New mutations in C1GALT1C1 in individuals with Tn positive phenotype.
about
Cosmc is an essential chaperone for correct protein O-glycosylationPersistent Tn polyagglutination syndrome during febrile neutropenia: a case report and review of the literatureThe endoplasmic reticulum chaperone Cosmc directly promotes in vitro folding of T-synthase.Identification of distinct glycoforms of IgA1 in plasma from patients with immunoglobulin A (IgA) nephropathy and healthy individualsA novel fluorescent assay for T-synthase activity.Promoters of Human Cosmc and T-synthase Genes Are Similar in Structure, Yet Different in Epigenetic RegulationTight complex formation between Cosmc chaperone and its specific client non-native T-synthase leads to enzyme activity and client-driven dissociation.Epigenetic silencing of the chaperone Cosmc in human leukocytes expressing tn antigenInitiation of GalNAc-type O-glycosylation in the endoplasmic reticulum promotes cancer cell invasiveness.The cytokine-cosmc signaling axis upregulates the tumor-associated carbohydrate antigen Tn.The Tn antigen-structural simplicity and biological complexity.Golgi glycosylation and human inherited diseases.Tn and sialyl-Tn antigens, aberrant O-glycomics as human disease markers.The Cosmc connection to the Tn antigen in cancer.The molecular chaperone Cosmc enhances malignant behaviors of colon cancer cells via activation of Akt and ERK.Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)Defective C1GALT1C1 does not bind C1GALT1C1GALT1 transfers Galactose to the Tn antigen forming Core 1 glycoproteins (T antigens)
P2860
Q28506209-49DE3623-E569-4818-8F29-68FCEA00232DQ33393659-418A0C51-9A72-4CBC-A44C-19B7263C9069Q33593911-BF93B8E4-EA0A-4FB6-AB2E-AE2AD91EB236Q34468379-193AE197-4564-44EC-A9C0-4CF69D11BA20Q34552242-43A9C1CC-D5F0-4069-929E-857CE0367D1FQ35905327-B548B1BE-A563-4999-AE9E-D0B18530201CQ35939823-EE63C979-603A-4890-A2A6-C64274AEF86CQ36436153-1FBBA568-D5C7-458C-B44E-DD0DC2A5C105Q37117895-88EA60E3-4349-4DD5-B7A7-D8BFBCAAC62AQ37641712-FDCC289F-67C1-4855-847D-92581849AE1EQ37831859-0370498D-3056-449D-AB88-B4D9073D7AE8Q37895036-962EB5DE-37E8-4FCD-9DBA-483AA4D9B411Q38121846-8EB92AFF-DF69-4B05-8A9A-6B7BED841D37Q38197051-2CF2D174-7E4A-437D-ABD0-2CD2AE55F0C9Q44392892-4D9CEFE0-C8AD-401F-A12F-000DC47CFA23Q45316547-47916F2F-09B3-4DCC-B3F6-17F2EB99ECF8Q50289226-8C48F548-838A-420E-BA9D-E9B2360C8E8DQ50296355-227CC3B4-E97A-4C11-8F20-AE6A14276FB4
P2860
New mutations in C1GALT1C1 in individuals with Tn positive phenotype.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
New mutations in C1GALT1C1 in individuals with Tn positive phenotype.
@en
New mutations in C1GALT1C1 in individuals with Tn positive phenotype.
@nl
type
label
New mutations in C1GALT1C1 in individuals with Tn positive phenotype.
@en
New mutations in C1GALT1C1 in individuals with Tn positive phenotype.
@nl
prefLabel
New mutations in C1GALT1C1 in individuals with Tn positive phenotype.
@en
New mutations in C1GALT1C1 in individuals with Tn positive phenotype.
@nl
P2093
P2860
P1476
New mutations in C1GALT1C1 in individuals with Tn positive phenotype.
@en
P2093
Belinda K Singleton
Carole Green
David J Anstee
Geoff Daniels
Stephen F Parsons
Vanja Karamatic Crew
P2860
P304
P356
10.1111/J.1365-2141.2008.07215.X
P407
P577
2008-06-05T00:00:00Z