Gli2 upregulates cFlip and renders basal cell carcinoma cells resistant to death ligand-mediated apoptosis.
about
Allogeneic transplantation, Fas signaling, and dysregulation of hepcidinc-FLIP, a master anti-apoptotic regulatorHedgehog signaling pathway mediates invasion and metastasis of hepatocellular carcinoma via ERK pathway.Transcriptional suppression of mir-29b-1/mir-29a promoter by c-Myc, hedgehog, and NF-kappaB.Stem cell pathways contribute to clinical chemoresistance in ovarian cancerBasal cell carcinoma: from the molecular understanding of the pathogenesis to targeted therapy of progressive disease.Basal cell carcinomas: attack of the hedgehog.The Hedgehog signalling pathway regulates autophagy.Expression of glioma-associated oncogene 2 (Gli 2) is correlated with poor prognosis in patients with hepatocellular carcinoma undergoing hepatectomyhnRNPK inhibits GSK3β Ser9 phosphorylation, thereby stabilizing c-FLIP and contributes to TRAIL resistance in H1299 lung adenocarcinoma cells.Transgenic overexpression of Sox17 promotes oligodendrocyte development and attenuates demyelination.Significance of the hedgehog pathway-associated proteins Gli-1 and Gli-2 and the epithelial-mesenchymal transition-associated proteins Twist and E-cadherin in hepatocellular carcinoma.Mechanisms of Hedgehog signalling in cancer.Wnt and SHH in prostate cancer: trouble mongers occupy the TRAIL towards apoptosis.FLIP: molecular switch between apoptosis and necroptosis.Hedgehog signalling pathway: carcinogenesis and targeted therapyExpression of microphthalmia-associated transcription factor (MITF), which is critical for melanoma progression, is inhibited by both transcription factor GLI2 and transforming growth factor-β.GLI2-dependent c-MYC upregulation mediates resistance of pancreatic cancer cells to the BET bromodomain inhibitor JQ1.GLI2 induces genomic instability in human keratinocytes by inhibiting apoptosisThe oncogenic GLI transcription factors facilitate keratinocyte survival and transformation upon exposure to genotoxic agents.MEK1-RSK2 contributes to Hedgehog signaling by stabilizing GLI2 transcription factor and inhibiting ubiquitination.Hedgehog signaling pathway as a potential target in the treatment of advanced gastric cancer.shRNA-mediated silencing of Gli2 gene inhibits proliferation and sensitizes human hepatocellular carcinoma cells towards TRAIL-induced apoptosis.GLI3-dependent repression of DR4 mediates hedgehog antagonism of TRAIL-induced apoptosisGLI2 inhibition abrogates human leukemia stem cell dormancy.Increased cFLIP expression in thymic epithelial tumors blocks autophagy via NF-κB signalling.RKIP reduction enhances radioresistance by activating the Shh signaling pathway in non-small-cell lung cancer.
P2860
Q28386081-58BF6BEF-B240-4FF8-BB88-5D6754CF1841Q28391119-B29D742B-5214-42BA-BFD0-67911F7327D9Q33567426-ED3A19AB-9AEC-47A7-B67E-F0BC49BCA5A9Q34070947-A3372352-A83C-4CB7-9045-D3017A4D952AQ34092005-F6970453-F8DB-4359-B999-051D4440EF19Q34495423-D05D498A-837B-4544-9FE2-01629BED7805Q35687900-33D4C975-FA9B-4750-B49C-90555943DF22Q36445596-6F3B2E03-59DB-424C-BD67-2893C43200BFQ36591698-19726F87-0D1A-479C-9DDF-10870D6CADD5Q36681641-411FC4DA-D331-4A11-8362-AAFF8278938CQ37041616-446AC4A8-BF1A-4A1B-9E29-1BAAE6A54804Q37204746-3A2B7EFB-E912-4FE5-B33E-485B409FC39CQ37923514-439F4166-5D80-4C22-81E0-1D32B7C6C484Q37942610-EE5F6323-8575-441D-9464-04CF0DEB3D83Q38102627-FA9462CB-45C4-46FB-ACD5-69E7335CEA06Q38253645-698B11A1-40D2-4652-A1E0-FA2A3797E5E9Q38326193-ABDAE733-2824-49C4-8B50-FCCD4A085820Q38895410-9B2B1E62-886C-43CB-9D13-D9326086E97FQ39028802-C6640956-D1E1-4A0D-A680-D3695899AAF1Q39136441-0EF75931-08F6-432A-8375-ED2EACB7A48DQ39233200-2D70613A-B162-4102-BF61-72F6ECB267FDQ39377902-01FEB9CA-0546-4537-B020-E3B494559FDAQ39520220-E27D1B14-02B7-4DDD-9AE1-5E464A3B77CFQ39690748-A193C9EE-CB89-49F9-BA65-80C96A6CD632Q40079691-1CB8DAC9-70C5-4B7A-B9C0-6E8A3490CA9DQ45491251-DDB4E800-CE9E-4153-A601-641366898DAFQ47097935-9634C77B-BEF4-4E95-BCC1-BCF2161CBF3F
P2860
Gli2 upregulates cFlip and renders basal cell carcinoma cells resistant to death ligand-mediated apoptosis.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Gli2 upregulates cFlip and ren ...... ath ligand-mediated apoptosis.
@en
type
label
Gli2 upregulates cFlip and ren ...... ath ligand-mediated apoptosis.
@en
prefLabel
Gli2 upregulates cFlip and ren ...... ath ligand-mediated apoptosis.
@en
P2093
P2860
P356
P1433
P1476
Gli2 upregulates cFlip and ren ...... ath ligand-mediated apoptosis.
@en
P2093
P2860
P2888
P304
P356
10.1038/ONC.2008.5
P407
P577
2008-02-11T00:00:00Z
P5875
P6179
1039349628