Biochemical and analytical development of the CIME cocktail for drug fate assessment in humans.
about
Susceptibility of juvenile and adult blood-brain barrier to endothelin-1: regulation of P-glycoprotein and breast cancer resistance protein expression and transport activityThe effects of obesity on drug pharmacokinetics in humans.Design optimisation for pharmacokinetic modeling of a cocktail of phenotyping drugs.A limited sampling strategy based on maximum a posteriori Bayesian estimation for a five-probe phenotyping cocktail.Safety and pharmacokinetics of the CIME combination of drugs and their metabolites after a single oral dosing in healthy volunteers.Buspirone, fexofenadine, and omeprazole: quantification of probe drugs and their metabolites in human plasma.Evaluation of CYP2C9 Activity in Rats: Use of Tolbutamide Alone and in Combined with Bupropion.Evaluation of seven drug metabolisms and clearances by cryopreserved human primary hepatocytes cultivated in microfluidic biochips.Simultaneous LC-MS/MS quantification of P-glycoprotein and cytochrome P450 probe substrates and their metabolites in DBS and plasma.Can a cocktail designed for phenotyping pharmacokinetics and metabolism enzymes in human be used efficiently in rat?
P2860
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P2860
Biochemical and analytical development of the CIME cocktail for drug fate assessment in humans.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
2010年學術文章
@zh
2010年學術文章
@zh-hant
name
Biochemical and analytical dev ...... rug fate assessment in humans.
@en
Biochemical and analytical dev ...... rug fate assessment in humans.
@nl
type
label
Biochemical and analytical dev ...... rug fate assessment in humans.
@en
Biochemical and analytical dev ...... rug fate assessment in humans.
@nl
prefLabel
Biochemical and analytical dev ...... rug fate assessment in humans.
@en
Biochemical and analytical dev ...... rug fate assessment in humans.
@nl
P2093
P50
P356
P1476
Biochemical and analytical dev ...... drug fate assessment in humans
@en
P2093
Henri Bénech
Laurent Becquemont
Marcel Delaforge
Mikael Levi
Orianne Videau
P304
P356
10.1002/RCM.4641
P577
2010-08-01T00:00:00Z