about
Coupling a natural receptor protein with an artificial receptor to afford a semisynthetic fluorescent biosensor.One-pot and sequential organic chemistry on an enzyme surface to tether a fluorescent probe at the proximity of the active site with restoring enzyme activity.Recent progress in strategies for the creation of protein-based fluorescent biosensors.Simultaneous detection of ATP and GTP by covalently linked fluorescent ribonucleopeptide sensors.Design of antiangiogenic hypoxic cell radiosensitizers: 2-nitroimidazoles containing a 2-aminomethylene-4-cyclopentene-1,3-dione moietyConstruction of a library of structurally diverse ribonucleopeptides with catalytic groups.The molecular mechanism of photochemical internalization of cell penetrating peptide-cargo-photosensitizer conjugates.Construction of ratiometric fluorescent sensors by ribonucleopeptides.Double-modification of lectin using two distinct chemistries for fluorescent ratiometric sensing and imaging saccharides in test tube or in cell.Luminescent saccharide biosensor by using lanthanide-bound lectin labeled with fluorescein.Facile conversion of RNA aptamers to modular fluorescent sensors with tunable detection wavelengths.Nucleic-Acid-Templated Enzyme Cascades.A newly designed cell-permeable SNARF derivative as an effective intracellular pH indicator.Synthesis and biological activity of 1-methyl-tryptophan-tirapazamine hybrids as hypoxia-targeting indoleamine 2,3-dioxygenase inhibitors.Latent pH-responsive ratiometric fluorescent cluster based on self-assembled photoactivated SNARF derivatives.Design of novel hypoxia-targeting IDO hybrid inhibitors conjugated with an unsubstituted L-TRP as an IDO affinity moiety.Selective cross-linking of interacting proteins using self-labeling tags.Construction of artificial signal transducers on a lectin surface by post-photoaffinity-labeling modification for fluorescent saccharide biosensors.A protein adaptor to locate a functional protein dimer on molecular switchboard.A chemical biosynthesis design for an antiatherosclerosis drug by acyclic tocopherol intermediate analogue based on "isoprenomics".A peptide nucleic acid (PNA) heteroduplex probe containing an inosine-cytosine base pair discriminates a single-nucleotide difference in RNA.Ultrasound-dependent cytoplasmic internalization of a peptide-sonosensitizer conjugate.TX-2152: a conformationally rigid and electron-rich diyne analogue of FTY720 with in vivo antiangiogenic activity.Target-specific chemical acylation of lectins by ligand-tethered DMAP catalysts.Ratiometric fluorescent biosensor for real-time and label-free monitoring of fine saccharide metabolic pathways.Design, synthesis, and radiosensitizing activities of sugar-hybrid hypoxic cell radiosensitizers.A Diversity-Oriented Library of Fluorophore-Modified Receptors Constructed from a Chemical Library of Synthetic Fluorophores.Design of Modular Protein Tags for Orthogonal Covalent Bond Formation at Specific DNA Sequences.Phosphorylation regulates fibrillation of an aggregation core peptide in the second repeat of microtubule-binding domain of human tau.Positional effects of phosphorylation on the stability and morphology of tau-related amyloid fibrils.DNA Origami Scaffolds as Templates for Functional Tetrameric Kir3 K+ Channels.Synthesis and photophysical properties of new SNARF derivatives as dual emission pH sensors.Design of a hybrid biosensor for enhanced phosphopeptide recognition based on a phosphoprotein binding domain coupled with a fluorescent chemosensor.Ratiometric fluorescence detection of a tag fused protein using the dual-emission artificial molecular probe.Semisynthetic fluorescent sensor proteins based on self-labeling protein tags.A fluorescent lectin array using supramolecular hydrogel for simple detection and pattern profiling for various glycoconjugatesPrenylated acylphloroglucinol derivatives: isoprenomics-based design, syntheses and antioxidative activitiesBoron tracedrug: design, synthesis, and pharmacological activity of phenolic BODIPY-containing antioxidants as traceable next-generation drug modelZinc-finger proteins for site-specific protein positioning on DNA-origami structuresFormation and regulation of fullerene-incorporation in liposomes under the phase transition temperature
P50
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P50
description
hulumtues
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Eiji Nakata
@ast
Eiji Nakata
@en
Eiji Nakata
@es
Eiji Nakata
@nl
Eiji Nakata
@sl
type
label
Eiji Nakata
@ast
Eiji Nakata
@en
Eiji Nakata
@es
Eiji Nakata
@nl
Eiji Nakata
@sl
prefLabel
Eiji Nakata
@ast
Eiji Nakata
@en
Eiji Nakata
@es
Eiji Nakata
@nl
Eiji Nakata
@sl
P1053
G-5523-2013
P106
P21
P31
P3829
P3835
eiji-nakata
P496
0000-0001-9564-6805