A gene encoding lysine 6-aminotransferase, which forms the beta-lactam precursor alpha-aminoadipic acid, is located in the cluster of cephamycin biosynthetic genes in Nocardia lactamdurans.
about
Molecular regulation of beta-lactam biosynthesis in filamentous fungiThe cefG gene of Cephalosporium acremonium is linked to the cefEF gene and encodes a deacetylcephalosporin C acetyltransferase closely related to homoserine O-acetyltransferaseGenome-minimized Streptomyces host for the heterologous expression of secondary metabolism.The enzymes of β-lactam biosynthesis.Catabolism of lysine in Penicillium chrysogenum leads to formation of 2-aminoadipic acid, a precursor of penicillin biosynthesisMultidomain enzymes involved in peptide synthesis.Involvement of nitrogen-containing compounds in beta-lactam biosynthesis and its control.Biochemical pathways supporting beta-lactam biosynthesis in the springtail Folsomia candida.Regulation and compartmentalization of β-lactam biosynthesis.Inducing effect of diamines on transcription of the cephamycin C genes from the lat and pcbAB promoters in Nocardia lactamdurans.Deletion of the pyc gene blocks clavulanic acid biosynthesis except in glycerol-containing medium: evidence for two different genes in formation of the C3 unit.The pcd gene encoding piperideine-6-carboxylate dehydrogenase involved in biosynthesis of alpha-aminoadipic acid is located in the cephamycin cluster of Streptomyces clavuligerus.The nine genes of the Nocardia lactamdurans cephamycin cluster are transcribed into large mRNAs from three promoters, two of them located in a bidirectional promoter region.A regulatory gene (ccaR) required for cephamycin and clavulanic acid production in Streptomyces clavuligerus: amplification results in overproduction of both beta-lactam compounds.Efficient Transformation of the Cephamycin C Producer Nocardia lactamdurans and Development of Shuttle and Promoter-Probe Cloning Vectors.Genes for a beta-lactamase, a penicillin-binding protein and a transmembrane protein are clustered with the cephamycin biosynthetic genes in Nocardia lactamduransEngineering antibiotic producers to overcome the limitations of classical strain improvement programs.Delta-1-piperideine-6-carboxylate dehydrogenase, a new enzyme that forms alpha-aminoadipate in Streptomyces clavuligerus and other cephamycin C-producing actinomycetes.Overexpression, purification and crystallization of lysine epsilon-aminotransferase (Rv3290c) from Mycobacterium tuberculosis H37Rv.pcd mutants of Streptomyces clavuligerus still produce cephamycin C.Investigation of the biosynthesis of the pipecolate moiety of neuroprotective polyketide meridamycin.
P2860
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P2860
A gene encoding lysine 6-aminotransferase, which forms the beta-lactam precursor alpha-aminoadipic acid, is located in the cluster of cephamycin biosynthetic genes in Nocardia lactamdurans.
description
1991 nî lūn-bûn
@nan
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
1991年论文
@zh
1991年论文
@zh-cn
name
A gene encoding lysine 6-amino ...... enes in Nocardia lactamdurans.
@en
A gene encoding lysine 6-amino ...... enes in Nocardia lactamdurans.
@nl
type
label
A gene encoding lysine 6-amino ...... enes in Nocardia lactamdurans.
@en
A gene encoding lysine 6-amino ...... enes in Nocardia lactamdurans.
@nl
prefLabel
A gene encoding lysine 6-amino ...... enes in Nocardia lactamdurans.
@en
A gene encoding lysine 6-amino ...... enes in Nocardia lactamdurans.
@nl
P2093
P2860
P1476
A gene encoding lysine 6-amino ...... enes in Nocardia lactamdurans.
@en
P2093
P2860
P304
P356
10.1128/JB.173.19.6258-6264.1991
P577
1991-10-01T00:00:00Z