Immune response against frameshift-induced neopeptides in HNPCC patients and healthy HNPCC mutation carriers.
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Current hypotheses on how microsatellite instability leads to enhanced survival of Lynch Syndrome patientsSelTarbase, a database of human mononucleotide-microsatellite mutations and their potential impact to tumorigenesis and immunologyMolecular Subtypes and Personalized Therapy in Metastatic Colorectal CancerAssociation of Fusobacterium nucleatum with immunity and molecular alterations in colorectal cancerLynch syndrome and Lynch syndrome mimics: The growing complex landscape of hereditary colon cancerOpportunities for immunotherapy in microsatellite instable colorectal cancerThe promise of PD-1 inhibitors in gastro-esophageal cancers: microsatellite instability vs. PD-L1Biomarkers for immune therapy in colorectal cancer: mismatch-repair deficiency and othersGenetics and Genetic Biomarkers in Sporadic Colorectal CancerTumor infiltrating lymphocytes: an intriguing player in the survival of colorectal cancer patients.T cell therapy targeting a public neoantigen in microsatellite instable colon cancer reduces in vivo tumor growth.Molecular classifications of gastric cancers: Novel insights and possible future applications.Epithelial to mesenchymal transition is impaired in colon cancer cells with microsatellite instability.Nonsense mediated decay resistant mutations are a source of expressed mutant proteins in colon cancer cell lines with microsatellite instability.Influence of race on microsatellite instability and CD8+ T cell infiltration in colon cancer.Genomic and epigenetic instability in colorectal cancer pathogenesis.Intraepithelial effector (CD3+)/regulatory (FoxP3+) T-cell ratio predicts a clinical outcome of human colon carcinomaLack of HLA class II antigen expression in microsatellite unstable colorectal carcinomas is caused by mutations in HLA class II regulatory genes.Semiallogenic fusions of MSI(+) tumor cells and activated B cells induce MSI-specific T cell responses5-Fluorouracil response in a large panel of colorectal cancer cell lines is associated with mismatch repair deficiency.An MSI tumor specific frameshift mutation in a coding microsatellite of MSH3 encodes for HLA-A0201-restricted CD8+ cytotoxic T cell epitopesIdentification of an MSI-H tumor-specific cytotoxic T cell epitope generated by the (-1) frame of U79260(FTO).FHL2 expression in peritumoural fibroblasts correlates with lymphatic metastasis in sporadic but not in HNPCC-associated colon cancer.Tumor characteristics as an analytic tool for classifying genetic variants of uncertain clinical significance.Development of sporadic microsatellite instability in colorectal tumors involves hypermethylation at methylated-in-tumor loci in adenomaSerum antibodies against frameshift peptides in microsatellite unstable colorectal cancer patients with Lynch syndrome.Tumour-infiltrating T-cell subsets, molecular changes in colorectal cancer, and prognosis: cohort study and literature reviewRegulatory T lymphocytes are associated with less aggressive histologic features in microsatellite-unstable colorectal cancers.Reactivity against microsatellite instability-induced frameshift mutations in patients with inflammatory bowel disease.Tumor-infiltrating lymphocytes in colorectal cancers with microsatellite instability are correlated with the number and spectrum of frameshift mutations.Mismatch repair-deficient crypt foci in Lynch syndrome--molecular alterations and association with clinical parameters.T cells and adoptive immunotherapy: recent developments and future prospects in gastrointestinal oncology.Cancer immunology--analysis of host and tumor factors for personalized medicine.High lymph node yield is related to microsatellite instability in colon cancerBacterially-Associated Transcriptional Remodelling in a Distinct Genomic Subtype of Colorectal Cancer Provides a Plausible Molecular Basis for Disease Development.Somatic mutations of the coding microsatellites within the beta-2-microglobulin gene in mismatch repair-deficient colorectal cancers and adenomas.Low density of FOXP3-positive T cells in normal colonic mucosa is related to the presence of beta2-microglobulin mutations in Lynch syndrome-associated colorectal cancer.Molecular Biomarkers in the Personalized Treatment of Colorectal Cancer.Genomic Correlates of Immune-Cell Infiltrates in Colorectal CarcinomaMolecular and genetic properties of tumors associated with local immune cytolytic activity.
P2860
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P2860
Immune response against frameshift-induced neopeptides in HNPCC patients and healthy HNPCC mutation carriers.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
Immune response against frames ...... althy HNPCC mutation carriers.
@en
Immune response against frames ...... althy HNPCC mutation carriers.
@nl
type
label
Immune response against frames ...... althy HNPCC mutation carriers.
@en
Immune response against frames ...... althy HNPCC mutation carriers.
@nl
prefLabel
Immune response against frames ...... althy HNPCC mutation carriers.
@en
Immune response against frames ...... althy HNPCC mutation carriers.
@nl
P2093
P1433
P1476
Immune response against frames ...... althy HNPCC mutation carriers.
@en
P2093
Axel Benner
Hanns Peter Knaebel
Magnus von Knebel Doeberitz
Matthias Kloor
Michael Linnebacher
Mirjam Tariverdian
Peter Kienle
Susanne Eiermann
Yvette Schwitalle
P304
P356
10.1053/J.GASTRO.2008.01.015
P407
P577
2008-01-11T00:00:00Z