Estrogen and hypoxia regulate estrogen receptor alpha in a synergistic manner.

Estrogen and hypoxia regulate estrogen receptor alpha in a synergistic manner.

Item
http://www.wikidata.org/entity/Q39904883
The cholesterol metabolite 25-hydroxycholesterol activates estrogen receptor α-mediated signaling in cancer cells and in cardiomyocytesThe histone demethylase JMJD2B is regulated by estrogen receptor alpha and hypoxia, and is a key mediator of estrogen induced growth.The G protein-coupled receptor 30 is up-regulated by hypoxia-inducible factor-1alpha (HIF-1alpha) in breast cancer cells and cardiomyocytesThe histone demethylase enzyme KDM3A is a key estrogen receptor regulator in breast cancer.Estrogen receptor beta inhibits transcriptional activity of hypoxia inducible factor-1 through the downregulation of arylhydrocarbon receptor nuclear translocator.Adipocyte hypoxia promotes epithelial-mesenchymal transition-related gene expression and estrogen receptor-negative phenotype in breast cancer cells.Genome-independent hypoxic repression of estrogen receptor alpha in breast cancer cells.Distinct breast cancer stem/progenitor cell populations require either HIF1α or loss of PHD3 to expand under hypoxic conditionsBreast tumor and stromal cell responses to TGF-β and hypoxia in matrix deposition.Estrogen-dependent downregulation of hypoxia-inducible factor (HIF)-2α in invasive breast cancer cellsBRCA1 tumours correlate with a HIF-1alpha phenotype and have a poor prognosis through modulation of hydroxylase enzyme profile expression.
P2860

Estrogen and hypoxia regulate estrogen receptor alpha in a synergistic manner.

Item
http://www.wikidata.org/entity/Q39904883
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
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2008年學術文章
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name
Estrogen and hypoxia regulate estrogen receptor alpha in a synergistic manner.
@en
Estrogen and hypoxia regulate estrogen receptor alpha in a synergistic manner.
@nl
type
label
Estrogen and hypoxia regulate estrogen receptor alpha in a synergistic manner.
@en
Estrogen and hypoxia regulate estrogen receptor alpha in a synergistic manner.
@nl
prefLabel
Estrogen and hypoxia regulate estrogen receptor alpha in a synergistic manner.
@en
Estrogen and hypoxia regulate estrogen receptor alpha in a synergistic manner.
@nl
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Estrogen and hypoxia regulate estrogen receptor alpha in a synergistic manner.
@en
P2093
P304
P31
P356
10.1016/J.BBRC.2008.11.142
P433
P478
P577
P698
P921