Constitutive activation of S6 kinase by deletion of amino-terminal autoinhibitory and rapamycin sensitivity domains.
about
Elucidating TOR signaling and rapamycin action: lessons from Saccharomyces cerevisiae.Inhibition of the Ca2+/calmodulin-dependent protein kinase I cascade by cAMP-dependent protein kinaseModulation of the mammalian target of rapamycin pathway by diacylglycerol kinase-produced phosphatidic acidDifferential activation of p70 and p85 S6 kinase isoforms during cardiac hypertrophy in the adult mammal.Divergent Anabolic Signalling responses of Murine Soleus and Tibialis Anterior Muscles to Chronic 2G Hypergravity.Multiple pathways control protein kinase C phosphorylation.The target of rapamycin (TOR) proteinsA role of the kinase mTOR in cellular transformation induced by the oncoproteins P3k and Akt.Serum-stimulated, rapamycin-sensitive phosphorylation sites in the eukaryotic translation initiation factor 4GI.Cyclin-dependent Kinase 5 (Cdk5)-dependent Phosphorylation of p70 Ribosomal S6 Kinase 1 (S6K) Is Required for Dendritic Spine Morphogenesis.Alteration of Akt activity increases chemotherapeutic drug and hormonal resistance in breast cancer yet confers an achilles heel by sensitization to targeted therapy.Contributions of the Raf/MEK/ERK, PI3K/PTEN/Akt/mTOR and Jak/STAT pathways to leukemia.Proteolytic cleavage of p70 ribosomal S6 kinase by caspase-3 during DNA damage-induced apoptosis.The principal rapamycin-sensitive p70(s6k) phosphorylation sites, T-229 and T-389, are differentially regulated by rapamycin-insensitive kinase kinases.Targeting the RAF/MEK/ERK, PI3K/AKT and p53 pathways in hematopoietic drug resistance.Role of the phosphatidylinositol 3-kinase/Akt and mTOR/P70S6-kinase pathways in the proliferation and apoptosis in multiple myeloma.A new role for the p85-phosphatidylinositol 3-kinase regulatory subunit linking FRAP to p70 S6 kinase activation.Farnesyltransferase inhibitor induces rapid growth arrest and blocks p70s6k activation by multiple stimuli.Osmotic stress inhibits p70/85 S6 kinase through activation of a protein phosphatase.Phosphorylation sites in the autoinhibitory domain participate in p70(s6k) activation loop phosphorylation.Indinavir impairs protein synthesis and phosphorylations of MAPKs in mouse C2C12 myocytes.Protein kinase D activation by deletion of its cysteine-rich motifs.Rapamycin inhibition of baculovirus recombinant (BVr) ribosomal protein S6 kinase (S6K1) is mediated by an event other than phosphorylationRegulation of mTOR and S6K1 activation by the nPKC isoforms, PKCepsilon and PKCdelta, in adult cardiac muscle cells.Green tea polyphenol stimulates a Ras, MEKK1, MEK3, and p38 cascade to increase activator protein 1 factor-dependent involucrin gene expression in normal human keratinocytes.
P2860
Q24537557-58031347-5D57-4306-9AA3-F3500847F80CQ28140472-52080FE9-E352-444D-9676-11F5ACD951DCQ28301067-D90D8E6E-143B-453E-954B-E8E63CFEEC79Q32023669-E4D02470-7B59-48BF-922A-9BD036EE6653Q33799390-72CC299A-713B-4AA4-93E0-86E7742B2FEAQ33838086-2BD01D5E-2360-4E3F-BC44-71EA1ABAFCFAQ34287448-54788094-7707-4756-93EB-CB3A64D01ED4Q34585873-F4A2C2BF-C439-4674-B5B0-FF98A693A1E9Q34662460-24A68316-D9D3-4F94-ACC4-53999D5AF091Q35860823-05A36AAD-2DD5-46BB-A9D7-A6E0317CDFEBQ36973814-59E0B6B8-1A74-42EE-9E4D-BA37469614ABQ37109227-8BEC71E4-CB3D-4D2A-A65D-1744CF27D267Q39887685-3C8C7862-28A2-4042-92CA-03F940429715Q40020238-14DE7FB6-01D5-44D4-A007-E291415EC2F7Q40154931-0215F98D-6507-446A-A492-2F7F9656DE75Q40702649-F58A6C12-7305-4B0A-8E6D-B123BA611A56Q40771721-CE1408C3-5CC4-4B4D-B49F-F24B32DE7A9BQ40831741-19C1DB8E-3433-4103-A058-E92BD9963394Q40934280-C05C8987-D11F-4CDD-9F13-2A36C20C3771Q41034632-4668DD9D-EF23-476D-90C7-78DD1608AA01Q42464012-9122E3D5-BAA3-40BC-804C-B7C1A765BF33Q42475083-4260E461-BB45-4A02-8F9D-CFAA5FB294D6Q42569903-420F6C41-652F-4FBE-93EB-57BCFCA86930Q42913658-4E60E0C9-7C2D-48AA-99FD-69F9D20D1656Q43792260-24938FC5-97BF-470E-A269-5A1018951A7D
P2860
Constitutive activation of S6 kinase by deletion of amino-terminal autoinhibitory and rapamycin sensitivity domains.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
Constitutive activation of S6 ...... rapamycin sensitivity domains.
@en
type
label
Constitutive activation of S6 ...... rapamycin sensitivity domains.
@en
prefLabel
Constitutive activation of S6 ...... rapamycin sensitivity domains.
@en
P2860
P356
P1476
Constitutive activation of S6 ...... rapamycin sensitivity domains.
@en
P2093
Mahalingam M
Templeton DJ
P2860
P304
P356
10.1128/MCB.16.1.405
P407
P577
1996-01-01T00:00:00Z