The up-regulation of BACE1 mediated by hypoxia and ischemic injury: role of oxidative stress and HIF1alpha.
about
Signaling effect of amyloid-beta(42) on the processing of AbetaPPAmyloid-beta Alzheimer targets - protein processing, lipid rafts, and amyloid-beta poresCerebrovascular disease in ageing and Alzheimer's diseaseImproved mitochondrial function in brain aging and Alzheimer disease - the new mechanism of action of the old metabolic enhancer piracetamPathophysiology of the neurovascular unit: disease cause or consequence?Monoaminergic and Histaminergic Strategies and Treatments in Brain DiseasesHypoxia due to cardiac arrest induces a time-dependent increase in serum amyloid β levels in humansNeurovascular pathways to neurodegeneration in Alzheimer's disease and other disordersBridging Type 2 Diabetes and Alzheimer's Disease: Assembling the Puzzle Pieces in the Quest for the Molecules With Therapeutic and Preventive PotentialDose-specific effect of simvastatin on hypoxia-induced HIF-1α and BACE expression in Alzheimer's disease cybrid cells.Hypersensitivity of the hippocampal CA3 region to stress-induced neurodegeneration and amyloidogenesis in a rat model of surgical menopause.Mitochondrial superoxide contributes to blood flow and axonal transport deficits in the Tg2576 mouse model of Alzheimer's disease.Increased iron and free radical generation in preclinical Alzheimer disease and mild cognitive impairment.Hypoxic-ischemic encephalopathy in the term infant.RAGE inhibition in microglia prevents ischemia-dependent synaptic dysfunction in an amyloid-enriched environmentThe metabolic enhancer piracetam ameliorates the impairment of mitochondrial function and neurite outgrowth induced by beta-amyloid peptideAn overview of APP processing enzymes and products.Vascular and metabolic dysfunction in Alzheimer's disease: a review.Leptin counteracts the hypoxia-induced inhibition of spontaneously firing hippocampal neurons: a microelectrode array study.New therapeutic approaches for Alzheimer's disease and cerebral amyloid angiopathy.Melatonin and its agonist ramelteon in Alzheimer's disease: possible therapeutic value.Two novel DNA motifs are essential for BACE1 gene transcriptionAPP as a Protective Factor in Acute Neuronal Insults.Mild oxidative stress induces redistribution of BACE1 in non-apoptotic conditions and promotes the amyloidogenic processing of Alzheimer's disease amyloid precursor proteinDifferential regulation of BACE1 expression by oxidative and nitrosative signalsThe potential dual effects of anesthetic isoflurane on hypoxia-induced caspase-3 activation and increases in β-site amyloid precursor protein-cleaving enzyme levels.Aging and amyloid beta-induced oxidative DNA damage and mitochondrial dysfunction in Alzheimer's disease: implications for early intervention and therapeutics.Differential roles of Aβ processing in hypoxia-induced axonal damage2-Deoxy-D-glucose attenuates isoflurane-induced cytotoxicity in an in vitro cell culture model of H4 human neuroglioma cellsStructural and mechanistic commonalities of amyloid-β and the prion proteinNeuronal and vascular oxidative stress in Alzheimer's disease.Synaptic protein levels altered in vascular dementiaMitochondrion-derived reactive oxygen species lead to enhanced amyloid beta formation.An ECSIT-centric view of Alzheimer's disease.Mitochondria-targeted catalase reduces abnormal APP processing, amyloid β production and BACE1 in a mouse model of Alzheimer's disease: implications for neuroprotection and lifespan extension.Serum amyloid-beta levels are increased in patients with obstructive sleep apnea syndromeBACE1 activity impairs neuronal glucose oxidation: rescue by beta-hydroxybutyrate and lipoic acid.Acute and Chronic Sustained Hypoxia Do Not Substantially Regulate Amyloid-β Peptide Generation In VivoBACE1 is at the crossroad of a toxic vicious cycle involving cellular stress and β-amyloid production in Alzheimer's diseaseExploring the contribution of estrogen to amyloid-Beta regulation: a novel multifactorial computational modeling approach.
P2860
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P2860
The up-regulation of BACE1 mediated by hypoxia and ischemic injury: role of oxidative stress and HIF1alpha.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh
2009年學術文章
@zh-hant
name
The up-regulation of BACE1 med ...... xidative stress and HIF1alpha.
@en
The up-regulation of BACE1 med ...... xidative stress and HIF1alpha.
@nl
type
label
The up-regulation of BACE1 med ...... xidative stress and HIF1alpha.
@en
The up-regulation of BACE1 med ...... xidative stress and HIF1alpha.
@nl
prefLabel
The up-regulation of BACE1 med ...... xidative stress and HIF1alpha.
@en
The up-regulation of BACE1 med ...... xidative stress and HIF1alpha.
@nl
P2093
P50
P1476
The up-regulation of BACE1 med ...... xidative stress and HIF1alpha.
@en
P2093
Elena Tamagno
Erica Novo
Luca Giliberto
Manuela Aragno
Massimo Tabaton
Michela Guglielmotto
Oliviero Danni
Sebastiano Colombatto
P304
P356
10.1111/J.1471-4159.2008.05858.X
P407
P577
2009-02-01T00:00:00Z