Small interfering RNA targeting the subunit ATP6L of proton pump V-ATPase overcomes chemoresistance of breast cancer cells.
about
TM9SF4 is a novel V-ATPase-interacting protein that modulates tumor pH alterations associated with drug resistance and invasiveness of colon cancer cellsInhibition of iron uptake is responsible for differential sensitivity to V-ATPase inhibitors in several cancer cell lines.Trafficking microenvironmental pHs of polycationic gene vectors in drug-sensitive and multidrug-resistant MCF7 breast cancer cells.pH-responsive polymeric sirna carriers sensitize multidrug resistant ovarian cancer cells to doxorubicin via knockdown of polo-like kinase 1.Microenvironmental acidosis in carcinogenesis and metastases: new strategies in prevention and therapy.Nanocarrier mediated delivery of siRNA/miRNA in combination with chemotherapeutic agents for cancer therapy: current progress and advances.ATP6V0C knockdown in neuroblastoma cells alters autophagy-lysosome pathway function and metabolism of proteins that accumulate in neurodegenerative disease.Impairment of lysosomal activity as a therapeutic modality targeting cancer stem cells of embryonal rhabdomyosarcoma cell line RD.pH-Responsive therapeutic solid lipid nanoparticles for reducing P-glycoprotein-mediated drug efflux of multidrug resistant cancer cells.Intermittent high dose proton pump inhibitor enhances the antitumor effects of chemotherapy in metastatic breast cancerEnoxacin directly inhibits osteoclastogenesis without inducing apoptosisIdentification of V-ATPase as a molecular sensor of SOX11-levels and potential therapeutic target for mantle cell lymphoma.Rational identification of enoxacin as a novel V-ATPase-directed osteoclast inhibitor.Evidence-based support for the use of proton pump inhibitors in cancer therapyInhibitors of vacuolar ATPase proton pumps inhibit human prostate cancer cell invasion and prostate-specific antigen expression and secretion.Breast cancer associated a2 isoform vacuolar ATPase immunomodulates neutrophils: potential role in tumor progressionThe Function of V-ATPases in CancerRegulation and roles of bicarbonate transporters in cancer.Proton pump inhibitors as anti vacuolar-ATPases drugs: a novel anticancer strategy.Acid-base transport in pancreatic cancer: molecular mechanisms and clinical potential.Acridine Orange/exosomes increase the delivery and the effectiveness of Acridine Orange in human melanoma cells: A new prototype for theranostics of tumors.Lansoprazole and carbonic anhydrase IX inhibitors sinergize against human melanoma cells.Extracellular and Luminal pH Regulation by Vacuolar H+-ATPase Isoform Expression and Targeting to the Plasma Membrane and Endosomes.The Role of pH Regulation in Cancer Progression.Proton pump inhibitors (PPIs) impact on tumour cell survival, metastatic potential and chemotherapy resistance, and affect expression of resistance-relevant miRNAs in esophageal cancer.Tumor-associated vacuolar ATPase subunit promotes tumorigenic characteristics in macrophages.LASS2 enhances chemosensitivity of breast cancer by counteracting acidic tumor microenvironment through inhibiting activity of V-ATPase proton pump.The renal v-ATPase a4 subunit is expressed in specific subtypes of human gliomas.Vacuolar H+ -ATPase c protects glial cell death induced by sodium nitroprusside under glutathione-depleted condition.pH-dependent antitumor activity of proton pump inhibitors against human melanoma is mediated by inhibition of tumor acidity.F-actin reorganization by V-ATPase inhibition in prostate cancer.Repositioning of proton pump inhibitors in cancer therapy.V-ATPase-dependent repression of androgen receptor in prostate cancer cells.pH-Responsive Cross-Linked Low Molecular Weight Polyethylenimine as an Efficient Gene Vector for Delivery of Plasmid DNA Encoding Anti-VEGF-shRNA for Tumor TreatmentVacuolar H+-ATPase: An Essential Multitasking Enzyme in Physiology and Pathophysiology
P2860
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P2860
Small interfering RNA targeting the subunit ATP6L of proton pump V-ATPase overcomes chemoresistance of breast cancer cells.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
2009年论文
@zh
2009年论文
@zh-cn
name
Small interfering RNA targetin ...... stance of breast cancer cells.
@en
Small interfering RNA targetin ...... stance of breast cancer cells.
@nl
type
label
Small interfering RNA targetin ...... stance of breast cancer cells.
@en
Small interfering RNA targetin ...... stance of breast cancer cells.
@nl
prefLabel
Small interfering RNA targetin ...... stance of breast cancer cells.
@en
Small interfering RNA targetin ...... stance of breast cancer cells.
@nl
P2093
P1433
P1476
Small interfering RNA targetin ...... stance of breast cancer cells.
@en
P2093
Angelo De Milito
Francesco Lozupone
Haiyan You
Huiqun Shu
Jianren Gu
Stefano Fais
P304
P356
10.1016/J.CANLET.2009.02.023
P407
P577
2009-03-18T00:00:00Z