Human fetal hemoglobin expression is regulated by the developmental stage-specific repressor BCL11A. - Wikidata - wikimedia - TriplyDB

Human fetal hemoglobin expression is regulated by the developmental stage-specific repressor BCL11A.

Human fetal hemoglobin expression is regulated by the developmental stage-specific repressor BCL11A.

http://www.wikidata.org/entity/Q39908659

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Hydroxyurea for reducing blood transfusion in non-transfusion dependent beta thalassaemias Systematic documentation and analysis of human genetic variation in hemoglobinopathies using the microattribution approach Haploinsufficiency for the erythroid transcription factor KLF1 causes hereditary persistence of fetal hemoglobin Developmental silencing of human zeta-globin gene expression is mediated by the transcriptional repressor RREB1 Compound heterozygosity for KLF1 mutations is associated with microcytic hypochromic anemia and increased fetal hemoglobin Mechanism of human Hb switching: a possible role of the kit receptor/miR 221-222 complex Erythroid phenotypes associated with KLF1 mutations MicroRNA-15a and -16-1 act via MYB to elevate fetal hemoglobin expression in human trisomy 13 Long-range function of an intergenic retrotransposon Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium Current and future alternative therapies for beta-thalassemia major Customizing the genome as therapy for the β-hemoglobinopathies The therapeutic potential of genome editing for β-thalassemia Towards a new era in medicine: therapeutic genome editing Genomic approaches to identifying targets for treating β hemoglobinopathies Fetal globin gene repressors as drug targets for molecular therapies to treat the β-globinopathies Epigenetic regulation of fetal globin gene expression in adult erythroid cells DNA dynamics and single-molecule biology Role of the transcription factor Bcl11b in development and lymphomagenesis Anemia: progress in molecular mechanisms and therapies Ctip1 Regulates the Balance between Specification of Distinct Projection Neuron Subtypes in Deep Cortical Layers.β-thalassemias: paradigmatic diseases for scientific discoveries and development of innovative therapies 2015 Clinical trials update in sickle cell anemia Erythro-megakaryocytic transcription factors associated with hereditary anemia Mi2β is required for γ-globin gene silencing: temporal assembly of a GATA-1-FOG-1-Mi2 repressor complex in β-YAC transgenic mice Human genetics in rheumatoid arthritis guides a high-throughput drug screen of the CD40 signaling pathway Developmental and species-divergent globin switching are driven by BCL11A Whole exome sequencing identifies novel genes for fetal hemoglobin response to hydroxyurea in children with sickle cell anemia Chemical Inhibition of Histone Deacetylases 1 and 2 Induces Fetal Hemoglobin through Activation of GATA2 Ikaros interacts with P-TEFb and cooperates with GATA-1 to enhance transcription elongation BCL11A enhancer dissection by Cas9-mediated in situ saturating mutagenesis Innovative solutions to novel drug development in mental health Statistical confidence estimation for Hi-C data reveals regulatory chromatin contacts MASL1 induces erythroid differentiation in human erythropoietin-dependent CD34+ cells through the Raf/MEK/ERK pathway BCL11A deletions result in fetal hemoglobin persistence and neurodevelopmental alterations.Hemoglobin switching's surprise: the versatile transcription factor BCL11A is a master repressor of fetal hemoglobin.Hydroxyurea for reducing blood transfusion in non-transfusion dependent beta thalassaemias.Geographical genomics of human leukocyte gene expression variation in southern Morocco A survey of well conserved families of C2H2 zinc-finger genes in Daphnia.PGC-1 coactivator activity is required for murine erythropoiesis.

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P2860

Human fetal hemoglobin expression is regulated by the developmental stage-specific repressor BCL11A.

http://www.wikidata.org/entity/Q39908659

description

2008 nî lūn-bûn

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2008年の論文

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年學術文章

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2008年學術文章

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2008年學術文章

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name

Human fetal hemoglobin express ...... age-specific repressor BCL11A.

@en

Human fetal hemoglobin express ...... age-specific repressor BCL11A.

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type

label

Human fetal hemoglobin express ...... age-specific repressor BCL11A.

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Human fetal hemoglobin express ...... age-specific repressor BCL11A.

@nl

prefLabel

Human fetal hemoglobin express ...... age-specific repressor BCL11A.

@en

Human fetal hemoglobin express ...... age-specific repressor BCL11A.

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Human fetal hemoglobin express ...... age-specific repressor BCL11A.

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Alan B Cantor

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Ben Van Handel

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Guillaume Lettre

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Hanna K A Mikkola

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Jian Xu

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Joel N Hirschhorn

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Stuart H Orkin

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Thomas E Akie

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Tobias F Menne

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Vijay G Sankaran

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1839-1842

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scholarly article

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