Astrocytic protection of spinal motor neurons but not cortical neurons against loss of Als2/alsin function.
about
Loss of ALS2/Alsin exacerbates motor dysfunction in a SOD1-expressing mouse ALS model by disturbing endolysosomal traffickingCytoplasmic mislocalization of TDP-43 is toxic to neurons and enhanced by a mutation associated with familial amyotrophic lateral sclerosis.Cryptic amyloidogenic elements in mutant NEFH causing Charcot-Marie-Tooth 2 trigger aggresome formation and neuronal death.Autophagy induction enhances TDP43 turnover and survival in neuronal ALS models.Genetic heterogeneity of amyotrophic lateral sclerosis: implications for clinical practice and research.FUS/TLS-immunoreactive neuronal and glial cell inclusions increase with disease duration in familial amyotrophic lateral sclerosis with an R521C FUS/TLS mutation.Autophagic processes increase during senescence in cultured sheep neurons and astrocytes.
P2860
Q27332255-B0DC837A-826D-483B-A9AC-71F904EBAF6DQ33649745-3DB5CB12-D30A-45AF-B27C-830B5217D1F1Q33909546-2030AF47-78DE-4566-A849-9245E0D609AEQ33930825-1BAD075F-1BE4-4A3A-A67E-01561FC1A1DEQ34401653-F1F72C45-BD22-467A-A1F4-D912888FE2DEQ48414675-C2FE5D7F-AC1A-4321-A431-78F4037C1242Q55478732-B9448A21-EA3B-425C-B32B-907D4D254DF5
P2860
Astrocytic protection of spinal motor neurons but not cortical neurons against loss of Als2/alsin function.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
2009年论文
@zh
2009年论文
@zh-cn
name
Astrocytic protection of spina ...... t loss of Als2/alsin function.
@en
Astrocytic protection of spina ...... t loss of Als2/alsin function.
@nl
type
label
Astrocytic protection of spina ...... t loss of Als2/alsin function.
@en
Astrocytic protection of spina ...... t loss of Als2/alsin function.
@nl
prefLabel
Astrocytic protection of spina ...... t loss of Als2/alsin function.
@en
Astrocytic protection of spina ...... t loss of Als2/alsin function.
@nl
P2093
P356
P1476
Astrocytic protection of spina ...... st loss of Als2/alsin function
@en
P2093
P304
P356
10.1093/HMG/DDP136
P577
2009-03-20T00:00:00Z