Restoring the association of the T cell receptor with CD8 reverses anergy in human tumor-infiltrating lymphocytes.
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Turning-Off Signaling by Siglecs, Selectins, and Galectins: Chemical Inhibition of Glycan-Dependent Interactions in CancerThe Sweet Side of Immune Evasion: Role of Glycans in the Mechanisms of Cancer ProgressionThe multiple roles of the CD8 coreceptor in T cell biology: opportunities for the selective modulation of self-reactive cytotoxic T cellsA major secretory defect of tumour-infiltrating T lymphocytes due to galectin impairing LFA-1-mediated synapse completion.Early T cell signalling is reversibly altered in PD-1+ T lymphocytes infiltrating human tumorsProtein Flexibility and Conformational Entropy in Ligand Design Targeting the Carbohydrate Recognition Domain of Galectin-3The roles of Galectin-3 in autoimmunity and tumor progressionLiver is able to activate naïve CD8+ T cells with dysfunctional anti-viral activity in the murine system.WT1 peptide vaccination in combination with imatinib therapy for a patient with CML in the chronic phase.Tumor-infiltrating NY-ESO-1-specific CD8+ T cells are negatively regulated by LAG-3 and PD-1 in human ovarian cancer.Pivotal Advance: Nonfunctional lung effectors exhibit decreased calcium mobilization associated with reduced expression of ORAI1.Perspectives on Regulatory T Cell Therapies.The role of cis dimerization of signal regulatory protein alpha (SIRPalpha) in binding to CD47Islet-specific CTL cloned from a type 1 diabetes patient cause beta-cell destruction after engraftment into HLA-A2 transgenic NOD/scid/IL2RG null mice.Piecing together the family portrait of TCR-CD3 complexes.T-cell growth, cell surface organization, and the galectin-glycoprotein lattice.Interleukin-2, Interleukin-7, T cell-mediated autoimmunity, and N-glycosylation.Two opposing roles of O-glycans in tumor metastasis.Galectin-1 regulates tissue exit of specific dendritic cell populations.Galectin-3 protein regulates mobility of N-cadherin and GM1 ganglioside at cell-cell junctions of mammary carcinoma cellsGalectin-3 as a Potential Target to Prevent Cancer Metastasis.Modulation of MHC binding by lateral association of TCR and coreceptor.Immunoglobulin-like transcript receptors on human dermal CD14+ dendritic cells act as a CD8-antagonist to control cytotoxic T cell primingLack of galectin-1 or galectin-3 alters B cell deletion and anergy in an autoantibody transgene modelThe regulatory power of glycans and their binding partners in immunityImmune suppression in tumors as a surmountable obstacle to clinical efficacy of cancer vaccinesAntigen sensitivity is a major determinant of CD8+ T-cell polyfunctionality and HIV-suppressive activity.Mammalian glycosylation in immunity.Tricks with tetramers: how to get the most from multimeric peptide-MHC.Tumor immunosuppressive environment: effects on tumor-specific and nontumor antigen immune responses.Metabolism, cell surface organization, and disease.The road less traveled: regulation of leukocyte migration across vascular and lymphatic endothelium by galectins.Tumor-infiltrating lymphocytes: apparently good for melanoma patients. But why?Metabolism, LXR/LXR ligands, and tumor immune escape.Variation of tumor-infiltrating lymphocytes in human cancers: controversy on clinical significance.Nanoscale membrane organization: where biochemistry meets advanced microscopy.Evolving mechanistic insights into galectin functions.Expression of a functional CCR2 receptor enhances tumor localization and tumor eradication by retargeted human T cells expressing a mesothelin-specific chimeric antibody receptor.Vaccines for established cancer: overcoming the challenges posed by immune evasion.Strategies to reverse melanoma-induced T-cell dysfunction
P2860
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P2860
Restoring the association of the T cell receptor with CD8 reverses anergy in human tumor-infiltrating lymphocytes.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
Restoring the association of t ...... umor-infiltrating lymphocytes.
@en
type
label
Restoring the association of t ...... umor-infiltrating lymphocytes.
@en
prefLabel
Restoring the association of t ...... umor-infiltrating lymphocytes.
@en
P2093
P1433
P1476
Restoring the association of t ...... umor-infiltrating lymphocytes.
@en
P2093
Claire Hivroz
Danièle Godelaine
Didier Colau
Immanuel F Luescher
Julie Nicaise
Michel Mourad
Nathalie Demotte
Pierre J Courtoy
Pierre van der Bruggen
Thierry Boon
P304
P356
10.1016/J.IMMUNI.2008.01.011
P407
P577
2008-03-01T00:00:00Z