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Inference of the Distribution of Selection Coefficients for New Nonsynonymous Mutations Using Large Samples.A Model of Compound Heterozygous, Loss-of-Function Alleles Is Broadly Consistent with Observations from Complex-Disease GWAS Datasets.Estimating the selective effects of heterozygous protein-truncating variants from human exome data.A Temporal Perspective on the Interplay of Demography and Selection on Deleterious Variation in Humans.Genetic Diversity and the Efficacy of Purifying Selection across Plant and Animal Species.The impact of recent population history on the deleterious mutation load in humans and close evolutionary relatives.The Effect of an Extreme and Prolonged Population Bottleneck on Patterns of Deleterious Variation: Insights from the Greenlandic Inuit.Demography and mating system shape the genome-wide impact of purifying selection in Arabis alpina.
P2860
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P2860
description
2016 nî lūn-bûn
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2016年の論文
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2016年学术文章
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2016年学术文章
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2016年学术文章
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2016年学术文章
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2016年学术文章
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2016年學術文章
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2016年學術文章
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2016年學術文章
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When Is Selection Effective?
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When Is Selection Effective?
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type
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When Is Selection Effective?
@en
When Is Selection Effective?
@nl
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When Is Selection Effective?
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When Is Selection Effective?
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P2860
P1433
P1476
When Is Selection Effective?
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P2093
Simon Gravel
P2860
P304
P356
10.1534/GENETICS.115.184630
P407
P50
P577
2016-03-23T00:00:00Z