Selection of an avian retrovirus mutant with extended receptor usage

Selection of an avian retrovirus mutant with extended receptor usage

Item
http://www.wikidata.org/entity/Q39881539
Genome structure and expression of the ev/J family of avian endogenous viruses.Independent isolates of the emerging subgroup J avian leukosis virus derive from a common ancestor.Identification of key residues in subgroup A avian leukosis virus envelope determining receptor binding affinity and infectivity of cells expressing chicken or quail Tva receptor.The receptor for the subgroup C avian sarcoma and leukosis viruses, Tvc, is related to mammalian butyrophilins, members of the immunoglobulin superfamily.Two different molecular defects in the Tva receptor gene explain the resistance of two tvar lines of chickens to infection by subgroup A avian sarcoma and leukosis viruses.Variable pleiotropic effects from mutations at the same locus hamper prediction of fitness from a fitness componentMechanisms of avian retroviral host range extension.Intronic deletions that disrupt mRNA splicing of the tva receptor gene result in decreased susceptibility to infection by avian sarcoma and leukosis virus subgroup A.The unique envelope gene of the subgroup J avian leukosis virus derives from ev/J proviruses, a novel family of avian endogenous viruses.Extended analysis of the in vitro tropism of porcine endogenous retrovirus.Evolutionary pressure of a receptor competitor selects different subgroup a avian leukosis virus escape variants with altered receptor interactions.Retroviral host range extension is coupled with Env-activating mutations resulting in receptor-independent entry.The hr1 and fusion peptide regions of the subgroup B avian sarcoma and leukosis virus envelope glycoprotein influence low pH-dependent membrane fusion.Evolution of broad host range in retroviruses leads to cell death mediated by highly cytopathic variants.
P2860

Selection of an avian retrovirus mutant with extended receptor usage

Item
http://www.wikidata.org/entity/Q39881539
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
1997年學術文章
@zh
1997年學術文章
@zh-hant
name
Selection of an avian retrovirus mutant with extended receptor usage
@en
Selection of an avian retrovirus mutant with extended receptor usage.
@nl
type
label
Selection of an avian retrovirus mutant with extended receptor usage
@en
Selection of an avian retrovirus mutant with extended receptor usage.
@nl
prefLabel
Selection of an avian retrovirus mutant with extended receptor usage
@en
Selection of an avian retrovirus mutant with extended receptor usage.
@nl
P1433
P1476
P2093
P2860
P304
P31
P407
P433
P478
P577
P698
P932
P1433
P1476
Selection of an avian retrovirus mutant with extended receptor usage
@en
P2093
P2860
P304
P31
P407
P433
P478
P577
P698
P932