Differential roles of ArfGAP1, ArfGAP2, and ArfGAP3 in COPI trafficking.
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Regulators and Effectors of Arf GTPases in NeutrophilsCOPI budding within the Golgi stackStructure of the catalytic domain ofPlasmodium falciparumARF GTPase-activating protein (ARFGAP)Platelet-Related Variants Identified by Exomechip Meta-analysis in 157,293 Individuals.ArfGAP1 generates an Arf1 gradient on continuous lipid membranes displaying flat and curved regions.COPI buds 60-nm lipid droplets from reconstituted water-phospholipid-triacylglyceride interfaces, suggesting a tension clamp functionThree homologous ArfGAPs participate in coat protein I-mediated transport.Arf GAPs: gatekeepers of vesicle generation.Models for the functions of Arf GAPs.ARFGAP2 and ARFGAP3 are essential for COPI coat assembly on the Golgi membrane of living cells.Coatomer and dimeric ADP ribosylation factor 1 promote distinct steps in membrane scissionActivation of Gαi at the Golgi by GIV/Girdin imposes finiteness in Arf1 signaling.ArfGAP1 promotes COPI vesicle formation by facilitating coatomer polymerizationGTP-binding protein-like domain of AGAP1 is protein binding site that allosterically regulates ArfGAP protein catalytic activity.The ArfGAP2/3 Glo3 and ergosterol collaborate in transport of a subset of cargoes.Retrograde traffic from the Golgi to the endoplasmic reticulum.Discrete determinants in ArfGAP2/3 conferring Golgi localization and regulation by the COPI coatArf GAP2 is positively regulated by coatomer and cargo.ArfGAP3 regulates the transport of cation-independent mannose 6-phosphate receptor in the post-Golgi compartment.Mechanisms of COPI vesicle formation.Physical aspects of COPI vesicle formation.Retrograde vesicle transport in the Golgi.A sub-nanometre view of how membrane curvature and composition modulate lipid packing and protein recruitment.The ArfGAP protein MoGlo3 regulates the development and pathogenicity of Magnaporthe oryzae.9Å structure of the COPI coat reveals that the Arf1 GTPase occupies two contrasting molecular environments.GAPs in the context of COPI: Enzymes, coat components or both?GAPs: Terminator versus effector functions and the role(s) of ArfGAP1 in vesicle biogenesis.Role of ArfGAP1 in COPI vesicle biogenesis.Recruitment of Arf1-GDP to Golgi by Glo3p-type ArfGAPs is crucial for golgi maintenance and plant growth.Looking inside the cell.ARFGAP; cargo; v-SNAREs and p24 proteins bind nascent COPI complexARFGAP; cargo; vSNARES and p24 proteins bind COPI vesicles at GolgiDistinct role of subcomplexes of the COPI coat in the regulation of ArfGAP2 activity.Scission of COPI and COPII vesicles is independent of GTP hydrolysis.
P2860
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P2860
Differential roles of ArfGAP1, ArfGAP2, and ArfGAP3 in COPI trafficking.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
Differential roles of ArfGAP1, ArfGAP2, and ArfGAP3 in COPI trafficking.
@en
Differential roles of ArfGAP1, ArfGAP2, and ArfGAP3 in COPI trafficking.
@nl
type
label
Differential roles of ArfGAP1, ArfGAP2, and ArfGAP3 in COPI trafficking.
@en
Differential roles of ArfGAP1, ArfGAP2, and ArfGAP3 in COPI trafficking.
@nl
prefLabel
Differential roles of ArfGAP1, ArfGAP2, and ArfGAP3 in COPI trafficking.
@en
Differential roles of ArfGAP1, ArfGAP2, and ArfGAP3 in COPI trafficking.
@nl
P2093
P2860
P356
P1476
Differential roles of ArfGAP1, ArfGAP2, and ArfGAP3 in COPI trafficking.
@en
P2093
Britta Brügger
Carolin Weimer
Felix Wieland
Ingeborg Reckmann
Jörg Moelleken
Priska Eckert
Rainer Beck
P2860
P304
P356
10.1083/JCB.200806140
P407
P577
2008-11-01T00:00:00Z