Transcriptional regulation of chitin synthases by calcineurin controls paradoxical growth of Aspergillus fumigatus in response to caspofungin
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Calcineurin Orchestrates Hyphal Growth, Septation, Drug Resistance and Pathogenesis of Aspergillus fumigatus: Where Do We Go from Here?Calcineurin-Crz1 signaling in lower eukaryotesPhosphorylation of Calcineurin at a novel serine-proline rich region orchestrates hyphal growth and virulence in Aspergillus fumigatusModulation of Alternaria infectoria cell wall chitin and glucan synthesis by cell wall synthase inhibitors.Aspergillus fumigatus Trehalose-Regulatory Subunit Homolog Moonlights To Mediate Cell Wall Homeostasis through Modulation of Chitin Synthase Activity.Chitin synthesis and fungal pathogenesis.Regulatory circuitry governing fungal development, drug resistance, and disease.Differential Aspergillus lentulus echinocandin susceptibilities are Fksp independent.Calcineurin as a Multifunctional Regulator: Unraveling Novel Functions in Fungal Stress Responses, Hyphal Growth, Drug Resistance, and PathogenesisNewer combination antifungal therapies for invasive aspergillosis.Antifungal pharmacokinetics and pharmacodynamicsCalcium-Mediated Induction of Paradoxical Growth following Caspofungin Treatment Is Associated with Calcineurin Activation and Phosphorylation in Aspergillus fumigatus.Hsp70 and the Cochaperone StiA (Hop) Orchestrate Hsp90-Mediated Caspofungin Tolerance in Aspergillus fumigatus.Protein kinase A and fungal virulence: a sinister side to a conserved nutrient sensing pathway.Role of innate immune receptors in paradoxical caspofungin activity in vivo in preclinical aspergillosis.Characterization of calcineurin from Cryptococcus humicola and the application of calcineurin in aluminum tolerance.In vitro activity of calcineurin and heat shock protein 90 Inhibitors against Aspergillus fumigatus azole- and echinocandin-resistant strains.Activation of Melanin Synthesis in Alternaria infectoria by Antifungal DrugsTranscriptional activation of heat shock protein 90 mediated via a proximal promoter region as trigger of caspofungin resistance in Aspergillus fumigatusRegulation of expression, activity and localization of fungal chitin synthases.Echinocandins: are they all the same?Echinocandins: production and applications.The Eagle-like effect of echinocandins: what's in a name?High-dose caspofungin as a component of combination antifungal therapy in 91 patients with neoplastic diseases and hematopoietic stem cell transplantation: a critical review of short-term and long-term adverse events.The importance of connections between the cell wall integrity pathway and the unfolded protein response in filamentous fungi.Heat shock protein 90 (Hsp90): A novel antifungal target against Aspergillus fumigatus.Transcriptomic and molecular genetic analysis of the cell wall salvage response of Aspergillus niger to the absence of galactofuranose synthesis.The Aspergillus fumigatus cell wall integrity signaling pathway: drug target, compensatory pathways, and virulenceCaspofungin: Pharmacodynamics, pharmacokinetics, clinical uses and treatment outcomes.Caspofungin Increases Fungal Chitin and Eosinophil and γδ T Cell-Dependent Pathology in Invasive Aspergillosis.The contribution of Aspergillus fumigatus stress responses to virulence and antifungal resistance.'Strengthening the fungal cell wall through chitin-glucan cross-links: effects on morphogenesis and cell integrity'.Calcineurin in fungal virulence and drug resistance: Prospects for harnessing targeted inhibition of calcineurin for an antifungal therapeutic approach.Manuscript title: antifungal proteins from moulds: analytical tools and potential application to dry-ripened foods.Potential Microbiological Effects of Higher Dosing of Echinocandins.Localization and activity of the calcineurin catalytic and regulatory subunit complex at the septum is essential for hyphal elongation and proper septation in Aspergillus fumigatus.Nano-LC-Q-TOF Analysis of Proteome Revealed Germination of Aspergillus flavus Conidia is Accompanied by MAPK Signalling and Cell Wall Modulation.Echinocandins in antifungal pharmacotherapy.Caspofungin-Mediated Growth Inhibition and Paradoxical Growth in Aspergillus fumigatus involve Fungicidal Hyphal Tip Lysis Coupled with Regenerative Intrahyphal Growth and Dynamic Changes in β-1,3-Glucan Synthase Localization.The Aspergillus fumigatus CrzA Transcription Factor Activates Chitin Synthase Gene Expression during the Caspofungin Paradoxical Effect.
P2860
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P2860
Transcriptional regulation of chitin synthases by calcineurin controls paradoxical growth of Aspergillus fumigatus in response to caspofungin
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2010 nî lūn-bûn
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2010年の論文
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2010年学术文章
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2010年学术文章
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2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
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2010年學術文章
@zh-hant
name
Transcriptional regulation of ...... tus in response to caspofungin
@en
Transcriptional regulation of ...... us in response to caspofungin.
@nl
type
label
Transcriptional regulation of ...... tus in response to caspofungin
@en
Transcriptional regulation of ...... us in response to caspofungin.
@nl
prefLabel
Transcriptional regulation of ...... tus in response to caspofungin
@en
Transcriptional regulation of ...... us in response to caspofungin.
@nl
P2093
P2860
P921
P356
P1476
Transcriptional regulation of ...... tus in response to caspofungin
@en
P2093
B Zachary Perfect
Jarrod R Fortwendel
Luise E Rogg
Praveen R Juvvadi
William J Steinbach
P2860
P304
P356
10.1128/AAC.00854-09
P407
P577
2010-02-01T00:00:00Z