Methods for the production of helper-dependent adenoviral vectors.
about
Large-scale production of high-quality helper-dependent adenoviral vectors using adherent cells in cell factories.A novel bicistronic high-capacity gutless adenovirus vector that drives constitutive expression of herpes simplex virus type 1 thymidine kinase and tet-inducible expression of Flt3L for glioma therapeuticsAltering the Ad5 packaging domain affects the maturation of the Ad particles.Modifications of adenovirus hexon allow for either hepatocyte detargeting or targeting with potential evasion from Kupffer cellsLinearized oncolytic adenoviral plasmid DNA delivered by bioreducible polymers.Safety profile, efficacy, and biodistribution of a bicistronic high-capacity adenovirus vector encoding a combined immunostimulation and cytotoxic gene therapy as a prelude to a phase I clinical trial for glioblastomaPreclinical Efficacy and Safety Profile of Allometrically Scaled Doses of Doxycycline Used to Turn "On" Therapeutic Transgene Expression from High-Capacity Adenoviral Vectors in a Glioma ModelHomology Requirements for Efficient, Footprintless Gene Editing at the CFTR Locus in Human iPSCs with Helper-dependent Adenoviral Vectors.Helper-Dependent Adenoviral Vectors.Transient blocking of NK cell function with small molecule inhibitors for helper dependant adenoviral vector-mediated gene delivery.Knockdown of ZNF403 inhibits cell proliferation and induces G2/M arrest by modulating cell-cycle mediators.Adenovirus-retrovirus hybrid vectors achieve highly enhanced tumor transduction and antitumor efficacy in vivoHelper virus-mediated downregulation of transgene expression permits production of recalcitrant helper-dependent adenoviral vector.High-level production of replication-defective human immunodeficiency type 1 virus vector particles using helper-dependent adenovirus vectors.Adenovirus-Vectored Broadly Neutralizing Antibodies Directed Against gp120 Prevent Human Immunodeficiency Virus Type 1 Acquisition in Humanized Mice.Gene Editing with Helper-Dependent Adenovirus Can Efficiently Introduce Multiple Changes Simultaneously over a Large Genomic Region.Pancreatic transduction by helper-dependent adenoviral vectors via intraductal delivery.Engineered LINE-1 retrotransposition in nondividing human neurons.Sustained secretion of anti-tumor necrosis factor α monoclonal antibody from ex vivo genetically engineered dermal tissue demonstrates therapeutic activity in mouse model of rheumatoid arthritis.Orphan receptor GPR158 controls stress-induced depression.Challenges and Prospects for Helper-Dependent Adenoviral Vector-Mediated Gene Therapy.
P2860
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P2860
Methods for the production of helper-dependent adenoviral vectors.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
Methods for the production of helper-dependent adenoviral vectors.
@en
Methods for the production of helper-dependent adenoviral vectors.
@nl
type
label
Methods for the production of helper-dependent adenoviral vectors.
@en
Methods for the production of helper-dependent adenoviral vectors.
@nl
prefLabel
Methods for the production of helper-dependent adenoviral vectors.
@en
Methods for the production of helper-dependent adenoviral vectors.
@nl
P1476
Methods for the production of helper-dependent adenoviral vectors.
@en
P2093
Donna J Palmer
P356
10.1007/978-1-59745-237-3_3
P407
P577
2008-01-01T00:00:00Z