Guanidine-acylguanidine bioisosteric approach in the design of radioligands: synthesis of a tritium-labeled N(G)-propionylargininamide ([3H]-UR-MK114) as a highly potent and selective neuropeptide Y Y1 receptor antagonist.
about
G protein-coupled receptors function as logic gates for nanoparticle binding and cell uptake.The neuropeptide y y(1) receptor: a diagnostic marker? Expression in mcf-7 breast cancer cells is down-regulated by antiestrogens in vitro and in xenografts.Direct arginine modification in native peptides and application to chemical probe development.Novel approaches to screening guanidine derivatives.[³H]UR-MK136: a highly potent and selective radioligand for neuropeptide Y Y₁ receptors.[(3) H]UR-DE257: development of a tritium-labeled squaramide-type selective histamine H2 receptor antagonist.[(3)H]UR-PLN196: a selective nonpeptide radioligand and insurmountable antagonist for the neuropeptide Y Y(2) receptor.Toward Labeled Argininamide-Type NPY Y1 Receptor Antagonists: Identification of a Favorable Propionylation Site in BIBO3304.Application of the guanidine-acylguanidine bioisosteric approach to argininamide-type NPY Y₂ receptor antagonists.Structural basis of ligand binding modes at the neuropeptide Y Y1 receptor.Prototypic 18F-Labeled Argininamide-Type Neuropeptide Y Y1R Antagonists as Tracers for PET Imaging of Mammary Carcinoma.Heterodimerization of Dibenzodiazepinone-Type Muscarinic Acetylcholine Receptor Ligands Leads to Increased M2R Affinity and Selectivity.
P2860
Q33934981-223E3F2B-24CC-4BB2-B1CF-A86EBE873E44Q34510673-6DF28334-5CB8-4F19-80F9-88710B01835CQ34699009-825E4947-23C3-40D2-9E9E-71C9236A5703Q38164811-11A5FBD5-E15E-4350-9D7B-063FDDA7F4EBQ39512007-1E082B82-093E-4424-8A48-18EB628B2B11Q42001159-0025D347-B8F4-43E6-810F-224A41EB1142Q44483229-8421F27C-23BC-4193-80CC-5304ED32475CQ51743539-E538389C-91A6-49F7-96D8-1D6195757C03Q51767118-31AFD3F8-2218-4E2F-A9EE-B08CA5B96B3FQ52316530-97395F35-BE86-4315-951D-F6301D2B534BQ54933533-2605875B-674C-42B2-980B-A2F06D6CD2FAQ55710562-C38B1716-85B4-4D30-BB86-85AE5D57230D
P2860
Guanidine-acylguanidine bioisosteric approach in the design of radioligands: synthesis of a tritium-labeled N(G)-propionylargininamide ([3H]-UR-MK114) as a highly potent and selective neuropeptide Y Y1 receptor antagonist.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
Guanidine-acylguanidine bioiso ...... nthesis of a tritium-labeled N
@nl
Guanidine-acylguanidine bioiso ...... tide Y Y1 receptor antagonist.
@en
type
label
Guanidine-acylguanidine bioiso ...... nthesis of a tritium-labeled N
@nl
Guanidine-acylguanidine bioiso ...... tide Y Y1 receptor antagonist.
@en
prefLabel
Guanidine-acylguanidine bioiso ...... nthesis of a tritium-labeled N
@nl
Guanidine-acylguanidine bioiso ...... tide Y Y1 receptor antagonist.
@en
P2093
P356
P1476
Guanidine-acylguanidine bioiso ...... ptide Y Y1 receptor antagonist
@en
P2093
Annette G Beck-Sickinger
Armin Buschauer
Günther Bernhardt
Max Keller
Nathalie Pop
P304
P356
10.1021/JM801018U
P407
P577
2008-12-01T00:00:00Z