EGFR and ErbB2 are functionally coupled to CD44 and regulate shedding, internalization and motogenic effect of CD44.
about
Coclustering of ErbB1 and ErbB2 revealed by FRET-sensitized acceptor bleaching.Transforming growth factor-β1 (TGF-β1)-stimulated fibroblast to myofibroblast differentiation is mediated by hyaluronan (HA)-facilitated epidermal growth factor receptor (EGFR) and CD44 co-localization in lipid rafts.MicroRNA-7 inhibition rescues age-associated loss of epidermal growth factor receptor and hyaluronan-dependent differentiation in fibroblasts.Overexpression of CD44 accompanies acquired tamoxifen resistance in MCF7 cells and augments their sensitivity to the stromal factors, heregulin and hyaluronan.Neural stem cell niches: roles for the hyaluronan-based extracellular matrix.Binding of trastuzumab to ErbB2 is inhibited by a high pericellular density of hyaluronan.Epithelial-to-mesenchymal transition (EMT) confers primary resistance to trastuzumab (Herceptin).Intracellular domain fragment of CD44 alters CD44 function in chondrocytes.The combination of trastuzumab and pertuzumab administered at approved doses may delay development of trastuzumab resistance by additively enhancing antibody-dependent cell-mediated cytotoxicity.Shedding light on proteolytic cleavage of CD44: the responsible sheddase and functional significance of shedding.Physical biology in cancer. 3. The role of cell glycocalyx in vascular transport of circulating tumor cells.Overexpression of Specific CD44 Isoforms Is Associated with Aggressive Cell Features in Acquired Endocrine Resistance.Transportin regulates nuclear import of CD44.Conditions of tumor-associated antigens as a proper target for therapeutic antibodies against solid cancers.Hyaluronan facilitates transforming growth factor-β1-dependent proliferation via CD44 and epidermal growth factor receptor interactionMeasurements of heterotypic associations between cluster of differentiation CD74 and CD44 in human breast cancer-derived cells.Soluble CD44 concentration in the serum and peritoneal fluid samples of patients with different stages of endometriosis.
P2860
Q33954390-7F562BB4-02CA-47A6-8510-54AC06DDB001Q34339468-EBE3A9AE-9D85-489B-9812-EB8365533BB4Q34378316-3473CC48-BD14-4B57-9E87-60618DA1601BQ34435089-9A4020FB-D0D7-454B-BEFC-82871E34F2D9Q35666757-B63A94B3-ACE4-4AE4-8AF1-9482248E2835Q36285897-626727E6-4F86-48E2-9679-3E3B1B468281Q36426509-BBFE4987-02F6-4102-AF5A-D799322D0B57Q37151005-4A7B8780-BCBC-4468-BB91-2A8207DDF547Q37327307-DA6EE01C-E1CA-47C9-A8E4-28BDF844C6C3Q37381798-5E93E9E2-7C5D-4E3C-AE8C-B2E93FD10955Q37575305-69222707-8737-467C-BFC5-915D5F09E5C3Q38845190-DDB441D3-89DD-4768-841F-ADCC775B4B0CQ39675125-0A4B1919-DD7F-4364-835F-5D1F1ABD81F7Q41902817-4091D2D3-D68D-4B72-8556-4CF6B343F6D2Q42733192-555996CE-F6C4-4D67-A178-AB37263B16CBQ47138678-8C45B656-3C35-4223-945F-C53763985215Q51051978-2251ECD7-009A-4296-938E-EA2A0B9A9FBE
P2860
EGFR and ErbB2 are functionally coupled to CD44 and regulate shedding, internalization and motogenic effect of CD44.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
EGFR and ErbB2 are functionall ...... and motogenic effect of CD44.
@en
type
label
EGFR and ErbB2 are functionall ...... and motogenic effect of CD44.
@en
prefLabel
EGFR and ErbB2 are functionall ...... and motogenic effect of CD44.
@en
P2093
P50
P1433
P1476
EGFR and ErbB2 are functionall ...... n and motogenic effect of CD44
@en
P2093
Hideyuki Saya
János Szöllosi
Márk Barok
Zsuzsanna Pályi-Krekk
P304
P356
10.1016/J.CANLET.2008.01.014
P407
P577
2008-02-13T00:00:00Z