Developmental study of fragile X syndrome using human embryonic stem cells derived from preimplantation genetically diagnosed embryos.
about
P1343
Studying early lethality of 45,XO (Turner's syndrome) embryos using human embryonic stem cellsTranscriptional Reactivation of the FMR1 Gene. A Possible Approach to the Treatment of the Fragile X SyndromeHuman Embryonic Stem Cells: A Model for the Study of Neural Development and Neurological DiseasesThe Application of Human iPSCs in Neurological Diseases: From Bench to BedsideModelling human disease with pluripotent stem cellsDisease modeling and cell based therapy with iPSC: future therapeutic option with fast and safe applicationRepeat-mediated genetic and epigenetic changes at the FMR1 locus in the Fragile X-related disordersModeling diseases of noncoding unstable repeat expansions using mutant pluripotent stem cells.Ups and Downs: Mechanisms of Repeat Instability in the Fragile X-Related DisordersModeling Fragile X Syndrome Using Human Pluripotent Stem CellsThe Use of Induced Pluripotent Stem Cell Technology to Advance Autism Research and TreatmentThe promise and perils of HDAC inhibitors in neurodegenerationGenotype-specific differences between mouse CNS stem cell lines expressing frontotemporal dementia mutant or wild type human tauRole of CTCF protein in regulating FMR1 locus transcriptionFamilial Dysautonomia (FD) Human Embryonic Stem Cell Derived PNS Neurons Reveal that Synaptic Vesicular and Neuronal Transport Genes Are Directly or Indirectly Affected by IKBKAP DownregulationStem cells and modeling of autism spectrum disorders.From FMRP function to potential therapies for fragile X syndrome.CGG repeat in the FMR1 gene: size mattersZebularine regulates early stages of mESC differentiation: effect on cardiac commitment.The impact of local genome sequence on defining heterochromatin domains.The bioethics of stem cell research and therapyProgress toward the clinical application of patient-specific pluripotent stem cellsFour decades of leading-edge research in the reproductive and developmental sciences: the Infant Primate Research Laboratory at the University of Washington National Primate Research Center.Human embryonic stem cells from aneuploid blastocysts identified by pre-implantation genetic screening.Knockdown of Fanconi anemia genes in human embryonic stem cells reveals early developmental defects in the hematopoietic lineage.iPSC-derived forebrain neurons from FXS individuals show defects in initial neurite outgrowthEpigenetic characterization of the FMR1 gene and aberrant neurodevelopment in human induced pluripotent stem cell models of fragile X syndrome.C9orf72 hypermethylation protects against repeat expansion-associated pathology in ALS/FTD.Human embryonic stem cell lines and their use in international researchClinical and molecular implications of mosaicism in FMR1 full mutations.The distribution of repressive histone modifications on silenced FMR1 alleles provides clues to the mechanism of gene silencing in fragile X syndrome.Promoter-bound trinucleotide repeat mRNA drives epigenetic silencing in fragile X syndrome.Investigating human disease using stem cell models.Epigenetic characterization of the FMR1 promoter in induced pluripotent stem cells from human fibroblasts carrying an unmethylated full mutationFMR1 epigenetic silencing commonly occurs in undifferentiated fragile X-affected embryonic stem cellsPolycomb group complexes are recruited to reactivated FMR1 alleles in Fragile X syndrome in response to FMR1 transcriptionGenome-wide analysis validates aberrant methylation in fragile X syndrome is specific to the FMR1 locus.Concise review: Fragile X proteins in stem cell maintenance and differentiationIdentification of fragile X syndrome specific molecular markers in human fibroblasts: a useful model to test the efficacy of therapeutic drugs.The FMR1 gene and fragile X-associated tremor/ataxia syndrome.
P2860
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P2860
Developmental study of fragile X syndrome using human embryonic stem cells derived from preimplantation genetically diagnosed embryos.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh
2007年學術文章
@zh-hant
name
Developmental study of fragile ...... genetically diagnosed embryos.
@en
Developmental study of fragile ...... genetically diagnosed embryos.
@nl
type
label
Developmental study of fragile ...... genetically diagnosed embryos.
@en
Developmental study of fragile ...... genetically diagnosed embryos.
@nl
prefLabel
Developmental study of fragile ...... genetically diagnosed embryos.
@en
Developmental study of fragile ...... genetically diagnosed embryos.
@nl
P2093
P1433
P1476
Developmental study of fragile ...... genetically diagnosed embryos.
@en
P2093
Achia Urbach
Dalit Ben-Yosef
Mira Malcov
Ofra Yanuka
Rachel Eiges
Tamar Schwartz
Tsvia Frumkin
Yuval Yaron
P304
P356
10.1016/J.STEM.2007.09.001
P407
P4510
P577
2007-11-01T00:00:00Z