Synthesis and biological evaluation of aminomethylphenol derivatives as inhibitors of the murine GABA transporters mGAT1-mGAT4.

Synthesis and biological evaluation of aminomethylphenol derivatives as inhibitors of the murine GABA transporters mGAT1-mGAT4.

Item
http://www.wikidata.org/entity/Q39994283
Deletion of the γ-aminobutyric acid transporter 2 (GAT2 and SLC6A13) gene in mice leads to changes in liver and brain taurine contentsLibrary screening by means of mass spectrometry (MS) binding assays-exemplarily demonstrated for a pseudostatic library addressing γ-aminobutyric acid (GABA) transporter 1 (GAT1).Dynamic combinatorial chemistry: a tool to facilitate the identification of inhibitors for protein targets.Development and validation of an LC-ESI-MS/MS quantification method for a potential γ-aminobutyric acid transporter 3 (GAT3) marker and its application in preliminary MS binding assays.Generation and screening of oxime libraries addressing the neuronal GABA transporter GAT1.GABA transporters as targets for new drugs.Different Binding Modes of Small and Large Binders of GAT1.Classification of High-Activity Tiagabine Analogs by Binary QSAR Modeling.Development of Highly Potent GAT1 Inhibitors: Synthesis of Nipecotic Acid Derivatives with N-Arylalkynyl Substituents.Structure, Function, and Modulation of γ-Aminobutyric Acid Transporter 1 (GAT1) in Neurological Disorders: A Pharmacoinformatic ProspectiveDevelopment of an (S)-1-{2-[Tris(4-methoxyphenyl)methoxy]ethyl}piperidine-3-carboxylic acid [(S)-SNAP-5114] Carba Analogue Inhibitor for Murine γ-Aminobutyric Acid Transporter Type 4
P2860

Synthesis and biological evaluation of aminomethylphenol derivatives as inhibitors of the murine GABA transporters mGAT1-mGAT4.

Item
http://www.wikidata.org/entity/Q39994283
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
Synthesis and biological evalu ...... GABA transporters mGAT1-mGAT4.
@en
Synthesis and biological evalu ...... GABA transporters mGAT1-mGAT4.
@nl
type
label
Synthesis and biological evalu ...... GABA transporters mGAT1-mGAT4.
@en
Synthesis and biological evalu ...... GABA transporters mGAT1-mGAT4.
@nl
prefLabel
Synthesis and biological evalu ...... GABA transporters mGAT1-mGAT4.
@en
Synthesis and biological evalu ...... GABA transporters mGAT1-mGAT4.
@nl
P1433
P1476
P2093
P304
P31
P356
P433
P478
P577
P698
P356
P1433
P1476
Synthesis and biological evalu ...... GABA transporters mGAT1-mGAT4.
@en
P2093
P304
P31
P356
10.1016/J.EJMECH.2008.01.005
P433
P478
P577
P698