about
Novel myosin-based therapies for congenital cardiac and skeletal myopathiesFactors underlying the early limb muscle weakness in acute quadriplegic myopathy using an experimental ICU porcine modelMyofibrillar myopathy caused by a mutation in the motor domain of mouse MyHC IIbPointed-end capping by tropomodulin modulates actomyosin crossbridge formation in skeletal muscle fibers.Impaired adaptive response to mechanical overloading in dystrophic skeletal muscleAberrant post-translational modifications compromise human myosin motor function in old age.Disrupted myosin cross-bridge cycling kinetics triggers muscle weakness in nebulin-related myopathy.Congenital myopathy-causing tropomyosin mutations induce thin filament dysfunction via distinct physiological mechanisms.Ryanodine receptor fragmentation and sarcoplasmic reticulum Ca2+ leak after one session of high-intensity interval exercise.Tropomodulin 1 directly controls thin filament length in both wild-type and tropomodulin 4-deficient skeletal muscle.Myopathy-inducing mutation H40Y in ACTA1 hampers actin filament structure and functionModulating myosin restores muscle function in a mouse model of nemaline myopathy.Dystrophin restoration therapy improves both the reduced excitability and the force drop induced by lengthening contractions in dystrophic mdx skeletal muscle.Thin filament proteins mutations associated with skeletal myopathies: defective regulation of muscle contraction.Skeletal muscle: a brief review of structure and function.Current and future therapeutic approaches to the congenital myopathies.Distinct underlying mechanisms of limb and respiratory muscle fiber weaknesses in nemaline myopathy.Maintenance of muscle mass, fiber size, and contractile function in mice lacking the Z-disc protein myotilin.The fraction of strongly bound cross-bridges is increased in mice that carry the myopathy-linked myosin heavy chain mutation MYH4L342Q.Exploring the Role of PGC-1α in Defining Nuclear Organisation in Skeletal Muscle Fibres.Sparing of muscle mass and function by passive loading in an experimental intensive care unit model.Skeletal and cardiac α-actin isoforms differently modulate myosin cross-bridge formation and myofibre force production.Myofilament lattice structure in presence of a skeletal myopathy-related tropomyosin mutation.Myostatin inhibition using mRK35 produces skeletal muscle growth and tubular aggregate formation in wild type and TgACTA1D286G nemaline myopathy mice.Congenital myopathies: disorders of excitation-contraction coupling and muscle contraction.Sexually dimorphic myofilament function in a mouse model of nemaline myopathy.The influence of ageing on the force-velocity-power characteristics of human elbow flexor muscles.X-ray recordings reveal how a human disease-linked skeletal muscle α-actin mutation leads to contractile dysfunction.SIRT1 regulates nuclear number and domain size in skeletal muscle fibers.Reducing dynamin 2 (DNM2) rescues -related dominant centronuclear myopathyPrelamin A causes aberrant myonuclear arrangement and results in muscle fiber weaknessMolecular Consequences of the Myopathy-Related D286G Mutation on Actin FunctionChanges in mechanical properties of human plantar flexor muscles in ageingEffects of a preferential myosin loss on Ca2+ activation of force generation in single human skeletal muscle fibresDefective regulation of contractile function in muscle fibres carrying an E41K beta-tropomyosin mutationEffect of strength training on musculotendinous stiffness in elderly individualsMechanisms underlying the sparing of masticatory versus limb muscle function in an experimental critical illness modelSingle skeletal muscle fiber behavior after a quick stretch in young and older men: a possible explanation of the relative preservation of eccentric force in old ageChanges in muscle and joint elasticity following long-term strength training in old agePreferential skeletal muscle myosin loss in response to mechanical silencing in a novel rat intensive care unit model: underlying mechanisms
P50
Q26740449-D27C5AFE-38D5-4DB7-ABBF-C6A20047F9AFQ28478575-CA5EB579-5CD3-4AF5-A9A3-B4DA2748DCFFQ28513616-EFEDE4BD-5D69-4F1E-A4D8-A1E5C3B041F6Q30560184-D8D5804F-4525-40A0-A1F9-AD9122EE97AFQ34237002-BBB8336B-BE82-4897-BFEC-D2849ED49167Q35192135-87AF5844-A430-43D6-8078-23548CD67077Q35559068-43C279F3-E73E-40AC-8BAB-895F44E17FE5Q36283381-AF703D80-228E-4872-87B2-1FBCDBE5E1C0Q36394470-97B7CE6E-01C7-4C8E-BF05-7C491C987C97Q36398941-E24912F5-57D5-42E7-B894-36BE21E924A1Q36971956-FCE771A0-4E31-4942-BB61-01B093F8375DQ37107119-AD04858F-6CFF-429F-B760-BA527A26DB41Q37111473-F6FBDCA7-B895-4D08-A49F-2653E396C619Q37198630-0C69EBF0-A42F-4759-A04A-6086D674FC12Q38258053-5663D587-EA34-4F04-A613-6468BE1FFC57Q38832207-A67D7799-F0B5-49E6-A81C-B21619DB5D30Q39422476-08516DC6-9B9E-4953-B800-0A2CD79AD76AQ39979500-B13A8B5A-2D8A-4D6E-A7ED-90471AEFDBC8Q40053432-2328B99A-BD5B-42D1-B674-E006C3E7343BQ42319819-AC269640-B90B-4DC5-AB76-808792EB5131Q44539075-FBC984B6-D2AC-4969-BC5E-FFD1A7D9B9EEQ46376624-392795EA-5FAA-4F1D-8DF2-FBC83D8DFE98Q46849807-6CF36222-D5AB-4F7D-9988-0EC0B0EDD85CQ47205244-8266112B-2E2F-4261-BE89-D4B79E23D580Q49388884-395752D7-8A05-4545-84A3-F9EFF42037A7Q51694970-CA7D33FF-D0DC-43CD-9AEF-3A15FDD69CD9Q52019274-EC29C394-30B7-4921-919A-601BEA5B91D0Q53331996-1693403E-71E6-401C-A667-AFF71FF479F5Q55262982-D76AAB66-01A8-4D02-A9DF-3F93DC4C5D7EQ57022925-015C9FF7-B97D-4E04-88F2-2E9D5A53817EQ57029355-835DAD1E-7EB6-4C80-BBC9-711249666DEEQ60047025-2D75A005-C108-401C-98F3-A20ED44BBDF4Q79809480-57CD02A0-B105-4B65-BAF7-4155A0E2B5ABQ80619599-E6518671-2067-4051-8EB9-5557C0A246DEQ81107472-D2C45DC5-2D11-4622-9694-A4B0476F16AAQ81384181-18CA096C-BA6D-4A06-997B-4CE7A3669A92Q82087771-0F0931DE-1701-41BC-AE21-71AFB7F72E58Q83171975-5AAF3FD0-7FC1-4CBC-9EE1-719F04F4FD2BQ83311976-935C4508-AE38-4B6C-813D-F99C2B700FE0Q83410838-B6196DE9-6AED-484E-857A-C222288C0098
P50
description
hulumtues
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Julien Ochala
@ast
Julien Ochala
@en
Julien Ochala
@es
Julien Ochala
@nl
Julien Ochala
@sl
type
label
Julien Ochala
@ast
Julien Ochala
@en
Julien Ochala
@es
Julien Ochala
@nl
Julien Ochala
@sl
prefLabel
Julien Ochala
@ast
Julien Ochala
@en
Julien Ochala
@es
Julien Ochala
@nl
Julien Ochala
@sl
P1053
K-4120-2017
P106
P1153
6507058079
P21
P31
P3829
P496
0000-0002-6358-2920