Guanidine-acylguanidine bioisosteric approach in the design of radioligands: synthesis of a tritium-labeled N(G)-propionylargininamide ([3H]-UR-MK114) as a highly potent and selective neuropeptide Y Y1 receptor antagonist.

Guanidine-acylguanidine bioisosteric approach in the design of radioligands: synthesis of a tritium-labeled N(G)-propionylargininamide ([3H]-UR-MK114) as a highly potent and selective neuropeptide Y Y1 receptor antagonist.

Item
http://www.wikidata.org/entity/Q39909212
G protein-coupled receptors function as logic gates for nanoparticle binding and cell uptake.The neuropeptide y y(1) receptor: a diagnostic marker? Expression in mcf-7 breast cancer cells is down-regulated by antiestrogens in vitro and in xenografts.Direct arginine modification in native peptides and application to chemical probe development.Novel approaches to screening guanidine derivatives.[³H]UR-MK136: a highly potent and selective radioligand for neuropeptide Y Y₁ receptors.[(3) H]UR-DE257: development of a tritium-labeled squaramide-type selective histamine H2 receptor antagonist.[(3)H]UR-PLN196: a selective nonpeptide radioligand and insurmountable antagonist for the neuropeptide Y Y(2) receptor.Toward Labeled Argininamide-Type NPY Y1 Receptor Antagonists: Identification of a Favorable Propionylation Site in BIBO3304.Application of the guanidine-acylguanidine bioisosteric approach to argininamide-type NPY Y₂ receptor antagonists.Structural basis of ligand binding modes at the neuropeptide Y Y1 receptor.Prototypic 18F-Labeled Argininamide-Type Neuropeptide Y Y1R Antagonists as Tracers for PET Imaging of Mammary Carcinoma.Heterodimerization of Dibenzodiazepinone-Type Muscarinic Acetylcholine Receptor Ligands Leads to Increased M2R Affinity and Selectivity.
P2860

Guanidine-acylguanidine bioisosteric approach in the design of radioligands: synthesis of a tritium-labeled N(G)-propionylargininamide ([3H]-UR-MK114) as a highly potent and selective neuropeptide Y Y1 receptor antagonist.

Item
http://www.wikidata.org/entity/Q39909212
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
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2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
Guanidine-acylguanidine bioiso ...... nthesis of a tritium-labeled N
@nl
Guanidine-acylguanidine bioiso ...... tide Y Y1 receptor antagonist.
@en
type
label
Guanidine-acylguanidine bioiso ...... nthesis of a tritium-labeled N
@nl
Guanidine-acylguanidine bioiso ...... tide Y Y1 receptor antagonist.
@en
prefLabel
Guanidine-acylguanidine bioiso ...... nthesis of a tritium-labeled N
@nl
Guanidine-acylguanidine bioiso ...... tide Y Y1 receptor antagonist.
@en
P1433
P1476
P2093
P304
P31
P356
P407
P433
P478
P50
P577
P698
P356
P1433
P1476
Guanidine-acylguanidine bioiso ...... ptide Y Y1 receptor antagonist
@en
P2093
P304
P31
P356
P407
P433
P478
P50
P577
P698