Transthyretin binding to A-Beta peptide--impact on A-Beta fibrillogenesis and toxicity.
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Transthyretin and the brain re-visited: is neuronal synthesis of transthyretin protective in Alzheimer's disease?Human metallothioneins 2 and 3 differentially affect amyloid-beta binding by transthyretinStructural and mutational analyses of protein-protein interactions between transthyretin and retinol-binding proteinDeletion of Irs2 reduces amyloid deposition and rescues behavioural deficits in APP transgenic miceImplications of protein structure instability: from physiological to pathological secondary structure.Transthyretin variants with improved inhibition of β-amyloid aggregation.Transthyretin protects against A-beta peptide toxicity by proteolytic cleavage of the peptide: a mechanism sensitive to the Kunitz protease inhibitor.The systemic amyloid precursor transthyretin (TTR) behaves as a neuronal stress protein regulated by HSF1 in SH-SY5Y human neuroblastoma cells and APP23 Alzheimer's disease model mice.Transthyretin-derived peptides as β-amyloid inhibitors.Association of TTR polymorphisms with hippocampal atrophy in Alzheimer disease families.Characterization of the interaction of β-amyloid with transthyretin monomers and tetramers.Stability of the transthyretin molecule as a key factor in the interaction with a-beta peptide--relevance in Alzheimer's disease.Serum and cerebrospinal fluid levels of transthyretin in Lewy body disorders with and without dementia.Ovine colostrum nanopeptide affects amyloid beta aggregation.Neuronal production of transthyretin in human and murine Alzheimer's disease: is it protective?Transthyretin Induces Insulin-like Growth Factor I Nuclear Translocation Regulating Its Levels in the HippocampusInfluence of Coding Variability in APP-Aβ Metabolism Genes in Sporadic Alzheimer's Disease.Transthyretin participates in beta-amyloid transport from the brain to the liver--involvement of the low-density lipoprotein receptor-related protein 1?Transthyretin as both a sensor and a scavenger of β-amyloid oligomersDifferential modification of Cys10 alters transthyretin's effect on beta-amyloid aggregation and toxicity.Resveratrol administration increases Transthyretin protein levels ameliorating AD features - importance of transthyretin tetrameric stability.Mechanisms of transthyretin inhibition of β-amyloid aggregation in vitro.Evolutionary changes to transthyretin: structure-function relationships.Molecular basis for certain neuroprotective effects of thyroid hormone.Metallothioneins in Prion- and Amyloid-Related Diseases.Sex Hormones Protect Against Amyloid-β Induced Oxidative Stress in the Choroid Plexus Cell Line Z310.Cross-interactions between the Alzheimer Disease Amyloid-β Peptide and Other Amyloid Proteins: A Further Aspect of the Amyloid Cascade Hypothesis.Sex Hormone Decline and Amyloid β Synthesis, Transport and Clearance in the Brain.Transthyretin and BRICHOS: The Paradox of Amyloidogenic Proteins with Anti-Amyloidogenic Activity for Aβ in the Central Nervous System.Testing the therapeutic potential of doxycycline in a Drosophila melanogaster model of Alzheimer disease.Transthyretin Suppresses Amyloid-β Secretion by Interfering with Processing of the Amyloid-β Protein PrecursorCerebrospinal Fluid Proteins as Regulators of Beta-amyloid Aggregation and Toxicity.Rare Genetic Variants of the Transthyretin Gene Are Associated with Alzheimer's Disease in Han Chinese.Progesterone enhances transthyretin expression in the rat choroid plexus in vitro and in vivo via progesterone receptor.Transthyretin stability is critical in assisting beta amyloid clearance- Relevance of transthyretin stabilization in Alzheimer's disease.The Expression of Transthyretin and Amyloid-β Protein Precursor is Altered in the Brain of Idiopathic Normal Pressure Hydrocephalus Patients.Transthyretin Mimetics as Anti-β-Amyloid Agents: A comparison of peptide and protein approaches.Measurement of Aβ1-42 in cerebrospinal fluid is influenced by matrix effects.Transthyretin in peripheral nerve regenerationAccurate, strong, and stable reporting of choroid plexus epithelial cells in transgenic mice using a human transthyretin BAC
P2860
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P2860
Transthyretin binding to A-Beta peptide--impact on A-Beta fibrillogenesis and toxicity.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
Transthyretin binding to A-Beta peptide--impact on A-Beta fibrillogenesis and toxicity.
@en
type
label
Transthyretin binding to A-Beta peptide--impact on A-Beta fibrillogenesis and toxicity.
@en
prefLabel
Transthyretin binding to A-Beta peptide--impact on A-Beta fibrillogenesis and toxicity.
@en
P2860
P50
P1433
P1476
Transthyretin binding to A-Beta peptide--impact on A-Beta fibrillogenesis and toxicity
@en
P2093
A Gonçalves
P2860
P304
P356
10.1016/J.FEBSLET.2008.02.034
P407
P577
2008-02-22T00:00:00Z