Structural basis for ligand-dependent dimerization of phenylalanine hydroxylase regulatory domain.
about
From structural biology to designing therapy for inborn errors of metabolismX-ray Scattering Studies of Protein Structural Dynamics.Substituting Tyr138 in the active site loop of human phenylalanine hydroxylase affects catalysis and substrate activation.Stable preparations of tyrosine hydroxylase provide the solution structure of the full-length enzyme.Stabilization of tryptophan hydroxylase 2 by l-phenylalanine-induced dimerization.PKU mutation p.G46S prevents the stereospecific binding of l-phenylalanine to the dimer of human phenylalanine hydroxylase regulatory domain.The regulatory domain of human tryptophan hydroxylase 1 forms a stable dimerMulticlinic Observations on the Simplified Diet in PKUDiscovering Selective Diguanylate Cyclase Inhibitors: From PleD to Discrimination of the Active Site of Cyclic-di-GMP Phosphodiesterases.Structure and characterization of a class 3B proline utilization A: Ligand-induced dimerization and importance of the C-terminal domain for catalysis.Structural basis for the regulation of human 5,10-methylenetetrahydrofolate reductase by phosphorylation and S-adenosylmethionine inhibition.
P2860
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P2860
Structural basis for ligand-dependent dimerization of phenylalanine hydroxylase regulatory domain.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
Structural basis for ligand-de ...... hydroxylase regulatory domain.
@en
Structural basis for ligand-de ...... hydroxylase regulatory domain.
@nl
type
label
Structural basis for ligand-de ...... hydroxylase regulatory domain.
@en
Structural basis for ligand-de ...... hydroxylase regulatory domain.
@nl
prefLabel
Structural basis for ligand-de ...... hydroxylase regulatory domain.
@en
Structural basis for ligand-de ...... hydroxylase regulatory domain.
@nl
P2093
P2860
P356
P1433
P1476
Structural basis for ligand-de ...... hydroxylase regulatory domain.
@en
P2093
Dipali Patel
Fiona Fitzpatrick
Jolanta Kopec
Thomas J McCorvie
Wyatt W Yue
P2860
P2888
P356
10.1038/SREP23748
P407
P577
2016-04-06T00:00:00Z