7-Bromoindirubin-3'-oxime uncovers a serine protease-mediated paradigm of necrotic cell death.
about
Apoptotic DNA degradation into oligonucleosomal fragments, but not apoptotic nuclear morphology, relies on a cytosolic pool of DFF40/CAD endonuclease6-Bromoindirubin-3'-oxime inhibits JAK/STAT3 signaling and induces apoptosis of human melanoma cells.An Early and Robust Activation of Caspases Heads Cells for a Regulated Form of Necrotic-like Cell Death.Caspase-activated DNase is necessary and sufficient for oligonucleosomal DNA breakdown, but not for chromatin disassembly during caspase-dependent apoptosis of LN-18 glioblastoma cells.A high-throughput image-based screen for the identification of Bax/Bak-independent caspase activators against drug-resistant cancer cells.Chromatin collapse during caspase-dependent apoptotic cell death requires DNA fragmentation factor, 40-kDa subunit-/caspase-activated deoxyribonuclease-mediated 3'-OH single-strand DNA breaks.Indirubin-3-monoxime exhibits anti-inflammatory properties by down-regulating NF-κB and JNK signaling pathways in lipopolysaccharide-treated RAW264.7 cells.Induction of atypical cell death in thyroid carcinoma cells by the indirubin derivative 7-bromoindirubin-3'-oxime (7BIO).
P2860
Q28910429-FBB2273E-9A23-4469-A36B-4B1E06D0C8B7Q35022350-D014CB66-F4EB-45A3-AD40-BCBE982E11BDQ38858686-78AED66F-31A5-4746-9019-67CE7960B09CQ38994066-52C15EEF-D3ED-444B-B795-E377DCFD522EQ39063882-C9CD6368-DE6C-4D54-A766-3957D62C0D82Q39190509-64B1EF70-7C1C-4EB9-A829-7AAEF8636299Q39424757-0E0085A3-4AE3-43D3-8831-5E66C4DD57B8Q43224690-29EEED10-0261-4B4C-B3F3-1641C1050F54
P2860
7-Bromoindirubin-3'-oxime uncovers a serine protease-mediated paradigm of necrotic cell death.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
7-Bromoindirubin-3'-oxime unco ...... radigm of necrotic cell death.
@en
7-Bromoindirubin-3'-oxime unco ...... radigm of necrotic cell death.
@nl
type
label
7-Bromoindirubin-3'-oxime unco ...... radigm of necrotic cell death.
@en
7-Bromoindirubin-3'-oxime unco ...... radigm of necrotic cell death.
@nl
prefLabel
7-Bromoindirubin-3'-oxime unco ...... radigm of necrotic cell death.
@en
7-Bromoindirubin-3'-oxime unco ...... radigm of necrotic cell death.
@nl
P2093
P50
P1476
7-Bromoindirubin-3'-oxime unco ...... aradigm of necrotic cell death
@en
P2093
Jacint Boix
Laurent Meijer
Xènia Garrofé-Ochoa
P356
10.1016/J.BCP.2008.03.023
P407
P577
2008-04-11T00:00:00Z