Statin synergizes with LPS to induce IL-1beta release by THP-1 cells through activation of caspase-1.
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Weekly oral alendronate in mevalonate kinase deficiencyMevalonate kinase deficiency: current perspectivesIs immunity a mechanism contributing to statin-induced diabetes?Mevalonate Pathway Blockade, Mitochondrial Dysfunction and Autophagy: A Possible LinkHyper-IgD syndrome/mevalonate kinase deficiency: what is new?Bacillus anthracis capsule activates caspase-1 and induces interleukin-1beta release from differentiated THP-1 and human monocyte-derived dendritic cells.3-Hydroxyl-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor (statin)-induced 28-kDa interleukin-1β interferes with mature IL-1β signalingThe inhibition of mevalonate pathway induces upregulation of NALP3 expression: new insight in the pathogenesis of mevalonate kinase deficiency.Monogenic autoinflammatory diseases: new insights into clinical aspects and pathogenesis.Statins and pulmonary fibrosis: the potential role of NLRP3 inflammasome activation.11-Month-Old Infant With Periodic Fevers, Recurrent Liver Dysfunction, and Perforin Gene Polymorphism.Bisphosphonate Induces Osteonecrosis of the Jaw in Diabetic Mice via NLRP3/Caspase-1-Dependent IL-1β Mechanism.Defects in mitochondrial clearance predispose human monocytes to interleukin-1β hypersecretion.Regulation of dolichol-linked glycosylation.Mevalonate kinase deficiency and neuroinflammation: balance between apoptosis and pyroptosis.Mevalonate kinase deficiency in two sisters with therapeutic response to anakinra: case report and review of the literature.Treatment of hyperimmunoglobulinemia D syndrome with biologics in children: review of the literature and Finnish experience.Targeting Inflammation Through a Physical Active Lifestyle and Pharmaceuticals for the Treatment of Type 2 Diabetes.Unprenylated RhoA contributes to IL-1β hypersecretion in mevalonate kinase deficiency model through stimulation of Rac1 activity.Block of the mevalonate pathway triggers oxidative and inflammatory molecular mechanisms modulated by exogenous isoprenoid compounds.Lovastatin dose-dependently potentiates the pro-inflammatory activity of lipopolysaccharide both in vitro and in vivo.Atorvastatin promotes the expansion of myeloid-derived suppressor cells and attenuates murine colitis.Posttranslational Modification as a Critical Determinant of Cytoplasmic Innate Immune Recognition.Defect in mevalonate pathway induces pyroptosis in Raw 264.7 murine monocytes.The farnesyltransferase inhibitors tipifarnib and lonafarnib inhibit cytokines secretion in a cellular model of mevalonate kinase deficiency.TLR2/TLR4-dependent exaggerated cytokine production in hyperimmunoglobulinaemia D and periodic fever syndrome.Mevalonate kinase deficiency leads to decreased prenylation of Rab GTPases.A case of hyperimmunoglobulinemia d syndrome successfully treated with canakinumab.Roles of the Mevalonate Pathway and Cholesterol Trafficking in Pulmonary Host Defense.Reduced serpinB9-mediated caspase-1 inhibition can contribute to autoinflammatory disease.Mouse model of mevalonate kinase deficiency: comparison of cytokine and chemokine profile with that of human patients.Anti-inflammatory and cytoprotective effects of a squalene synthase inhibitor, TAK-475 active metabolite-I, in immune cells simulating mevalonate kinase deficiency (MKD)-like condition.Statin effects on regulatory and proinflammatory factors in chronic idiopathic urticaria.
P2860
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P2860
Statin synergizes with LPS to induce IL-1beta release by THP-1 cells through activation of caspase-1.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Statin synergizes with LPS to ...... rough activation of caspase-1.
@en
type
label
Statin synergizes with LPS to ...... rough activation of caspase-1.
@en
prefLabel
Statin synergizes with LPS to ...... rough activation of caspase-1.
@en
P2093
P1433
P1476
Statin synergizes with LPS to ...... rough activation of caspase-1.
@en
P2093
Ger T Rijkers
Hans R Waterham
Ingrid Schellens
Joost Frenkel
Loes M Kuijk
Paul J Coffer
Saskia H Mandey
P304
P356
10.1016/J.MOLIMM.2007.12.008
P577
2008-02-01T00:00:00Z