PHA-680626 exhibits anti-proliferative and pro-apoptotic activity on Imatinib-resistant chronic myeloid leukemia cell lines and primary CD34+ cells by inhibition of both Bcr-Abl tyrosine kinase and Aurora kinases.
about
Novel mutant-selective EGFR kinase inhibitors against EGFR T790MHigh chromosome number in hematological cancer cell lines is a negative predictor of response to the inhibition of Aurora B and C by GSK1070916.ENMD-2076 for hematological malignancies.Knockdown of SOD1 sensitizes the CD34+ CML cells to imatinib therapy.Nilotinib: evaluation and analysis of its role in chronic myeloid leukemia.Docetaxel enhances the cytotoxic effects of imatinib on Philadelphia positive human chronic myeloid leukemia cells.
P2860
PHA-680626 exhibits anti-proliferative and pro-apoptotic activity on Imatinib-resistant chronic myeloid leukemia cell lines and primary CD34+ cells by inhibition of both Bcr-Abl tyrosine kinase and Aurora kinases.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
PHA-680626 exhibits anti-proli ...... ine kinase and Aurora kinases.
@en
PHA-680626 exhibits anti-proli ...... ine kinase and Aurora kinases.
@nl
type
label
PHA-680626 exhibits anti-proli ...... ine kinase and Aurora kinases.
@en
PHA-680626 exhibits anti-proli ...... ine kinase and Aurora kinases.
@nl
prefLabel
PHA-680626 exhibits anti-proli ...... ine kinase and Aurora kinases.
@en
PHA-680626 exhibits anti-proli ...... ine kinase and Aurora kinases.
@nl
P2093
P921
P1433
P1476
PHA-680626 exhibits anti-proli ...... ine kinase and Aurora kinases.
@en
P2093
Artur Gontarewicz
Carsten Bokemeyer
Gunhild Keller
Jens Panse
Jürgen Moll
Philippe Schafhausen
Stefan Balabanov
Tim H Brümmendorf
Walter Fiedler
P304
P356
10.1016/J.LEUKRES.2008.04.012
P577
2008-06-02T00:00:00Z