Theiler's virus-induced demyelination: prevention by immunosuppression.
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Virus-mediated autoimmunity in Multiple Sclerosis.Infection as an Environmental Trigger of Multiple Sclerosis Disease ExacerbationUltrastructural immunohistochemical localization of virus in acute and chronic demyelinating Theiler's virus infectionIs Multiple Sclerosis an Autoimmune Disease?Axonal loss results in spinal cord atrophy, electrophysiological abnormalities and neurological deficits following demyelination in a chronic inflammatory model of multiple sclerosisSpontaneous remyelination following extensive demyelination is associated with improved neurological function in a viral model of multiple sclerosis.Characterization of and functional antigen presentation by central nervous system mononuclear cells from mice infected with Theiler's murine encephalomyelitis virusRole of individual T-cell epitopes of Theiler's virus in the pathogenesis of demyelination correlates with the ability to induce a Th1 response.Humoral and cell-mediated immune mechanisms in the production of pathology in avirulent Semliki Forest virus encephalitisSusceptibility of inbred mice to chronic central nervous system infection by Theiler's murine encephalomyelitis virus.Transgenic expression of Theiler's murine encephalomyelitis virus genes in H-2(b) mice inhibits resistance to virus-induced demyelinationContrasting effects of immunosuppression on Theiler's virus infection in miceOverexpression of caspase 1 in apoptosis-resistant astrocytes infected with the BeAn Theiler's virus.Transgenic expression of viral capsid proteins predisposes to axonal injury in a murine model of multiple sclerosisInjection of the sciatic nerve with TMEV: a new model for peripheral nerve demyelination.Quantitative ultrastructural analysis of a single spinal cord demyelinated lesion predicts total lesion load, axonal loss, and neurological dysfunction in a murine model of multiple sclerosisThe relationship between viral RNA, myelin-specific mRNAs, and demyelination in central nervous system disease during Theiler's virus infection.Viral infection and dissemination through the olfactory pathway and the limbic system by Theiler's virusGamma interferon is critical for resistance to Theiler's virus-induced demyelination.Theiler's virus persistence and demyelination in major histocompatibility complex class II-deficient miceRemyelination during remission in Theiler's virus infectionMurine central nervous system infection by a viral temperature-sensitive mutant: a subacute disease leading to demyelination.Role of macrophages during Theiler's virus infection.Deletion of beta-2-microglobulin ameliorates spinal cord lesion load and promotes recovery of brainstem NAA levels in a murine model of multiple sclerosisAutoimmune and virus-induced demyelinating diseases. A review.Differential virus replication, cytokine production, and antigen-presenting function by microglia from susceptible and resistant mice infected with Theiler's virusUncoupled relationship between demyelination and primary infection of myelinating cells in Theiler's virus encephalomyelitis.Biochemistry of Theiler's murine encephalomyelitis virus isolated from acutely infected mouse brain: identification of a previously unreported polypeptide.Anticapsid immunity level, not viral persistence level, correlates with the progression of Theiler's virus-induced demyelinating disease in viral P1-transgenic mice.The interaction of two groups of murine genes determines the persistence of Theiler's virus in the central nervous systemMajor histocompatibility complex-conferred resistance to Theiler's virus-induced demyelinating disease is inherited as a dominant trait in B10 congenic miceIdentification of a locus on mouse chromosome 3 involved in differential susceptibility to Theiler's murine encephalomyelitis virus-induced demyelinating disease.Cytotoxic T cells isolated from the central nervous systems of mice infected with Theiler's virus.Localization of a neutralization site of Theiler's murine encephalomyelitis viruses.Demyelinating lesions due to Theiler's virus are associated with ongoing central nervous system infectionTheiler's virus infection in nude mice: viral RNA in vascular endothelial cells.Monoclonal anti-I-A antibody reverses chronic paralysis and demyelination in Theiler's virus-infected mice: critical importance of timing of treatment.Neutralizing monoclonal antibodies to Theiler's murine encephalomyelitis virusesTransgenic expression of non-structural genes of Theiler's virus suppresses initial viral replication and pathogenesis of demyelination.Relationship between host age and persistence of Theiler's virus in the central nervous system of mice.
P2860
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P2860
Theiler's virus-induced demyelination: prevention by immunosuppression.
description
1976 nî lūn-bûn
@nan
1976年の論文
@ja
1976年学术文章
@wuu
1976年学术文章
@zh-cn
1976年学术文章
@zh-hans
1976年学术文章
@zh-my
1976年学术文章
@zh-sg
1976年學術文章
@yue
1976年學術文章
@zh
1976年學術文章
@zh-hant
name
Theiler's virus-induced demyelination: prevention by immunosuppression.
@en
Theiler's virus-induced demyelination: prevention by immunosuppression.
@nl
type
label
Theiler's virus-induced demyelination: prevention by immunosuppression.
@en
Theiler's virus-induced demyelination: prevention by immunosuppression.
@nl
prefLabel
Theiler's virus-induced demyelination: prevention by immunosuppression.
@en
Theiler's virus-induced demyelination: prevention by immunosuppression.
@nl
P356
P1433
P1476
Theiler's virus-induced demyelination: prevention by immunosuppression.
@en
P2093
Dal Canto MC
P356
10.1126/SCIENCE.176726
P407
P577
1976-04-01T00:00:00Z