about
Trib1 is a lipid- and myocardial infarction-associated gene that regulates hepatic lipogenesis and VLDL production in miceTargeting adipose tissue via systemic gene therapyDevelopment and rescue of human familial hypercholesterolaemia in a xenograft mouse modelCa2+ Binding/Permeation via Calcium Channel, CaV1.1, Regulates the Intracellular Distribution of the Fatty Acid Transport Protein, CD36, and Fatty Acid MetabolismDeletion of murine Arv1 results in a lean phenotype with increased energy expenditure.Lipidomic analyses of female mice lacking hepatic lipase and endothelial lipase indicate selective modulation of plasma lipid species.Adeno-associated virus serotype 8 gene therapy leads to significant lowering of plasma cholesterol levels in humanized mouse models of homozygous and heterozygous familial hypercholesterolemia.Streptococcal serum opacity factor promotes cholesterol ester metabolism and bile acid secretion in vitro and in vivo.Genetic manipulation of the ApoF/Stat2 locus supports an important role for type I interferon signaling in atherosclerosis.Thyroid hormone enhances the ability of serum to accept cellular cholesterol via the ABCA1 transporter.Technological advances in the study of HLA-DRA promoter regulation: extending the functions of CIITA, Oct-1, Rb, and RFX.Overexpression of apolipoprotein F reduces HDL cholesterol levels in vivo.Identification of insulin-responsive regions in the HMG-CoA reductase promoter.Adeno-associated viruses as liver-directed gene delivery vehicles: focus on lipoprotein metabolism.Diabetes alters the occupancy of the hepatic 3-hydroxy-3-methylglutaryl-CoA reductase promoter.Phospholipidation of HDL--how much is too much?Overexpression of apolipoprotein O does not impact on plasma HDL levels or functionality in human apolipoprotein A-I transgenic mice
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description
hulumtues
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
William R Lagor
@nl
William R Lagor
@sl
William R. Lagor
@en
William R. Lagor
@es
type
label
William R Lagor
@nl
William R Lagor
@sl
William R. Lagor
@en
William R. Lagor
@es
prefLabel
William R Lagor
@nl
William R Lagor
@sl
William R. Lagor
@en
William R. Lagor
@es
P106
P1153
9237315700
P21
P31
P496
0000-0002-1703-5125