancement of Intestinal Absorption of Jaspine B in the Presence of Bile Acid in Rats.Ceramide in cystic fibrosis: a potential new target for therapeutic intervention.Stereodivergent synthesis of jaspine B and its isomers using a carbohydrate-derived alkoxyallene as C3-building blockMarine Sponge Natural Products with Anticancer Potential: An Updated Review.Formation of tetrahydrofurans via a 5-endo-tet cyclization of aziridines--synthesis of (-)-pachastrissamine.Identification of novel CERT ligands as potential ceramide trafficking inhibitors.Heteronemin, a Marine Sesterterpenoid-Type Metabolite, Induces Apoptosis in Prostate LNcap Cells via Oxidative and ER Stress Combined with the Inhibition of Topoisomerase II and Hsp90.
P2860
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P2860
The natural marine anhydrophytosphingosine, Jaspine B, induces apoptosis in melanoma cells by interfering with ceramide metabolism.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh
2009年學術文章
@zh-hant
name
The natural marine anhydrophyt ...... ring with ceramide metabolism.
@en
The natural marine anhydrophyt ...... ring with ceramide metabolism.
@nl
type
label
The natural marine anhydrophyt ...... ring with ceramide metabolism.
@en
The natural marine anhydrophyt ...... ring with ceramide metabolism.
@nl
prefLabel
The natural marine anhydrophyt ...... ring with ceramide metabolism.
@en
The natural marine anhydrophyt ...... ring with ceramide metabolism.
@nl
P2093
P50
P1476
The natural marine anhydrophyt ...... ring with ceramide metabolism.
@en
P2093
Marie-José Bonnafé
Stéphane Carpentier
Thierry Levade
Yahya Salma
Yves Génisson
P304
P356
10.1016/J.BCP.2009.05.002
P407
P577
2009-05-09T00:00:00Z