The C-terminal tail of CRTH2 is a key molecular determinant that constrains Galphai and downstream signaling cascade activation.
about
Altered immune response in mice deficient for the G protein-coupled receptor GPR34PGH1, the precursor for the anti-inflammatory prostaglandins of the 1-series, is a potent activator of the pro-inflammatory receptor CRTH2/DP2High-throughput screening for modulators of protein-protein interactions: use of photonic crystal biosensors and complementary technologies.Decoding signaling and function of the orphan G protein-coupled receptor GPR17 with a small-molecule agonistGPR55 ligands promote receptor coupling to multiple signalling pathways.The allosteric vestibule of a seven transmembrane helical receptor controls G-protein couplingPROBING CANCER SIGNALING WITH RESONANT WAVEGUIDE GRATING BIOSENSORSLabel-Free Receptor Assays.Phenotypic regulation of the sphingosine 1-phosphate receptor miles apart by G protein-coupled receptor kinase 2.GPR55 regulates cannabinoid 2 receptor-mediated responses in human neutrophils.Ligand-receptor interaction platforms and their applications for drug discovery.A cell-permeable inhibitor to trap Gαq proteins in the empty pocket conformation.A biased ligand for OXE-R uncouples Gα and Gβγ signaling within a heterotrimer.The β2-subtype of adrenoceptors mediates inhibition of pro-fibrotic events in human lung fibroblasts.Conjugated linoleic acids mediate insulin release through islet G protein-coupled receptor FFA1/GPR40.A 100K well screen for a muscarinic receptor using the Epic label-free system--a reflection on the benefits of the label-free approach to screening seven-transmembrane receptors.Survey of the 2009 commercial optical biosensor literature.The development of label-free cellular assays for drug discovery.Targeted inhibition of Gq signaling induces airway relaxation in mouse models of asthma.Prostaglandins D2 and E2 have opposite effects on alveolar macrophages infected with Histoplasma capsulatum.Cocaine Effects on Dopaminergic Transmission Depend on a Balance between Sigma-1 and Sigma-2 Receptor Expression.Applying label-free dynamic mass redistribution technology to frame signaling of G protein-coupled receptors noninvasively in living cells.DP1 receptor signaling prevents the onset of intrinsic apoptosis in eosinophils and functions as a transcriptional modulator.Exposure of Intestinal Epithelial Cells to Short- and Long-Chain Fructo-Oligosaccharides and CpG Oligodeoxynucleotides Enhances Peanut-Specific T Helper 1 Polarization.Cannabigerol Action at Cannabinoid CB1 and CB2 Receptors and at CB1-CB2 Heteroreceptor Complexes.Label-Free Biosensors for Cell Biology
P2860
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P2860
The C-terminal tail of CRTH2 is a key molecular determinant that constrains Galphai and downstream signaling cascade activation.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
The C-terminal tail of CRTH2 i ...... signaling cascade activation.
@en
The C-terminal tail of CRTH2 i ...... signaling cascade activation.
@nl
type
label
The C-terminal tail of CRTH2 i ...... signaling cascade activation.
@en
The C-terminal tail of CRTH2 i ...... signaling cascade activation.
@nl
prefLabel
The C-terminal tail of CRTH2 i ...... signaling cascade activation.
@en
The C-terminal tail of CRTH2 i ...... signaling cascade activation.
@nl
P2093
P2860
P356
P1476
The C-terminal tail of CRTH2 i ...... signaling cascade activation.
@en
P2093
Anamarija Kruljac-Letunic
Andree Blaukat
Christel Drewke
Elizabeth Tran
Evi Kostenis
Friederike Krop
Jennifer Whistler
Jesper Mosolff Mathiesen
Jesús Gomeza
Lene Martini
P2860
P304
P356
10.1074/JBC.M806867200
P407
P577
2008-11-14T00:00:00Z