Localization of phosphatidylinositol phosphate kinase IIgamma in kidney to a membrane trafficking compartment within specialized cells of the nephron.
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Phosphoinositides: tiny lipids with giant impact on cell regulationEvolutionarily conserved structural changes in phosphatidylinositol 5-phosphate 4-kinase (PI5P4K) isoforms are responsible for differences in enzyme activity and localizationThe function of phosphatidylinositol 5-phosphate 4-kinase γ (PI5P4Kγ) explored using a specific inhibitor that targets the PI5P-binding siteDistribution and neuronal expression of phosphatidylinositol phosphate kinase IIgamma in the mouse brain.A novel HPLC-based approach makes possible the spatial characterization of cellular PtdIns5P and other phosphoinositides.Genomic tagging reveals a random association of endogenous PtdIns5P 4-kinases IIalpha and IIbeta and a partial nuclear localization of the IIalpha isoform.The emerging role of PtdIns5P: another signalling phosphoinositide takes its place.Exploring phosphatidylinositol 5-phosphate 4-kinase function.PIP4kγ is a substrate for mTORC1 that maintains basal mTORC1 signaling during starvationPhosphatidylinositol 5-phosphate 4-kinase (PIP4K) regulates TOR signaling and cell growth during Drosophila developmentDeletion of the gene Pip4k2c, a novel phosphatidylinositol kinase, results in hyperactivation of the immune systemIn B cells, phosphatidylinositol 5-phosphate 4-kinase-α synthesizes PI(4,5)P2 to impact mTORC2 and Akt signalingLocalization, regulation and function of type II phosphatidylinositol 5-phosphate 4-kinasesLow PIP4K2B expression in human breast tumors correlates with reduced patient survival: A role for PIP4K2B in the regulation of E-cadherin expression.Phosphatidylinositol 4-phosphate 5-kinase Iγ_v6, a new splice variant found in rodents and humans.Nuclear Phosphatidylinositol Signaling: Focus on Phosphatidylinositol Phosphate Kinases and Phospholipases C.Phosphoinositides, Major Actors in Membrane Trafficking and Lipid Signaling Pathways.HPV8-E6 Interferes with Syntenin-2 Expression through Deregulation of Differentiation, Methylation and Phosphatidylinositide-Kinase Dependent MechanismsPhosphatidylinositol 5-phosphate is a second messenger important for cell migration.Regulation of phosphatidylinositol-5-phosphate signaling by Pin1 determines sensitivity to oxidative stress.Inositides--confusion and clarification in Shangri-La.PI5P, PP2A and IER3 Regulate PI3K/AKT SignalingInhibition of PIP4Kγ ameliorates the pathological effects of mutant huntingtin protein.PI3P is phosphorylated to PI(3;4)P2 by PIP4K2/5K1 at the plasma membranePI5P is phosphorylated to PI(4;5)P2 by PIP4K2 dimers at the plasma membrane
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P2860
Localization of phosphatidylinositol phosphate kinase IIgamma in kidney to a membrane trafficking compartment within specialized cells of the nephron.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
Localization of phosphatidylin ...... cialized cells of the nephron.
@en
Localization of phosphatidylin ...... cialized cells of the nephron.
@nl
type
label
Localization of phosphatidylin ...... cialized cells of the nephron.
@en
Localization of phosphatidylin ...... cialized cells of the nephron.
@nl
prefLabel
Localization of phosphatidylin ...... cialized cells of the nephron.
@en
Localization of phosphatidylin ...... cialized cells of the nephron.
@nl
P2093
P2860
P1476
Localization of phosphatidylin ...... cialized cells of the nephron.
@en
P2093
Jonathan H Clarke
Piers C Emson
Robin F Irvine
P2860
P304
P356
10.1152/AJPRENAL.90310.2008
P577
2008-08-27T00:00:00Z