Cellular uptake, cytotoxicity, and metabolic profiling of human cancer cells treated with ruthenium(II) polypyridyl complexes [Ru(bpy)2(N--N)]Cl2 with N--N=bpy, phen, dpq, dppz, and dppn.
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Ru-TAP complexes and DNA: from photo-induced electron transfer to gene photo-silencing in living cellsBinding of a designed anti-cancer drug to the central cavity of an RNA three-way junctionChemical Swarming: Depending on Concentration, an Amphiphilic Ruthenium Polypyridyl Complex Induces Cell Death via Two Different MechanismsCellular and cell-free studies of catalytic DNA cleavage by ruthenium polypyridyl complexes containing redox-active intercalating ligands.Cytotoxic effects of the compound cis-tetraammine(oxalato)ruthenium(III) dithionate on K-562 human chronic myelogenous leukemia cells.Library of second-generation cycloruthenated compounds and evaluation of their biological properties as potential anticancer drugs: passing the nanomolar barrier.Ruthenium-based chemotherapeutics: are they ready for prime time?Effects of chirality on the intracellular localization of binuclear ruthenium(II) polypyridyl complexes.The effect of novel rhenium compounds on lymphosarcoma, PC-3 prostate and myeloid leukemia cancer cell lines and an investigation on the DNA binding properties of one of these compounds through electronic spectroscopy.Synthesis and characterization of mixed-ligand diimine-piperonal thiosemicarbazone complexes of ruthenium(II): Biophysical investigations and biological evaluation as anticancer and antibacterial agents.Solid-phase synthesis as a platform for the discovery of new ruthenium complexes for efficient release of photocaged ligands with visible light.Background-free in-vivo Imaging of Vitamin C using Time-gateable Responsive ProbeUltrafast in cellulo photoinduced dynamics processes of the paradigm molecular light switch [Ru(bpy)2dppz](2.).Dual-emissive nanoarchitecture of lanthanide-complex-modified silica particles for in vivo ratiometric time-gated luminescence imaging of hypochlorous acid.Small cationic antimicrobial peptides delocalize peripheral membrane proteins.Development of a novel lysosome-targetable time-gated luminescence probe for ratiometric and luminescence lifetime detection of nitric oxide in vivo.Complexes in context: attempting to control the cellular uptake and localisation of rhenium fac-tricarbonyl polypyridyl complexes.Ruthenium(II) polypyridyl complexes and DNA--from structural probes to cellular imaging and therapeutics.Insights into the in vitro Anticancer Effects of Diruthenium-1.Photochemistry of ruthenium(ii) complexes based on 1,4,5,8-tetraazaphenanthrene and 2,2'-bipyrazine: a comprehensive experimental and theoretical study.A Cytostatic Ruthenium(II)-Platinum(II) Bis(terpyridyl) Anticancer Complex That Blocks Entry into S Phase by Up-regulating p27(KIP1).Ruthenium(ii) complexes with dppz: from molecular photoswitch to biological applications.DNA-binding and cytotoxic efficacy studies of organorhenium pentylcarbonate compounds.Bis(dipyridophenazine)(2-(2'-pyridyl)pyrimidine-4-carboxylic acid)ruthenium(II) hexafluorophosphate: a lesson in stubbornness.A bis(dipyridophenazine)(2-(2-pyridyl)pyrimidine-4-carboxylic acid)ruthenium(II) complex with anticancer action upon photodeprotection.A deadly organometallic luminescent probe: anticancer activity of a ReI bisquinoline complex.Mitochondria are the primary target in the induction of apoptosis by chiral ruthenium(II) polypyridyl complexes in cancer cells.A dinuclear ruthenium(II) complex as a one- and two-photon luminescent probe for biological Cu(2+) detection.Cytotoxicity, apoptosis, cell cycle arrest, reactive oxygen species, mitochondrial membrane potential, and Western blotting analysis of ruthenium(II) complexes.Synthesis, characterization, and DNA binding, photocleavage, cytotoxicity, cellular uptake, apoptosis, and on-off light switching studies of Ru(II) mixed-ligand complexes containing 7-fluorodipyrido[3,2-a:2',3'-c]phenazine.The induction of mitochondria-mediated apoptosis in cancer cells by ruthenium(II) asymmetric complexes.Regression of lung cancer by hypoxia-sensitizing ruthenium polypyridyl complexes.Ruthenium oligonucleotides, targeting HPV16 E6 oncogene, inhibit the growth of cervical cancer cells under illumination by a mechanism involving p53.From catalysts to bioactive organometallics: do Grubbs catalysts trigger biological effects?Synthesis, structures, cellular uptake and apoptosis-inducing properties of highly cytotoxic ruthenium-Norharman complexes.Two-photon induced luminescence, singlet oxygen generation, cellular uptake and photocytotoxic properties of amphiphilic Ru(II) polypyridyl-porphyrin conjugates as potential bifunctional photodynamic therapeutic agents.Mechanism of cytotoxicity and cellular uptake of lipophilic inert dinuclear polypyridylruthenium(II) complexes.The antimicrobial activity of inert oligonuclear polypyridylruthenium(II) complexes against pathogenic bacteria, including MRSA.Ruthenium(II) metallo-intercalators: DNA imaging and cytotoxicity.A 'Sleeping Trojan Horse' which transports metal ions into cells, localises in nucleoli, and has potential for bimodal fluorescence/PET imaging.
P2860
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P2860
Cellular uptake, cytotoxicity, and metabolic profiling of human cancer cells treated with ruthenium(II) polypyridyl complexes [Ru(bpy)2(N--N)]Cl2 with N--N=bpy, phen, dpq, dppz, and dppn.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
Cellular uptake, cytotoxicity, ...... py, phen, dpq, dppz, and dppn.
@en
Cellular uptake, cytotoxicity, ...... py, phen, dpq, dppz, and dppn.
@nl
type
label
Cellular uptake, cytotoxicity, ...... py, phen, dpq, dppz, and dppn.
@en
Cellular uptake, cytotoxicity, ...... py, phen, dpq, dppz, and dppn.
@nl
prefLabel
Cellular uptake, cytotoxicity, ...... py, phen, dpq, dppz, and dppn.
@en
Cellular uptake, cytotoxicity, ...... py, phen, dpq, dppz, and dppn.
@nl
P2093
P356
P1433
P1476
Cellular uptake, cytotoxicity, ...... py, phen, dpq, dppz, and dppn.
@en
P2093
Hamed Alborzinia
Johanna Niesel
Ronald Gust
Stefan Wölfl
Ulrich Schatzschneider
P304
P356
10.1002/CMDC.200800039
P577
2008-07-01T00:00:00Z