The non-catalytic N-terminal extension of formylglycine-generating enzyme is required for its biological activity and retention in the endoplasmic reticulum.
about
Evaluation of sulfatase-directed quinone methide traps for proteomics.Reconstitution of Formylglycine-generating Enzyme with Copper(II) for Aldehyde Tag Conversion.Rapid degradation of an active formylglycine generating enzyme variant leads to a late infantile severe form of multiple sulfatase deficiency.Formylglycine, a post-translationally generated residue with unique catalytic capabilities and biotechnology applications.Proprotein convertases process and thereby inactivate formylglycine-generating enzyme.SUMF1 mutations affecting stability and activity of formylglycine generating enzyme predict clinical outcome in multiple sulfatase deficiency.HpSumf1 is involved in the activation of sulfatases responsible for regulation of skeletogenesis during sea urchin development.Eukaryotic formylglycine-generating enzyme catalyses a monooxygenase type of reaction.
P2860
Q33899573-A32B9CC2-5EC4-4560-830D-B1D012B1087EQ35860701-3F4D60B6-22B4-4552-94FF-8F57904ACF2EQ37102138-1AD1EFD7-DD4B-4F02-8E40-E62E1921CDBBQ38290367-9AD43D26-AF3E-45A2-8A7D-4DDD75EF24E6Q39216555-7414B1B5-87C7-47DC-AB2A-5C5FBF4192FAQ42701927-553808EB-889B-480A-BDBC-BAA1AC5830B1Q43580254-4DF39419-6414-4FC3-BF33-26074902A1DEQ51007589-FEF27C22-3CA6-4415-87C5-36B23835E1A5
P2860
The non-catalytic N-terminal extension of formylglycine-generating enzyme is required for its biological activity and retention in the endoplasmic reticulum.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
The non-catalytic N-terminal e ...... in the endoplasmic reticulum.
@en
type
label
The non-catalytic N-terminal e ...... in the endoplasmic reticulum.
@en
prefLabel
The non-catalytic N-terminal e ...... in the endoplasmic reticulum.
@en
P2093
P2860
P356
P1476
The non-catalytic N-terminal e ...... in the endoplasmic reticulum.
@en
P2093
Bernhard Schmidt
Malaiyalam Mariappan
Santosh Lakshmi Gande
Thomas Dierks
P2860
P304
11556-11564
P356
10.1074/JBC.M707858200
P407
P577
2008-02-27T00:00:00Z